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Details

Stereochemistry ACHIRAL
Molecular Formula C10H9ClN2
Molecular Weight 192.645
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LOFEMIZOLE

SMILES

CC1=C(N=CN1)C2=CC=C(Cl)C=C2

InChI

InChIKey=MBKWNJVQSFBLQI-UHFFFAOYSA-N
InChI=1S/C10H9ClN2/c1-7-10(13-6-12-7)8-2-4-9(11)5-3-8/h2-6H,1H3,(H,12,13)

HIDE SMILES / InChI
Molecular Formula C10H9ClN2
Molecular Weight 192.645
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Lofemizole is a non-steroidal anti-inflammatory drug. Lofemizole has proved to possess an interesting antiphlogistic activity in both animals and humans, associated with a favorable gastric and systemic tolerability.

Approval Year

Unknown
149,124

Conditions

ConditionModalityTargetsHighest PhaseProduct
Inflammation
105
 Primary
Not Provided
511
Unknown

PubMed

Patents

EP1992355A1
4
US20010023254
3
US8343529
2
US9771337
2

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
D8G23FPC3P
Record Status Validated (UNII)
Record Version
NIH
NCATS
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