Stereochemistry | ACHIRAL |
Molecular Formula | C16H20N2O4S2 |
Molecular Weight | 368.471 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=NC=C(CSSCC2=CN=C(C)C(O)=C2CO)C(CO)=C1O
InChI
InChIKey=SIXLXDIJGIWWFU-UHFFFAOYSA-N
InChI=1S/C16H20N2O4S2/c1-9-15(21)13(5-19)11(3-17-9)7-23-24-8-12-4-18-10(2)16(22)14(12)6-20/h3-4,19-22H,5-8H2,1-2H3
Molecular Formula | C16H20N2O4S2 |
Molecular Weight | 368.471 |
Charge | 0 |
Count |
MOL RATIO
1 MOL RATIO (average) |
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Pyritinol is a semi natural analogue of water soluble vitamin B6. Pyritinol was synthetized way back in 1961 by Merck Laboratories. After years of research, it entered the market in the 1970s, where it was used for clinical applications – including treating stroke patients and those with Alzheimer’s. Since the 1990s, it has been sold as a nootropic dietary supplement in the United States and many other parts of the world. Pyritinol, unlike many other nootropics, has been approved for use as a medical treatment in countries around the world. Doctors in many European countries use Pyritinol to treat patients with chronic degenerative brain disorders – like dementia. Countries where Pyritinol is an approved treatment include Austria, Germany, France, Greece, Italy, and Portugal. France has approved the use of Pyritinol – but only as a treatment for rheumatoid arthritis. Pyritinol is not currently licensed for use in the United Kingdom, but in most other countries, it’s available online or through drug stores as an over the counter substance. Pyritinol is marketed under the brand names Encephabol, Encefabol and Cerbon 6. One of the known mechanisms of action of Pyritinol involves increasing choline uptake into your neurons and thereby increasing acetylcholine levels. Pyritinol is also a great effective precursor to dopamine, which is one of the neurotransmitter mood-boosters in the brain. Pyritinol has better conversion into the neurochemical. This drug increases dopamine, which can keep the brain from anxiety because a lower dopamine level is connected to mood disorders and depression.
CNS Activity
Originator
Approval Year
Doses
AEs
PubMed
Patents
Sample Use Guides
Encephabol (Pyritinol) comes in coated tablets.
The dosage depends on the severity of the patients condition.
Tablets should be taken with meal and a large glass of water.
Dosage for adults: 600 mg a day (2 tabs 3 times a day).
Dosage for newborn infants: on the third day of life 20 mg a day during a month.
Dosage for pediatric patients: 2 months: the dosage is increases 20 mg every next week until the daily dose will be 100 mg.
1-7 years old: 50-300 mg a day.
7 years old and over: 50-600 mg a day (1-2 tabs 1-3 times a day).
In patients with chronic conditions the period of therapy should be no less than 8 weeks.
Route of Administration:
Oral