Olomorasib

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C25H19ClF2N4O3S
Molecular Weight	528.958
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0
Stereo Comments	AXIAL R (M helicity)

SHOW SMILES / InChI

Structure Search

SMILES

NC1=C(C#N)C2=C(C=CC(F)=C2S1)C3=C(F)C=C4C(OCC[C@H]5CN(CCN5C4=O)C(=O)C=C)=C3Cl

InChI

InChIKey=OZUPICRWMLEFCS-LBPRGKRZSA-N

InChI=1S/C25H19ClF2N4O3S/c1-2-18(33)31-6-7-32-12(11-31)5-8-35-22-14(25(32)34)9-17(28)20(21(22)26)13-3-4-16(27)23-19(13)15(10-29)24(30)36-23/h2-4,9,12H,1,5-8,11,30H2/t12-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C25H19ClF2N4O3S
Molecular Weight	528.958
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Wed Apr 02 11:40:02 GMT 2025` Edited by `admin` on `Wed Apr 02 11:40:02 GMT 2025`
Record UNII	C2VJ83PSN7
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Olomorasib

Official Name

English

Benzo[b]thiophene-3-carbonitrile, 2-amino-4-[(4aS)-8-chloro-10-fluoro-2,3,4,4a,5,6-hexahydro-12-oxo-3-(1-oxo-2-propen-1-yl)-1H,12H-pyrazino[2,1-d][1,5]benzoxazocin-9-yl]-7-fluoro-, (4R)-

Preferred Name

English

LY3537982

Code

English

OLOMORASIB [USAN]

Common Name

English

LY-3537982

Code

English

olomorasib [INN]

Common Name

English

(4R)-2-Amino-4-[(4aS)-8-chloro-10-fluoro-2,3,4,4a,5,6-hexahydro-12-oxo-3-(1-oxo-2-propen-1-yl)-1H,12H-pyrazino[2,1-d][1,5]benzoxazocin-9-yl]-7-fluorobenzo[b]thiophene-3-carbonitrile

Systematic Name

English

2-Amino-4-[(4R)-8-chloro-10-fluoro-12-oxo-3-(prop-2-enoyl)-2,3,4,4a,5,6-hexahydro-1H,12H-pyrazino[2,1-d][1,5]benzoxazocin-9-yl]-7-fluoro-1-benzothiophene-3-carbonitrile

Systematic Name

English

Code System Code Type Description

INN

13077