U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C13H21NO3
Molecular Weight 239.3107
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MOPROLOL

SMILES

COC1=C(OCC(O)CNC(C)C)C=CC=C1

InChI

InChIKey=LFTFGCDECFPSQD-UHFFFAOYSA-N
InChI=1S/C13H21NO3/c1-10(2)14-8-11(15)9-17-13-7-5-4-6-12(13)16-3/h4-7,10-11,14-15H,8-9H2,1-3H3

HIDE SMILES / InChI

Molecular Formula C13H21NO3
Molecular Weight 239.3107
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Moprolol is a beta-adrenergic antagonist, or beta blocker, typically prescribed to treat hypertension, high blood pressure, angina pectoris, arrhythmias, anxiety, and glaucoma. Moprolol has been the subject for many clinical trials to study the effect moprolol has on both blood pressure and glaucoma. In clinical trials, Moprolol shows some effect on lowering blood pressure with no effects on the heart rate. Moprolol is currently off the market, most likely due to the manufacturer being in violation of US good manufacturing practices.

Approval Year

PubMed

PubMed

TitleDatePubMed
Patents

Sample Use Guides

75 mg
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Sat Dec 16 17:58:22 GMT 2023
Edited
by admin
on Sat Dec 16 17:58:22 GMT 2023
Record UNII
A94HCH4225
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MOPROLOL
INN   MI   WHO-DD  
INN  
Official Name English
moprolol [INN]
Common Name English
MOPROLOL [MI]
Common Name English
Moprolol [WHO-DD]
Common Name English
1-(ISOPROPYLAMINO)-3-(O-METHOXYPHENOXY)-2-PROPANOL
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29576
Created by admin on Sat Dec 16 17:58:22 GMT 2023 , Edited by admin on Sat Dec 16 17:58:22 GMT 2023
Code System Code Type Description
DRUG CENTRAL
1839
Created by admin on Sat Dec 16 17:58:22 GMT 2023 , Edited by admin on Sat Dec 16 17:58:22 GMT 2023
PRIMARY
EVMPD
SUB09060MIG
Created by admin on Sat Dec 16 17:58:22 GMT 2023 , Edited by admin on Sat Dec 16 17:58:22 GMT 2023
PRIMARY
WIKIPEDIA
Moprolol
Created by admin on Sat Dec 16 17:58:22 GMT 2023 , Edited by admin on Sat Dec 16 17:58:22 GMT 2023
PRIMARY
ChEMBL
CHEMBL156901
Created by admin on Sat Dec 16 17:58:22 GMT 2023 , Edited by admin on Sat Dec 16 17:58:22 GMT 2023
PRIMARY
EPA CompTox
DTXSID00863612
Created by admin on Sat Dec 16 17:58:22 GMT 2023 , Edited by admin on Sat Dec 16 17:58:22 GMT 2023
PRIMARY
INN
4024
Created by admin on Sat Dec 16 17:58:22 GMT 2023 , Edited by admin on Sat Dec 16 17:58:22 GMT 2023
PRIMARY
SMS_ID
100000080385
Created by admin on Sat Dec 16 17:58:22 GMT 2023 , Edited by admin on Sat Dec 16 17:58:22 GMT 2023
PRIMARY
ECHA (EC/EINECS)
227-254-7
Created by admin on Sat Dec 16 17:58:22 GMT 2023 , Edited by admin on Sat Dec 16 17:58:22 GMT 2023
PRIMARY
PUBCHEM
71213
Created by admin on Sat Dec 16 17:58:22 GMT 2023 , Edited by admin on Sat Dec 16 17:58:22 GMT 2023
PRIMARY
MERCK INDEX
m1207
Created by admin on Sat Dec 16 17:58:22 GMT 2023 , Edited by admin on Sat Dec 16 17:58:22 GMT 2023
PRIMARY Merck Index
CAS
5741-22-0
Created by admin on Sat Dec 16 17:58:22 GMT 2023 , Edited by admin on Sat Dec 16 17:58:22 GMT 2023
PRIMARY
NCI_THESAURUS
C90797
Created by admin on Sat Dec 16 17:58:22 GMT 2023 , Edited by admin on Sat Dec 16 17:58:22 GMT 2023
PRIMARY
FDA UNII
A94HCH4225
Created by admin on Sat Dec 16 17:58:22 GMT 2023 , Edited by admin on Sat Dec 16 17:58:22 GMT 2023
PRIMARY
MESH
C009976
Created by admin on Sat Dec 16 17:58:22 GMT 2023 , Edited by admin on Sat Dec 16 17:58:22 GMT 2023
PRIMARY
Related Record Type Details
ENANTIOMER -> RACEMATE
ENANTIOMER -> RACEMATE
Related Record Type Details
ACTIVE MOIETY