LOFEMIZOLE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H9ClN2
Molecular Weight	192.645
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=C(N=CN1)C2=CC=C(Cl)C=C2

InChI

InChIKey=MBKWNJVQSFBLQI-UHFFFAOYSA-N

InChI=1S/C10H9ClN2/c1-7-10(13-6-12-7)8-2-4-9(11)5-3-8/h2-6H,1H3,(H,12,13)

HIDE SMILES / InChI

Molecular Formula	C10H9ClN2
Molecular Weight	192.645
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6501522 | https://www.google.com/patents/US20010023254

Lofemizole is a non-steroidal anti-inflammatory drug. Lofemizole has proved to possess an interesting antiphlogistic activity in both animals and humans, associated with a favorable gastric and systemic tolerability.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Inflammation 105 Sources: https://www.ncbi.nlm.nih.gov/pubmed/6501522 https://www.google.com/patents/US20010023254	Primary		Not Provided 511	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
Gas--liquid chromatographic evaluation of lofemizole in biological samples for pharmacokinetic investigations. Comparison of two analytical methods.	1984-09-14	6501522

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:23:07 GMT 2025` Edited by `admin` on `Mon Mar 31 18:23:07 GMT 2025`
Record UNII	D8G23FPC3P
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

4-(P-CHLOROPHENYL)-5-METHYLIMIDAZOLE

Preferred Name

English

LOFEMIZOLE

Official Name

English

lofemizole [INN]

Common Name

English

1H-IMIDAZOLE, 4-(4-CHLOROPHENYL)-5-METHYL-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C257