GAROMEFRINE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C9H13FN2O3S
Molecular Weight	248.275
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CS(=O)(=O)NC1=CC([C@@H](O)CN)=C(F)C=C1

InChI

InChIKey=XYLJNMCMDOOJRW-VIFPVBQESA-N

InChI=1S/C9H13FN2O3S/c1-16(14,15)12-6-2-3-8(10)7(4-6)9(13)5-11/h2-4,9,12-13H,5,11H2,1H3/t9-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C9H13FN2O3S
Molecular Weight	248.275
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/8719417 | https://adisinsight.springer.com/drugs/800005693

Garomefrine (NS-49) is a partial agonist of 1a-adrenoreceptor, selective with respect to other alpha 1 adrenoreceptors. It was developed by Nippon Shinyaku and investigated in clinical trials for the treatment of urinary incontinence in Japan, Europe, and the USA.

Approval Year

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:31:36 GMT 2025` Edited by `admin` on `Mon Mar 31 21:31:36 GMT 2025`
Record UNII	D62L7OV01X
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GAROMEFRINE

Common Name

English

(-)-GAROMEFRIN

Preferred Name

English

METHANESULFONAMIDE, N-(3-((1R)-2-AMINO-1-HYDROXYETHYL)-4-FLUOROPHENYL)-

Systematic Name

English

GAROMEFRIN, (-)-

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID90929796