MOQUIZONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H21N3O3
Molecular Weight	351.399
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O=C(CN1CCOCC1)N2CN(C(=O)C3=C2C=CC=C3)C4=CC=CC=C4

InChI

InChIKey=VCRQLDNIOXNDMT-UHFFFAOYSA-N

InChI=1S/C20H21N3O3/c24-19(14-21-10-12-26-13-11-21)23-15-22(16-6-2-1-3-7-16)20(25)17-8-4-5-9-18(17)23/h1-9H,10-15H2

HIDE SMILES / InChI

Molecular Formula	C20H21N3O3
Molecular Weight	351.399
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4679063 | https://www.ncbi.nlm.nih.gov/pubmed/5422206 | https://www.ncbi.nlm.nih.gov/pubmed/5536425 | https://pubs.acs.org/doi/abs/10.1021/jm00312a007

Moquizone is quinazolinone derivative with choleretic and antifibrillatory activity. Oral toxic doses of Moquizone exerted depressant effects, whereas parenteral toxic doses exerted stimulant effects on the central nervous system.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
bile acid metabolic process 2 Target ID: GO:0008206 Sources: http://www.drugfuture.com/chemdata/moquizone.html\|https://www.ncbi.nlm.nih.gov/pubmed/4679063	Modulator 846

PubMed

Title	Date	PubMed
Pharmacology of moquizone, a new choleretic drug.	1972-11	4679063

Patents

Sample Use Guides

In Vivo Use Guide

Mice LD50: 560mg/kg

Route of Administration: Intraperitoneal

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:29:39 GMT 2025` Edited by `admin` on `Mon Mar 31 18:29:39 GMT 2025`
Record UNII	EG12MD1RMA
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MOQUIZONE

Official Name

English

MOQUIZONE [MI]

Preferred Name

English

2,3-DIHYDRO-1-(MORPHOLINOACETYL)-3-PHENYL-4(1H)-QUINAZOLINONE

Systematic Name

English

moquizone [INN]

Common Name

English

Moquizone [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66913