EPTACOG ALFA PEGOL (ACTIVATED)

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NCATS

Investigational

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 21:28:19 GMT 2025` Edited by `admin` on `Mon Mar 31 21:28:19 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	3Q26I70P3I
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ACTIVATED RECOMBINANT HUMAN FACTOR VII, LONG ACTING

Preferred Name

English

EPTACOG ALFA PEGOL (ACTIVATED)

Official Name

English

eptacog alfa pegol (activated) [INN]

Common Name

English

BLOOD-COAGULATION FACTOR VII (SYNTHETIC HUMAN), 40-KILODALTON PEGYLATED

Common Name

English

Eptacog alfa pegol (activated) [WHO-DD]

Common Name

English

Code System Code Type Description

ChEMBL

CHEMBL2108292

Created by admin on Mon Mar 31 21:28:19 GMT 2025 , Edited by admin on Mon Mar 31 21:28:19 GMT 2025

PRIMARY

SMS_ID

300000006103

Created by admin on Mon Mar 31 21:28:19 GMT 2025 , Edited by admin on Mon Mar 31 21:28:19 GMT 2025

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CAS

944130-77-2

Created by admin on Mon Mar 31 21:28:19 GMT 2025 , Edited by admin on Mon Mar 31 21:28:19 GMT 2025

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INN

9027

Created by admin on Mon Mar 31 21:28:19 GMT 2025 , Edited by admin on Mon Mar 31 21:28:19 GMT 2025

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NCI_THESAURUS

C166689

Created by admin on Mon Mar 31 21:28:19 GMT 2025 , Edited by admin on Mon Mar 31 21:28:19 GMT 2025

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FDA UNII

3Q26I70P3I

Created by admin on Mon Mar 31 21:28:19 GMT 2025 , Edited by admin on Mon Mar 31 21:28:19 GMT 2025

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DRUG BANK

DB11661

Created by admin on Mon Mar 31 21:28:19 GMT 2025 , Edited by admin on Mon Mar 31 21:28:19 GMT 2025

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From	To
1_7	1_12
1_26	1_42
1_158	1_177
1_188	1_216
2_17	2_22
2_50	2_61
2_55	2_70
2_91	2_102
2_98	2_112
2_114	2_127

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_170
N	2_145
O	2_52
O	2_60

Related Record Type Details


					AC71R787OV

COAGULATION FACTOR VIIA RECOMBINANT HUMAN

STARTING MATERIAL -> INGREDIENT

Amount:

Agent Modifications

Modification Process	Modification Role	Modification Type	Amount	Fragment Name	Fragment ID
PEGYLATION	PEGYLATION	CHEMICAL		MPEG 40000 PHOSPHORIC ACID	B59V4U5H37

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
ENZYMATIC 3R-HYDROXYLATION	[2_63]		ASP		.BETA.-HYDROXY-L-ASPARTIC ACID, ERYTHRO-	GDV0MSK2SG
ENZYMATIC GAMMA-CARBOXYLATION	[2_6] [2_7] [2_14] [2_16] [2_19] [2_20] [2_25] [2_26] [2_29] [2_35]		GLU		.GAMMA.-CARBOXYGLUTAMIC ACID	16FQV4RZKL

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(ESTIMATED)	CHEMICAL