Details
| Stereochemistry | UNKNOWN |
| Molecular Formula | C18H31N3O3 |
| Molecular Weight | 337.457 |
| Optical Activity | ( + ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)NCC(O)COC1=CC=C(CCNC(=O)NC(C)C)C=C1
InChI
InChIKey=PKWZWSXSCKVUJB-UHFFFAOYSA-N
InChI=1S/C18H31N3O3/c1-13(2)20-11-16(22)12-24-17-7-5-15(6-8-17)9-10-19-18(23)21-14(3)4/h5-8,13-14,16,20,22H,9-12H2,1-4H3,(H2,19,21,23)
| Molecular Formula | C18H31N3O3 |
| Molecular Weight | 337.457 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Originator
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Evidence for an interaction between the beta-blocker pafenolol and bile salts in the intestinal lumen of the rat leading to dose-dependent oral absorption and double peaks in the plasma concentration-time profile. | 1993-06 |
|
| Dose-dependent intestinal absorption and significant intestinal excretion (exsorption) of the beta-blocker pafenolol in the rat. | 1993-05 |
|
| Pafenolol in hypertension: a double-blind randomized trial of a new beta 1-selective adrenoceptor blocker. | 1986-01-01 |
|
| Pafenolol, a highly selective beta 1-adrenoceptor-antagonist, in asthmatic patients: interaction with terbutaline. | 1983-01 |
Patents
Sample Use Guides
Intravenous pafenolol (5 mg and 7.5 mg), metoprolol (15 mg), and saline were given double-blind at random and thereafter four increasing doses of terbutaline were given intravenously to seven asthmatic patients with reproducible reversibility of airways obstruction.
Route of Administration:
Intravenous
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 23:10:50 GMT 2025
by
admin
on
Mon Mar 31 23:10:50 GMT 2025
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| Record UNII |
E6X8CBK4RR
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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Common Name | English | ||
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Common Name | English |
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E6X8CBK4RR
Created by
admin on Mon Mar 31 23:10:50 GMT 2025 , Edited by admin on Mon Mar 31 23:10:50 GMT 2025
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178968-79-1
Created by
admin on Mon Mar 31 23:10:50 GMT 2025 , Edited by admin on Mon Mar 31 23:10:50 GMT 2025
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ENANTIOMER -> ENANTIOMER |
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RACEMATE -> ENANTIOMER |
