MOPROLOL

Details

Stereochemistry	RACEMIC
Molecular Formula	C13H21NO3
Molecular Weight	239.3107
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=C(OCC(O)CNC(C)C)C=CC=C1

InChI

InChIKey=LFTFGCDECFPSQD-UHFFFAOYSA-N

InChI=1S/C13H21NO3/c1-10(2)14-8-11(15)9-17-13-7-5-4-6-12(13)16-3/h4-7,10-11,14-15H,8-9H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C13H21NO3
Molecular Weight	239.3107
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/36116 | https://www.ncbi.nlm.nih.gov/pubmed/6120901

Moprolol is a beta-adrenergic antagonist, or beta blocker, typically prescribed to treat hypertension, high blood pressure, angina pectoris, arrhythmias, anxiety, and glaucoma. Moprolol has been the subject for many clinical trials to study the effect moprolol has on both blood pressure and glaucoma. In clinical trials, Moprolol shows some effect on lowering blood pressure with no effects on the heart rate. Moprolol is currently off the market, most likely due to the manufacturer being in violation of US good manufacturing practices.

Originator

Approval Year

PubMed

Title	Date	PubMed
[Evaluation of the effects of a beta-blocking drug (moprolol) on hemodynamics and lesion potentials in acute myocardial infarct].	1977	36116
[A case of giant cell microscopic colitis?].	2008 Dec	19084720

Patents

Sample Use Guides

In Vivo Use Guide

75 mg

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:58:22 GMT 2023` Edited by `admin` on `Sat Dec 16 17:58:22 GMT 2023`
Record UNII	A94HCH4225
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MOPROLOL

Official Name

English

moprolol [INN]

Common Name

English

MOPROLOL [MI]

Common Name

English

Moprolol [WHO-DD]

Common Name

English

1-(ISOPROPYLAMINO)-3-(O-METHOXYPHENOXY)-2-PROPANOL

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29576