Tibremciclib

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C28H32F2N8
Molecular Weight	518.6041
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCN1CCN(CC2=CN=C(NC3=NC(C4=CC5=C(N=C6CCC[C@@H](C)N56)C(F)=C4)=C(F)C=N3)C=C2)CC1

InChI

InChIKey=XOJPAVACYRFOBK-GOSISDBHSA-N

InChI=1S/C28H32F2N8/c1-3-36-9-11-37(12-10-36)17-19-7-8-24(31-15-19)33-28-32-16-22(30)26(35-28)20-13-21(29)27-23(14-20)38-18(2)5-4-6-25(38)34-27/h7-8,13-16,18H,3-6,9-12,17H2,1-2H3,(H,31,32,33,35)/t18-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C28H32F2N8
Molecular Weight	518.6041
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Wed Apr 02 18:40:21 GMT 2025` Edited by `admin` on `Wed Apr 02 18:40:21 GMT 2025`
Record UNII	CRB7BT5JDQ
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Tibremciclib

Official Name

English

tibremciclib [INN]

Preferred Name

English

2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[(1R)-6-fluoro-1,2,3,4-tetrahydro-1-methylpyrido[1,2-a]benzimidazol-8-yl]-

Systematic Name

English

N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[(1R)-6-fluoro-1,2,3,4-tetrahydro-1-methylpyrido[1,2-a]benzimidazol-8-yl]-2-pyrimidinamine

Systematic Name

English

Code System Code Type Description

FDA UNII

CRB7BT5JDQ