U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

2007
205
Substance Class Protein
Created
by admin
on Sat Dec 16 16:22:47 GMT 2023
Edited
by admin
on Sat Dec 16 16:22:47 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG2
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
A3ULP0F556
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ECULIZUMAB
EMA EPAR   INN   MART.   MI   USAN   VANDF   WHO-DD  
USAN   INN  
Official Name English
H5G11
Code English
H5G1.1VHC+H5G1.1VLC
Code English
ECULIZUMAB [USAN]
Common Name English
ECULIZUMAB [JAN]
Common Name English
ELIZARIA
Brand Name English
ALEXION
Brand Name English
eculizumab [INN]
Common Name English
ECULIZUMAB [VANDF]
Common Name English
H5G1-1
Code English
IMMUNOGLOBULIN, ANTI-(HUMAN COMPLEMENT C5 .ALPHA.-CHAIN) (HUMAN-MOUSE MONOCLONAL 5G1.1 HEAVY CHAIN), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL 5G.1.1 LIGHT CHAIN, DIMER
Systematic Name English
ECULIZUMAB [EMA EPAR]
Common Name English
ECULIZUMAB [PURPLE BOOK CDER]
Common Name English
ECULIZUMAB [MI]
Common Name English
ECULIZUMAB [MART.]
Common Name English
SOLIRIS
Brand Name English
Eculizumab [WHO-DD]
Common Name English
5G1.1
Code English
H5G1.1
Code English
Classification Tree Code System Code
NCI_THESAURUS C20401
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
FDA ORPHAN DRUG 138800
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
FDA ORPHAN DRUG 434214
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
FDA ORPHAN DRUG 539416
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
NDF-RT N0000175974
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
FDA ORPHAN DRUG 398713
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
NDF-RT N0000175575
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
FDA ORPHAN DRUG 136100
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
EMA ASSESSMENT REPORTS SOLIRIS (AUTHORIZED: HEMOGLOBINURIA, PAROXYSMAL)
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
FDA ORPHAN DRUG 902222
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
FDA ORPHAN DRUG 173203
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
WHO-VATC QL04AA25
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
FDA ORPHAN DRUG 417213
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
FDA ORPHAN DRUG 279509
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
WHO-ATC L04AA25
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
FDA ORPHAN DRUG 354511
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
EU-Orphan Drug EU/3/14/1238
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
Code System Code Type Description
INN
8231
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
PRIMARY
LACTMED
Eculizumab
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
PRIMARY
IUPHAR
6884
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
PRIMARY
SMS_ID
100000089131
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
PRIMARY
NCI_THESAURUS
C48386
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
PRIMARY
CAS
219685-50-4
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
PRIMARY
DAILYMED
A3ULP0F556
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
PRIMARY
FDA UNII
A3ULP0F556
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
PRIMARY
MESH
C481642
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
PRIMARY
DRUG BANK
DB01257
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
PRIMARY
USAN
LL-70
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
PRIMARY
ChEMBL
CHEMBL1201828
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
PRIMARY
DRUG CENTRAL
4969
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
PRIMARY
WIKIPEDIA
ECULIZUMAB
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
PRIMARY
RXCUI
591781
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
PRIMARY RxNorm
EVMPD
SUB25187
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
PRIMARY
MERCK INDEX
m4823
Created by admin on Sat Dec 16 16:22:47 GMT 2023 , Edited by admin on Sat Dec 16 16:22:47 GMT 2023
PRIMARY Merck Index
From To
1_22 1_96
1_136 3_214
1_149 1_205
1_228 2_228
1_231 2_231
1_262 1_322
1_368 1_426
2_22 2_96
2_136 4_214
2_149 2_205
2_262 2_322
2_368 2_426
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_298
N 2_298
Related Record Type Details
COMPLEMENT C5
TARGET -> INHIBITOR
Related Record Type Details
ECULIZUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC
Molecular Formula CHEMICAL
MOL_WEIGHT:ESTIMATED CHEMICAL
Volume of Distribution PHARMACOKINETIC
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966