MOQUIZONE HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H21N3O3.ClH
Molecular Weight	387.86
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.O=C(CN1CCOCC1)N2CN(C(=O)C3=C2C=CC=C3)C4=CC=CC=C4

InChI

InChIKey=NUQJOBPPCCFWJG-UHFFFAOYSA-N

InChI=1S/C20H21N3O3.ClH/c24-19(14-21-10-12-26-13-11-21)23-15-22(16-6-2-1-3-7-16)20(25)17-8-4-5-9-18(17)23;/h1-9H,10-15H2;1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C20H21N3O3
Molecular Weight	351.399
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4679063 | https://www.ncbi.nlm.nih.gov/pubmed/5422206 | https://www.ncbi.nlm.nih.gov/pubmed/5536425 | https://pubs.acs.org/doi/abs/10.1021/jm00312a007

Moquizone is quinazolinone derivative with choleretic and antifibrillatory activity. Oral toxic doses of Moquizone exerted depressant effects, whereas parenteral toxic doses exerted stimulant effects on the central nervous system.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
bile acid metabolic process 2 Target ID: GO:0008206 Sources: http://www.drugfuture.com/chemdata/moquizone.html\|https://www.ncbi.nlm.nih.gov/pubmed/4679063	Modulator 846

PubMed

Title	Date	PubMed
Pharmacology of moquizone, a new choleretic drug.	1972-11	4679063

Patents

Sample Use Guides

In Vivo Use Guide

Mice LD50: 560mg/kg

Route of Administration: Intraperitoneal

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:49:28 GMT 2025` Edited by `admin` on `Mon Mar 31 18:49:28 GMT 2025`
Record UNII	51I2PZ39ND
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-291563

Preferred Name

English

MOQUIZONE HYDROCHLORIDE

Common Name

English

1-MORPHOLINO-ACETYL-3-PHENYL-2,3-DIHYDRO-4(1H)-QUINAZOLINONE HYDROCHLORIDE

Common Name

English

MOQUIZONE HYDROCHLORIDE [MI]

Common Name

English

Moquizone hydrochloride [WHO-DD]

Common Name

English

Code System Code Type Description

PUBCHEM

63401