Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | 4C2H5NO2.I2.2HI |
| Molecular Weight | 809.9002 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
I.I.II.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O
InChI
InChIKey=GRSBODOCWBNPOF-UHFFFAOYSA-N
InChI=1S/4C2H5NO2.I2.2HI/c4*3-1-2(4)5;1-2;;/h4*1,3H2,(H,4,5);;2*1H
| Molecular Formula | HI |
| Molecular Weight | 127.91241 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C2H5NO2 |
| Molecular Weight | 75.0666 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | I2 |
| Molecular Weight | 253.80894 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Tetraglycine hydroperiodide is an iodine-containing chemical, used for water purification. Tetraglycine hydroperiodide is marketed in tablets; each tablet effectively disinfects 1 liter of clear water or 0.5 liter of tainted water by releasing approximately 8 mg free iodine. It requires approximately 30 minutes to inactivate target microorganisms and make water bacteriologically suitable for drinking. To remove iodine taste, a vitamin C pill is added to the kit.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Developmental iodine deficiency delays the maturation of newborn granule neurons associated with downregulation of p35 in postnatal rat hippocampus. | 2014-08 |
|
| Sensitivity of human dental pulp cells to eighteen chemical agents used for endodontic treatments in dentistry. | 2013-01 |
|
| Opposing regulation of cytochrome P450 expression by CAR and PXR in hypothyroid mice. | 2012-09-01 |
|
| The effects of ammonium perchlorate on thyroid homeostasis and thyroid-specific gene expression in rat. | 2012-08 |
|
| A blinded, randomized, palatability study comparing variations of 2 popular field water disinfection tablets. | 2011-12 |
|
| I-131 dose response for incident thyroid cancers in Ukraine related to the Chornobyl accident. | 2011-07 |
|
| Use of gadolinium for carotid artery angiography and stenting in patients with renal insufficiency. | 2009-12 |
|
| [The effects of iodine/selenium on the function of antigen presentation of peritoneal macrophages in rats]. | 2008-07 |
|
| Gadolinium and kidney disease: are your patients at risk? | 2008-05-14 |
|
| [Suggestions for prevention of adverse reactions after intravasal administration of iodinated contrast media]. | 2008 |
|
| Increased iodine uptake in thyroid carcinoma after treatment with sodium butyrate and decitabine (5-Aza-dC). | 2007-11 |
|
| Comparison of the usefulness of gadodiamide and iodine mixture versus iodinated contrast alone for prevention of contrast-induced nephropathy in patients with chronic kidney disease undergoing coronary angiography. | 2007-10-01 |
|
| Sodium iodide symporter is expressed at the preneoplastic stages of liver carcinogenesis and in human cholangiocarcinoma. | 2007-04 |
|
| [Effects of iodine excess and selenium supplement on the levels of thyroid hormone and its receptor expression in filial cerebrum of mice]. | 2007-03 |
|
| Enhanced expression of adenovirus-mediated sodium iodide symporter gene in MCF-7 breast cancer cells with retinoic acid treatment. | 2007-03 |
|
| Goiter and other iodine deficiency disorders: A systematic review of epidemiological studies to deconstruct the complex web. | 2007-01 |
|
| Comparative cytotoxicity of high-osmolar and low-osmolar contrast media on HKCs in vitro. | 2006-12-19 |
|
| Antiseptics, iodine, povidone iodine and traumatic wound cleansing. | 2006-11 |
|
| The treatment of Graves' disease in children. | 2006-09 |
|
| Synergistic regulation of endothelial tight junctions by antioxidant (Se) and polyunsaturated lipid (GLA) via Claudin-5 modulation. | 2006-08-01 |
|
| Effect of selenium supplementation on activity and mRNA expression of type 1 deiodinase in mice with excessive iodine intake. | 2006-08 |
|
| Molecular iodine induces caspase-independent apoptosis in human breast carcinoma cells involving the mitochondria-mediated pathway. | 2006-07-14 |
|
| Salt dual-fortified with iodine and micronized ground ferric pyrophosphate affects iron status but not hemoglobin in children in Cote d'Ivoire. | 2006-07 |
|
| The loss of the chloride channel, ClC-5, delays apical iodide efflux and induces a euthyroid goiter in the mouse thyroid gland. | 2006-03 |
|
| Involvement of tumor necrosis factor-alpha in sulfur mustard-induced skin lesion; effect of topical iodine. | 2005-11 |
|
| Reverse transcriptase inhibitors down-regulate cell proliferation in vitro and in vivo and restore thyrotropin signaling and iodine uptake in human thyroid anaplastic carcinoma. | 2005-10 |
|
| [Effect of high-iodine intake on MBP mRNA expression in cerebrum of filial mice and selenium intervention]. | 2005-07 |
|
| Inhibition of N-methyl-N-nitrosourea-induced mammary carcinogenesis by molecular iodine (I2) but not by iodide (I-) treatment Evidence that I2 prevents cancer promotion. | 2005-05-31 |
|
| Thyrotropin-secreting pituitary adenoma responsive to bromocriptine therapy. | 2004-07-15 |
|
| Studies on experimental iodine allergy: 3. Low molecular weight elicitogenic antigens of iodine allergy. | 2004-05 |
|
| Thiocyanate induces cell necrosis and fibrosis in selenium- and iodine-deficient rat thyroids: a potential experimental model for myxedematous endemic cretinism in central Africa. | 2004-02 |
|
| Synergistic interaction between excess caffeine and deficient iodine on the promotion of thyroid carcinogenesis in rats pretreated with N-bis(2-hydroxypropyl)nitrosamine. | 2003-04 |
|
| Functional expression of sodium iodide symporter (NIS) in human breast cancer tissue. | 2003-01 |
|
| Effects of selenium and iodine on the expression of c-fos and c-jun mRNA and their proteins in cultured rat hippocampus neurons. | 2002-06 |
|
| Effects of selenium and iodine on c-fos and c-jun mRNA and their protein expressions in cultured rat hippocampus cells. | 2002 |
|
| Effects of iodine on inducible nitric oxide synthase and cyclooxygenase-2 expression in sulfur mustard-induced skin. | 2001-02 |
|
| Anti-goitrous effect of lecithin-bound iodine in propylthiouracil treated rats. | 2000-06 |
|
| Adverse reactions to nonionic iodine in contrast-enhanced computed tomography: usefulness of monitoring vital signs. | 1998-07 |
|
| Propylthiouracil-induced rapidly progressive glomerulonephritis associated with antineutrophil cytoplasmic autoantibodies. | 1997-07 |
|
| Case report: reversible mitral regurgitation and congestive heart failure complicating thyrotoxicosis. | 1996-03 |
|
| Thyroid adaptation to chronic tetraglycine hydroperiodide water purification tablet use. | 1995-01 |
|
| Subfulminant hepatitis requiring liver transplantation after benzarone administration. | 1994-06 |
|
| [Necrotizing hepatitis with a fatal outcome after carbimazole therapy]. | 1993-10-22 |
|
| The susceptibility of the fetus and child to chemical pollutants. Special susceptibility of the host to chemical agents: endocrinologic considerations. | 1974-05 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:08:37 GMT 2025
by
admin
on
Mon Mar 31 18:08:37 GMT 2025
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| Record UNII |
9Y91MC7XP8
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| Record Status |
Validated (UNII)
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| Record Version |
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DTXSID00211336
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76969054
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9Y91MC7XP8
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6227-40-3
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admin on Mon Mar 31 18:08:37 GMT 2025 , Edited by admin on Mon Mar 31 18:08:37 GMT 2025
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