FELIPYRINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C15H20N2O
Molecular Weight	244.3321
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FELIPYRINE

Structure Search

SMILES

O=C1C(CCN1C2=CC=CC=C2)N3CCCCC3

InChI

InChIKey=TYGVJQQISVEFSH-UHFFFAOYSA-N

InChI=1S/C15H20N2O/c18-15-14(16-10-5-2-6-11-16)9-12-17(15)13-7-3-1-4-8-13/h1,3-4,7-8,14H,2,5-6,9-12H2

HIDE SMILES / InChI

Molecular Formula	C15H20N2O
Molecular Weight	244.3321
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://link.springer.com/book/10.1007/978-1-4757-2085-3 | https://www.ncbi.nlm.nih.gov/pubmed/5960895

Felipyrine is a 1-aryl-2-pyrrolidinone derivative exerting anti-inflammatory activity.

Originator

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
inflammatory response to antigenic stimulus 2 Target ID: GO:0002437 Sources: https://www.ncbi.nlm.nih.gov/pubmed/5960895	Inhibitor 8297

PubMed

PubMed

Title	Date	PubMed
Synthesis and antiinflammatory activity of a series 1-aryl-2-pyrrolidinone derivatives.	1966 May	5960895

Patents

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:31:45 UTC 2023` Edited by `admin` on `Fri Dec 15 16:31:45 UTC 2023`
Record UNII	D9FU86687U
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FELIPYRINE

Official Name

English

2-PYRROLIDINONE, 1-PHENYL-3-(1-PIPERIDINYL)-

Systematic Name

English

felipyrine [INN]

Common Name

English

PYPEPYRONE

Common Name

English

2-PYRROLIDINONE, 1-PHENYL-3-PIPERIDINO-

Common Name

English

1-PHENYL-3-PIPERIDINO-2-PYRROLIDINONE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C257

Created by admin on Fri Dec 15 16:31:45 UTC 2023 , Edited by admin on Fri Dec 15 16:31:45 UTC 2023

Code System Code Type Description

SMS_ID

100000081257

Created by admin on Fri Dec 15 16:31:45 UTC 2023 , Edited by admin on Fri Dec 15 16:31:45 UTC 2023

PRIMARY

EVMPD

SUB07528MIG

Created by admin on Fri Dec 15 16:31:45 UTC 2023 , Edited by admin on Fri Dec 15 16:31:45 UTC 2023

PRIMARY

INN

1955

Created by admin on Fri Dec 15 16:31:45 UTC 2023 , Edited by admin on Fri Dec 15 16:31:45 UTC 2023

PRIMARY

PUBCHEM

71108

Created by admin on Fri Dec 15 16:31:45 UTC 2023 , Edited by admin on Fri Dec 15 16:31:45 UTC 2023

PRIMARY

ChEMBL

CHEMBL2105856

Created by admin on Fri Dec 15 16:31:45 UTC 2023 , Edited by admin on Fri Dec 15 16:31:45 UTC 2023

PRIMARY

EPA CompTox

DTXSID80862805

Created by admin on Fri Dec 15 16:31:45 UTC 2023 , Edited by admin on Fri Dec 15 16:31:45 UTC 2023

PRIMARY

FDA UNII

D9FU86687U

Created by admin on Fri Dec 15 16:31:45 UTC 2023 , Edited by admin on Fri Dec 15 16:31:45 UTC 2023

PRIMARY

CAS

1980-49-0

Created by admin on Fri Dec 15 16:31:45 UTC 2023 , Edited by admin on Fri Dec 15 16:31:45 UTC 2023

PRIMARY

NCI_THESAURUS

C65632

Created by admin on Fri Dec 15 16:31:45 UTC 2023 , Edited by admin on Fri Dec 15 16:31:45 UTC 2023

PRIMARY

Related Record Type Details


					2PM7Q4JDT3

FELIPYRINE, (R)-

ENANTIOMER -> RACEMATE


					35F834RZUM

FELIPYRINE, (S)-

ENANTIOMER -> RACEMATE

Related Record Type Details


					D9FU86687U

ACTIVE MOIETY