MIPASETAMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 07:24:10 GMT 2025` Edited by `admin` on `Wed Apr 02 07:24:10 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	DCI3L5GHC9
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

mipasetamab [INN]

Preferred Name

English

MIPASETAMAB

Official Name

English

IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS AXL (AXL RECEPTOR TYROSINE KINASE, TYROSINE-PROTEIN KINASE RECEPTOR UFO)), HUMANIZED MONOCLONAL ANTIBODY (MIPASETAMAB)

Common Name

English

1H12-HAKB

Code

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN RECEPTOR TYROSINE KINASE AXL) (HUMAN-MUS MUSCULUS MONOCLONAL 1H12 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL 1H12 .KAPPA.-CHAIN, DIMER, 302,302'-BIS(N-(O-2-(ACETYLAMINO)-6-AZIDO-2,6-DIDEOXY-.BETA.-D-GALAC

Common Name

English

IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS TYROSINE-PROTEIN KINASE RECEPTOR UFO (AXL ONCOGENE; EC=2.7.10.1)); HUMANIZED MONOCLONAL ANTIBODY; .GAMMA.1 HEAVY CHAIN HUMANIZED (1-451) (VH HUMANIZED (HOMO SAPIENS IGHV3-30*03 (93%)-(IGHD)-IGHJ4*01 (92%)) (8.8

Common Name

English

MIPASETAMAB [USAN]

Common Name

English

1H12-GALNACN3

Code

English

Code System Code Type Description

INN

11483

Created by admin on Wed Apr 02 07:24:10 GMT 2025 , Edited by admin on Wed Apr 02 07:24:10 GMT 2025

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FDA UNII

DCI3L5GHC9

Created by admin on Wed Apr 02 07:24:10 GMT 2025 , Edited by admin on Wed Apr 02 07:24:10 GMT 2025

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CAS

2361055-48-1

Created by admin on Wed Apr 02 07:24:10 GMT 2025 , Edited by admin on Wed Apr 02 07:24:10 GMT 2025

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USAN

JK-249

Created by admin on Wed Apr 02 07:24:10 GMT 2025 , Edited by admin on Wed Apr 02 07:24:10 GMT 2025

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SMS_ID

300000032572

Created by admin on Wed Apr 02 07:24:10 GMT 2025 , Edited by admin on Wed Apr 02 07:24:10 GMT 2025

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NCI_THESAURUS

C175822

Created by admin on Wed Apr 02 07:24:10 GMT 2025 , Edited by admin on Wed Apr 02 07:24:10 GMT 2025

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From	To
2_225	4_215
1_225	3_215
1_22	1_96
2_22	2_96
1_149	1_205
2_149	2_205
1_231	2_231
1_234	2_234
1_266	1_326
2_266	2_326
1_372	1_430
2_372	2_430
3_23	3_89
4_23	4_89
3_135	3_195
4_135	4_195

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_302
N	2_302

Related Record Type Details


					71KV7F609O

MIPASETAMAB UZOPTIRINE

CONJUGATE -> PARENT

Amount:

Related Record Type Details


					71KV7F609O

MIPASETAMAB UZOPTIRINE

ACTIVE MOIETY

Comments:

Immunomodulator, antineoplastic

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS			PIDOLIC ACID	SZB83O1W42
AMINO_ACID_SUBSTITUTION	[1_302] [2_302]	SITE_SPECIFIC		Amount:	UNSPECIFIED SUBSTANCE	eed341e7 (not in database)
AMINO_ACID_SUBSTITUTION	[1_302]	SITE_SPECIFIC		Amount:	UNSPECIFIED SUBSTANCE	d2a1f71b (not in database)

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL