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Details

Stereochemistry ABSOLUTE
Molecular Formula C9H13FN2O3S.ClH
Molecular Weight 284.735
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GAROMEFRINE HYDROCHLORIDE

SMILES

Cl.CS(=O)(=O)NC1=CC=C(F)C(=C1)[C@@H](O)CN

InChI

InChIKey=NYBZUGIMUSJVGU-FVGYRXGTSA-N
InChI=1S/C9H13FN2O3S.ClH/c1-16(14,15)12-6-2-3-8(10)7(4-6)9(13)5-11;/h2-4,9,12-13H,5,11H2,1H3;1H/t9-;/m0./s1

HIDE SMILES / InChI
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C9H13FN2O3S
Molecular Weight 248.275
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Garomefrine (NS-49) is a partial agonist of 1a-adrenoreceptor, selective with respect to other alpha 1 adrenoreceptors. It was developed by Nippon Shinyaku and investigated in clinical trials for the treatment of urinary incontinence in Japan, Europe, and the USA.

Approval Year

Unknown
139594
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:33:48 GMT 2023
Edited
by admin
on Fri Dec 15 16:33:48 GMT 2023
Record UNII
6GS0T2F4ZR
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
GAROMEFRINE HYDROCHLORIDE
JAN  
Common Name English
METHANESULFONAMIDE, N-(3-((1R)-2-AMINO-1-HYDROXYETHYL)-4-FLUOROPHENYL)-, MONOHYDROCHLORIDE
Common Name English
GAROMEFRIN HYDROCHLORIDE, (-)-
Common Name English
GAROMEFRIN MONOHYDROCHLORIDE
Common Name English
(-)-GAROMEFRIN HYDROCHLORIDE
Common Name English
PNO-49B
Common Name English
METHANESULFONAMIDE, N-(3-(2-AMINO-1-HYDROXYETHYL)-4-FLUOROPHENYL)-, MONOHYDROCHLORIDE, (R)-
Common Name English
((R)-(-)-3'-(2-AMINO-1-HYDROXYETHYL)-4'-FLUORO-METHANESULFONANILIDE HYDROCHLORIDE
Common Name English
METHANESULFONAMIDE, N-(3-((1R)-2-AMINO-1-HYDROXYETHYL)-4-FLUOROPHENYL)-, HYDROCHLORIDE (1:1)
Systematic Name English
ABT-232
Code English
GAROMEFRINE HYDROCHLORIDE [JAN]
Common Name English
NS-49
Common Name English
Code System Code Type Description
CHEBI
167680
Created by admin on Fri Dec 15 16:33:49 GMT 2023 , Edited by admin on Fri Dec 15 16:33:49 GMT 2023
PRIMARY
PUBCHEM
9838762
Created by admin on Fri Dec 15 16:33:49 GMT 2023 , Edited by admin on Fri Dec 15 16:33:49 GMT 2023
PRIMARY
CAS
137431-04-0
Created by admin on Fri Dec 15 16:33:49 GMT 2023 , Edited by admin on Fri Dec 15 16:33:49 GMT 2023
PRIMARY
EPA CompTox
DTXSID60160179
Created by admin on Fri Dec 15 16:33:49 GMT 2023 , Edited by admin on Fri Dec 15 16:33:49 GMT 2023
PRIMARY
FDA UNII
6GS0T2F4ZR
Created by admin on Fri Dec 15 16:33:49 GMT 2023 , Edited by admin on Fri Dec 15 16:33:49 GMT 2023
PRIMARY
Related Record Type Details
Structure of GAROMEFRINE
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of GAROMEFRINE
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