U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

1999
175
Substance Class Protein
Created
by admin
on Mon Mar 31 20:48:24 GMT 2025
Edited
by admin
on Mon Mar 31 20:48:24 GMT 2025
Protein Type COAGULATION FACTOR
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
AC71R787OV
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
COAGULATION FACTOR VIIA RECOMBINANT HUMAN
Common Name English
EPTACOG ALFA (ACTIVATED)
EMA EPAR   INN   MART.   WHO-DD  
INN  
Preferred Name English
eptacog alfa (activated) [INN]
Common Name English
COAGULATION FACTOR VIIA (RECOMBINANT)
Common Name English
Eptacog alfa (activated) [WHO-DD]
Common Name English
Factor viia, recombinant [WHO-DD]
Common Name English
COAGULATION FACTOR VIIA RECOMBINANT
Common Name English
EPTACOG ALFA (ACTIVATED) [EMA EPAR]
Common Name English
ACTIVATED RECOMBINANT HUMAN FACTOR VII
Common Name English
BLOOD-COAGULATION FACTOR VII (HUMAN CLONE LHVII2463 PROTEIN MOIETY)
Common Name English
NOVOSEVEN
Brand Name English
NIASTASE
Brand Name English
NOVOSEVEN RT
Brand Name English
RECOMBINANT COAGULATION FACTOR VIIA
Common Name English
RECOMBINANT FVIIA
Common Name English
BLOOD-COAGULATION FACTOR VII (HUMAN CLONE .LAMBDA.HVII2463 PROTEIN MOIETY)
Common Name English
EPTACOG ALFA
Common Name English
EPTACOG ALFA (ACTIVATED) [JAN]
Common Name English
EPTACOG ALFA (ACTIVATED) [MART.]
Common Name English
FACTOR VIIA,RECOMBINANT [VANDF]
Common Name English
RECOMBINANT ACTIVATED FACTOR VII
Common Name English
EPTACOG ALFA ACTIVATED
Common Name English
Classification Tree Code System Code
WHO-VATC QB02BD08
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
NDF-RT N0000184169
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
WHO-ATC B02BD08
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
FDA ORPHAN DRUG 185904
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
EMA ASSESSMENT REPORTS NOVOSEVEN (AUTHORIZED: HEMOPHILIA B)
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
FDA ORPHAN DRUG 192404
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
FDA ORPHAN DRUG 186004
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
NDF-RT N0000184169
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
EMA ASSESSMENT REPORTS NOVOSEVEN (AUTHORIZED: FACTOR VII DEFICIENCY)
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
EMA ASSESSMENT REPORTS NOVOSEVEN (AUTHORIZED: THROMBASTHENIA)
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
FDA ORPHAN DRUG 186104
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
EU-Orphan Drug EU/3/07/436
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
FDA ORPHAN DRUG 190104
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
FDA ORPHAN DRUG 190004
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
FDA ORPHAN DRUG 189904
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
FDA ORPHAN DRUG 26588
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
FDA ORPHAN DRUG 213005
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
FDA ORPHAN DRUG 186204
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
Code System Code Type Description
DAILYMED
AC71R787OV
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
PRIMARY
CAS
1228539-24-9
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
ALTERNATIVE
INN
10042
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
ALTERNATIVE
NDF-RT
N0000007914
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
PRIMARY Blood Coagulation Factors [Chemical/Ingredient]
NDF-RT
N0000184153
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
PRIMARY Increased Coagulation Factor IX Activity [PE]
DRUG BANK
DB00036
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
PRIMARY
EVMPD
SUB06591MIG
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
PRIMARY
NDF-RT
N0000184154
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
PRIMARY Increased Coagulation Factor X Activity [PE]
DRUG CENTRAL
5159
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
PRIMARY
RXCUI
314620
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
ALTERNATIVE
ChEMBL
CHEMBL2108334
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
PRIMARY
FDA UNII
AC71R787OV
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
PRIMARY
RS_ITEM_NUM
1311500
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
PRIMARY
RXCUI
253149
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
PRIMARY
NCI_THESAURUS
C81125
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
PRIMARY
WIKIPEDIA
Recombinant factor VIIa
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
PRIMARY
MESH
C103587
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
PRIMARY
INN
6931
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
PRIMARY
CAS
102786-61-8
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
PRIMARY
ChEMBL
CHEMBL2108405
Created by admin on Mon Mar 31 20:48:24 GMT 2025 , Edited by admin on Mon Mar 31 20:48:24 GMT 2025
PRIMARY
From To
1_7 1_12
1_26 1_42
1_158 1_177
1_188 1_216
2_17 2_22
2_50 2_61
2_55 2_70
2_72 2_81
2_91 2_102
2_98 2_112
2_114 2_127
1_110 2_135
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_170
N 2_145
O 2_52
O 2_60
Related Record Type Details
EPTACOG ALFA PEGOL (ACTIVATED)
INGREDIENT -> STARTING MATERIAL
COAGULATION FACTOR VIIA (RECOMBINANT)-JNCW
SUB_CONCEPT->SUBSTANCE
Related Record Type Details
COAGULATION FACTOR VIIA RECOMBINANT HUMAN
ACTIVE MOIETY
COAGULATION FACTOR VIIA RECOMBINANT HUMAN
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO_ACID_SUBSTITUTION [2_63] SITE_SPECIFIC ASP .BETA.-HYDROXY-L-ASPARTIC ACID, ERYTHRO- GDV0MSK2SG
AMINO_ACID_SUBSTITUTION [2_6] [2_7] [2_14] [2_16] [2_19] [2_20] [2_25] [2_26] [2_29] [2_35] SITE_SPECIFIC GLU .GAMMA.-CARBOXYGLUTAMIC ACID 16FQV4RZKL
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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