MIDAXIFYLLINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H25N5O2
Molecular Weight	319.402
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCN1C2=C(NC(=N2)C3(N)CCCC3)C(=O)N(CCC)C1=O

InChI

InChIKey=UFOBUCDTKQDDTN-UHFFFAOYSA-N

InChI=1S/C16H25N5O2/c1-3-9-20-12-11(13(22)21(10-4-2)15(20)23)18-14(19-12)16(17)7-5-6-8-16/h3-10,17H2,1-2H3,(H,18,19)

HIDE SMILES / InChI

Molecular Formula	C16H25N5O2
Molecular Weight	319.402
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://adisinsight.springer.com/drugs/800006420

Midaxifylline, a potent and selective xanthine adenosine A1 receptor antagonist, was investigated for the treatment of Alzheimer's disease, cardiovascular disorders, kidney disorders, and major depressive disorder. However, all studies were discontinued.

Originator

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:14:16 GMT 2023` Edited by `admin` on `Fri Dec 15 16:14:16 GMT 2023`
Record UNII	A937Z0MS6C
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MIDAXIFYLLINE

Official Name

English

8-(1-AMINOCYCLOPENTYL)-1,3-DIPROPYLXANTHINE

Systematic Name

English

Midaxifylline [WHO-DD]

Common Name

English

midaxifylline [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C744