RAVULIZUMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 20:26:13 GMT 2025` Edited by `admin` on `Tue Apr 01 20:26:13 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG2/4
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	C3VX249T6L
Record Status	`Validated (UNII)`
Record Version

Download

Related Record	Type

Name

Type

Language

RAVULIZUMAB

Official Name

English

ALXN-1210

Preferred Name

English

RAVULIZUMAB [JAN]

Common Name

English

RAVULIZUMAB [USAN]

Common Name

English

RAVULIZUMAB [MI]

Common Name

English

ravulizumab [INN]

Common Name

English

ALXN1210

Code

English

Ravulizumab [WHO-DD]

Common Name

English

IMMUNOGLOBULIN G2/G4, ANTI-(HUMAN COMPLEMENT C5) (HUMAN-MUS MUSCULUS ALXN1210 HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS ALXN1210 .KAPPA.-CHAIN, DIMER

Common Name

English

Classification Tree Code System Code

NDF-RT

N0000175575

Created by admin on Tue Apr 01 20:26:13 GMT 2025 , Edited by admin on Tue Apr 01 20:26:13 GMT 2025

NCI_THESAURUS

C308

Created by admin on Tue Apr 01 20:26:13 GMT 2025 , Edited by admin on Tue Apr 01 20:26:13 GMT 2025

FDA ORPHAN DRUG

513015

Created by admin on Tue Apr 01 20:26:13 GMT 2025 , Edited by admin on Tue Apr 01 20:26:13 GMT 2025

FDA ORPHAN DRUG

783320

Created by admin on Tue Apr 01 20:26:13 GMT 2025 , Edited by admin on Tue Apr 01 20:26:13 GMT 2025

FDA ORPHAN DRUG

606917

Created by admin on Tue Apr 01 20:26:13 GMT 2025 , Edited by admin on Tue Apr 01 20:26:13 GMT 2025

Code System Code Type Description

NCI_THESAURUS

C124657

Created by admin on Tue Apr 01 20:26:13 GMT 2025 , Edited by admin on Tue Apr 01 20:26:13 GMT 2025

PRIMARY

FDA UNII

C3VX249T6L

Created by admin on Tue Apr 01 20:26:13 GMT 2025 , Edited by admin on Tue Apr 01 20:26:13 GMT 2025

PRIMARY

INN

10659

Created by admin on Tue Apr 01 20:26:13 GMT 2025 , Edited by admin on Tue Apr 01 20:26:13 GMT 2025

PRIMARY

CAS

1803171-55-2

Created by admin on Tue Apr 01 20:26:13 GMT 2025 , Edited by admin on Tue Apr 01 20:26:13 GMT 2025

PRIMARY

SMS_ID

100000177402

Created by admin on Tue Apr 01 20:26:13 GMT 2025 , Edited by admin on Tue Apr 01 20:26:13 GMT 2025

PRIMARY

MERCK INDEX

m12119

Created by admin on Tue Apr 01 20:26:13 GMT 2025 , Edited by admin on Tue Apr 01 20:26:13 GMT 2025

PRIMARY

LACTMED

Ravulizumab

Created by admin on Tue Apr 01 20:26:13 GMT 2025 , Edited by admin on Tue Apr 01 20:26:13 GMT 2025

PRIMARY

USAN

DE-132

Created by admin on Tue Apr 01 20:26:13 GMT 2025 , Edited by admin on Tue Apr 01 20:26:13 GMT 2025

PRIMARY

DRUG CENTRAL

5322

Created by admin on Tue Apr 01 20:26:13 GMT 2025 , Edited by admin on Tue Apr 01 20:26:13 GMT 2025

PRIMARY

RXCUI

2107301

Created by admin on Tue Apr 01 20:26:13 GMT 2025 , Edited by admin on Tue Apr 01 20:26:13 GMT 2025

PRIMARY

DAILYMED

C3VX249T6L

Created by admin on Tue Apr 01 20:26:13 GMT 2025 , Edited by admin on Tue Apr 01 20:26:13 GMT 2025

PRIMARY

RXCUI

2107316

Created by admin on Tue Apr 01 20:26:13 GMT 2025 , Edited by admin on Tue Apr 01 20:26:13 GMT 2025

ALTERNATIVE

WIKIPEDIA

Ravulizumab

Created by admin on Tue Apr 01 20:26:13 GMT 2025 , Edited by admin on Tue Apr 01 20:26:13 GMT 2025

PRIMARY

DRUG BANK

DB11580

Created by admin on Tue Apr 01 20:26:13 GMT 2025 , Edited by admin on Tue Apr 01 20:26:13 GMT 2025

PRIMARY

From	To
1_22	1_96
1_136	3_214
1_149	1_205
1_224	2_224
1_225	2_225
1_228	2_228
1_231	2_231
1_262	1_322
1_368	1_426
2_22	2_96
2_136	4_214
2_149	2_205
2_262	2_322
2_368	2_426
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194

Glycosylation Link Type	Site
N	1_298
N	2_298

Related Record Type Details

RAVULIZUMAB-CWVZ

INNOVATOR->PARENT

Amount:

RAVULIZUMAB-CWVZ

SUB_CONCEPT->SUBSTANCE

Amount:


					7A6G4V3R84

TARGET -> INHIBITOR

Related Record Type Details


					C3VX249T6L

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_1] [2_1]				PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL