Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C18H21NO2 |
| Molecular Weight | 283.3648 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC(=O)C1=CC(CCN(C)CC2=CC=CC=C2)=CC=C1
InChI
InChIKey=IGJQEMHBYKNIQR-UHFFFAOYSA-N
InChI=1S/C18H21NO2/c1-19(14-16-7-4-3-5-8-16)12-11-15-9-6-10-17(13-15)18(20)21-2/h3-10,13H,11-12,14H2,1-2H3
| Molecular Formula | C18H21NO2 |
| Molecular Weight | 283.3648 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 17:24:11 UTC 2023
by
admin
on
Fri Dec 15 17:24:11 UTC 2023
|
| Record UNII |
BM2TE2XHK6
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Common Name | English | ||
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Systematic Name | English | ||
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Common Name | English | ||
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Code | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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39989
Created by
admin on Fri Dec 15 17:24:11 UTC 2023 , Edited by admin on Fri Dec 15 17:24:11 UTC 2023
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PRIMARY | |||
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BM2TE2XHK6
Created by
admin on Fri Dec 15 17:24:11 UTC 2023 , Edited by admin on Fri Dec 15 17:24:11 UTC 2023
|
PRIMARY | |||
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PRL-8-53
Created by
admin on Fri Dec 15 17:24:11 UTC 2023 , Edited by admin on Fri Dec 15 17:24:11 UTC 2023
|
PRIMARY | PRL-8-53 is relatively non-toxic, with an oral LD50 in mice of 860 mg/kg, giving the drug a high therapeutic index. Doses above 8 mg/kg have brief hypotensive effects in the canine. High doses depress motor activity in the rat and mouse, with the ED50 for a 50% reduction in motor activity of mice at 160 mg/kg. PRL-8-53 displays spasmolytic effects. | ||
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DTXSID701045345
Created by
admin on Fri Dec 15 17:24:11 UTC 2023 , Edited by admin on Fri Dec 15 17:24:11 UTC 2023
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PRIMARY | |||
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51352-88-6
Created by
admin on Fri Dec 15 17:24:11 UTC 2023 , Edited by admin on Fri Dec 15 17:24:11 UTC 2023
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PRIMARY | |||
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PRL-8-53
Created by
admin on Fri Dec 15 17:24:11 UTC 2023 , Edited by admin on Fri Dec 15 17:24:11 UTC 2023
|
PRIMARY | The only human study on PRL-8-53 was based on the ingestion of a single 5 mg dose. There is no data on the effectiveness or potential toxicity of any other dosage in humans. |
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SALT/SOLVATE -> PARENT | |||
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PARENT -> DERIVATIVE |
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PARENT -> DERIVATIVE |
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| Related Record | Type | Details | ||
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ACTIVE MOIETY |
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