ANDEXANET ALFA

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 11:05:15 GMT 2023` Edited by `admin` on `Sat Dec 16 11:05:15 GMT 2023`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	BI009E452R
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ANDEXANET ALFA

Official Name

English

PRT064445

Code

English

PRT-064445

Code

English

COAGULATION FACTOR XA (RECOMBINANT), INACTIVATED-ZHZO

Official Name

English

ANDEXANET ALFA [USAN]

Common Name

English

DES-(6-39)-HUMAN BLOOD-COAGULATION FACTOR X LIGHT CHAIN (98-108')- DISULFIDE WITH (185'-ALANINE (S>A))HUMAN ACTIVATED FACTOR XA HEAVY CHAIN, PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS (GLYCOFORM ALFA)

Systematic Name

English

ANDEXXA

Brand Name

English

ANDEXANET ALFA [JAN]

Common Name

English

andexanet alfa [INN]

Common Name

English

PRT-4445

Code

English

RFXA INHIBITOR ANTIDOTE

Code

English

Andexanet alfa [WHO-DD]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

437414

Created by admin on Sat Dec 16 11:05:15 GMT 2023 , Edited by admin on Sat Dec 16 11:05:15 GMT 2023

WHO-ATC

V03AB38

Created by admin on Sat Dec 16 11:05:15 GMT 2023 , Edited by admin on Sat Dec 16 11:05:15 GMT 2023

Code System Code Type Description

SMS_ID

100000166815

Created by admin on Sat Dec 16 11:05:15 GMT 2023 , Edited by admin on Sat Dec 16 11:05:15 GMT 2023

PRIMARY

DAILYMED

BI009E452R

Created by admin on Sat Dec 16 11:05:15 GMT 2023 , Edited by admin on Sat Dec 16 11:05:15 GMT 2023

PRIMARY

USAN

BC-65

Created by admin on Sat Dec 16 11:05:15 GMT 2023 , Edited by admin on Sat Dec 16 11:05:15 GMT 2023

PRIMARY

RXCUI

2045114

Created by admin on Sat Dec 16 11:05:15 GMT 2023 , Edited by admin on Sat Dec 16 11:05:15 GMT 2023

PRIMARY

FDA UNII

BI009E452R

Created by admin on Sat Dec 16 11:05:15 GMT 2023 , Edited by admin on Sat Dec 16 11:05:15 GMT 2023

PRIMARY

NCI_THESAURUS

C171753

Created by admin on Sat Dec 16 11:05:15 GMT 2023 , Edited by admin on Sat Dec 16 11:05:15 GMT 2023

PRIMARY

ChEMBL

CHEMBL3301583

Created by admin on Sat Dec 16 11:05:15 GMT 2023 , Edited by admin on Sat Dec 16 11:05:15 GMT 2023

PRIMARY

DRUG BANK

DB14562

Created by admin on Sat Dec 16 11:05:15 GMT 2023 , Edited by admin on Sat Dec 16 11:05:15 GMT 2023

PRIMARY

DRUG CENTRAL

5336

Created by admin on Sat Dec 16 11:05:15 GMT 2023 , Edited by admin on Sat Dec 16 11:05:15 GMT 2023

PRIMARY

EVMPD

SUB181082

Created by admin on Sat Dec 16 11:05:15 GMT 2023 , Edited by admin on Sat Dec 16 11:05:15 GMT 2023

PRIMARY

RXCUI

2045125

Created by admin on Sat Dec 16 11:05:15 GMT 2023 , Edited by admin on Sat Dec 16 11:05:15 GMT 2023

ALTERNATIVE

INN

9883

Created by admin on Sat Dec 16 11:05:15 GMT 2023 , Edited by admin on Sat Dec 16 11:05:15 GMT 2023

PRIMARY

WIKIPEDIA

Andexanet alfa

Created by admin on Sat Dec 16 11:05:15 GMT 2023 , Edited by admin on Sat Dec 16 11:05:15 GMT 2023

PRIMARY

CAS

1262449-58-0

Created by admin on Sat Dec 16 11:05:15 GMT 2023 , Edited by admin on Sat Dec 16 11:05:15 GMT 2023

PRIMARY

From	To
1_7	1_12
1_27	1_43
1_108	2_98
1_156	1_170
1_181	1_209
2_16	2_27
2_21	2_36
2_38	2_47
2_55	2_66
2_62	2_75
2_77	2_90

Glycosylation Link Type	Site
O	1_82
O	1_249
O	2_56
O	2_72

Related Record Type Details


					BI009E452R

ACTIVE MOIETY

Comments:

PRT064445 has high affinity for small molecule fXa inhibitors

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL