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Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Wed Apr 02 21:08:04 GMT 2025
Edited
by admin
on Wed Apr 02 21:08:04 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
D859Q6K2XE
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
H-gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV1-2*06 (88.8%) -(IGHD) -IGHJ6*01 (90.9%) T123>L (114), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120, CH3 E12, M14, G1v14 CH2 A1.3, A1.2 (CH1 R120
Preferred Name English
Recibokibart
INN  
Official Name English
Immunoglobulin G1 [236-alanine,237-alanine,de-C-terminal-lysine], anti-(human interleukin 36 receptor) (human-Mus musculus monoclonal HB0034 ?1-chain), disulfide with human-Mus musculus monoclonal HB0034 ?-chain, dimer
Common Name English
immunoglobulin G1-kappa, anti-[Homo sapiens IL1RL2 (interleukin 1 receptor like 2, IL1 receptor-related protein 2, IL1Rrp2, IL1RRP2, IL-36 receptor, IL-36R)], humanized monoclonal antibody
Common Name English
recibokibart [INN]
Common Name English
Code System Code Type Description
INN
13255
Created by admin on Wed Apr 02 21:08:04 GMT 2025 , Edited by admin on Wed Apr 02 21:08:04 GMT 2025
PRIMARY
SMS_ID
300000056827
Created by admin on Wed Apr 02 21:08:04 GMT 2025 , Edited by admin on Wed Apr 02 21:08:04 GMT 2025
PRIMARY
NCI_THESAURUS
C211763
Created by admin on Wed Apr 02 21:08:04 GMT 2025 , Edited by admin on Wed Apr 02 21:08:04 GMT 2025
PRIMARY
FDA UNII
D859Q6K2XE
Created by admin on Wed Apr 02 21:08:04 GMT 2025 , Edited by admin on Wed Apr 02 21:08:04 GMT 2025
PRIMARY
CAS
2744274-17-5
Created by admin on Wed Apr 02 21:08:04 GMT 2025 , Edited by admin on Wed Apr 02 21:08:04 GMT 2025
PRIMARY
From To
1_22 1_96
2_22 2_96
2_146 2_202
2_222 4_215
2_263 2_323
1_146 1_202
2_369 2_427
3_23 3_89
3_135 3_195
4_23 4_89
4_135 4_195
1_222 3_215
1_228 2_228
1_231 2_231
1_263 1_323
1_369 1_427
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_299
N 2_299
Related Record Type Details
INTERLEUKIN-1 RECEPTOR-LIKE 2
TARGET->LIGAND
Related Record Type Details
Recibokibart
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO_ACID_SUBSTITUTION [1_1] [2_1] N-TERMINUS Q PIDOLIC ACID SZB83O1W42
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
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