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Details

Stereochemistry ACHIRAL
Molecular Formula C20H21N3O3
Molecular Weight 351.399
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MOQUIZONE

SMILES

O=C(CN1CCOCC1)N2CN(C(=O)C3=CC=CC=C23)C4=CC=CC=C4

InChI

InChIKey=VCRQLDNIOXNDMT-UHFFFAOYSA-N
InChI=1S/C20H21N3O3/c24-19(14-21-10-12-26-13-11-21)23-15-22(16-6-2-1-3-7-16)20(25)17-8-4-5-9-18(17)23/h1-9H,10-15H2

HIDE SMILES / InChI

Molecular Formula C20H21N3O3
Molecular Weight 351.399
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Moquizone is quinazolinone derivative with choleretic and antifibrillatory activity. Oral toxic doses of Moquizone exerted depressant effects, whereas parenteral toxic doses exerted stimulant effects on the central nervous system.

Originator

Sources: ZA 6803948; "Quinazolines" Bonola, Giuseppe; Setnikar, Ivo; Da Re, Paolo

Approval Year

Targets
PubMed

PubMed

TitleDatePubMed
Patents

Patents

Sample Use Guides

Mice LD50: 560mg/kg
Route of Administration: Intraperitoneal
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:30:05 GMT 2023
Edited
by admin
on Fri Dec 15 16:30:05 GMT 2023
Record UNII
EG12MD1RMA
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MOQUIZONE
INN   MI   WHO-DD  
INN  
Official Name English
2,3-DIHYDRO-1-(MORPHOLINOACETYL)-3-PHENYL-4(1H)-QUINAZOLINONE
Systematic Name English
moquizone [INN]
Common Name English
MOQUIZONE [MI]
Common Name English
Moquizone [WHO-DD]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C66913
Created by admin on Fri Dec 15 16:30:05 GMT 2023 , Edited by admin on Fri Dec 15 16:30:05 GMT 2023
Code System Code Type Description
ChEMBL
CHEMBL2105182
Created by admin on Fri Dec 15 16:30:05 GMT 2023 , Edited by admin on Fri Dec 15 16:30:05 GMT 2023
PRIMARY
MESH
C002376
Created by admin on Fri Dec 15 16:30:05 GMT 2023 , Edited by admin on Fri Dec 15 16:30:05 GMT 2023
PRIMARY
DRUG CENTRAL
3785
Created by admin on Fri Dec 15 16:30:05 GMT 2023 , Edited by admin on Fri Dec 15 16:30:05 GMT 2023
PRIMARY
PUBCHEM
63216
Created by admin on Fri Dec 15 16:30:05 GMT 2023 , Edited by admin on Fri Dec 15 16:30:05 GMT 2023
PRIMARY
ECHA (EC/EINECS)
243-021-2
Created by admin on Fri Dec 15 16:30:05 GMT 2023 , Edited by admin on Fri Dec 15 16:30:05 GMT 2023
PRIMARY
SMS_ID
100000080366
Created by admin on Fri Dec 15 16:30:05 GMT 2023 , Edited by admin on Fri Dec 15 16:30:05 GMT 2023
PRIMARY
CAS
19395-58-5
Created by admin on Fri Dec 15 16:30:05 GMT 2023 , Edited by admin on Fri Dec 15 16:30:05 GMT 2023
PRIMARY
NCI_THESAURUS
C66192
Created by admin on Fri Dec 15 16:30:05 GMT 2023 , Edited by admin on Fri Dec 15 16:30:05 GMT 2023
PRIMARY
EVMPD
SUB09061MIG
Created by admin on Fri Dec 15 16:30:05 GMT 2023 , Edited by admin on Fri Dec 15 16:30:05 GMT 2023
PRIMARY
EPA CompTox
DTXSID60173007
Created by admin on Fri Dec 15 16:30:05 GMT 2023 , Edited by admin on Fri Dec 15 16:30:05 GMT 2023
PRIMARY
MERCK INDEX
m354
Created by admin on Fri Dec 15 16:30:05 GMT 2023 , Edited by admin on Fri Dec 15 16:30:05 GMT 2023
PRIMARY Merck Index
INN
2589
Created by admin on Fri Dec 15 16:30:05 GMT 2023 , Edited by admin on Fri Dec 15 16:30:05 GMT 2023
PRIMARY
FDA UNII
EG12MD1RMA
Created by admin on Fri Dec 15 16:30:05 GMT 2023 , Edited by admin on Fri Dec 15 16:30:05 GMT 2023
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
Related Record Type Details
ACTIVE MOIETY