U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula 4C2H5NO2.I2.2HI
Molecular Weight 809.9002
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GLYCINE HYDRIODIDE-IODINE

SMILES

I.I.II.NCC(O)=O.NCC(O)=O.NCC(O)=O.NCC(O)=O

InChI

InChIKey=GRSBODOCWBNPOF-UHFFFAOYSA-N
InChI=1S/4C2H5NO2.I2.2HI/c4*3-1-2(4)5;1-2;;/h4*1,3H2,(H,4,5);;2*1H

HIDE SMILES / InChI

Molecular Formula I2
Molecular Weight 253.8089
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula HI
Molecular Weight 127.9124
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C2H5NO2
Molecular Weight 75.0666
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Tetraglycine hydroperiodide is an iodine-containing chemical, used for water purification. Tetraglycine hydroperiodide is marketed in tablets; each tablet effectively disinfects 1 liter of clear water or 0.5 liter of tainted water by releasing approximately 8 mg free iodine. It requires approximately 30 minutes to inactivate target microorganisms and make water bacteriologically suitable for drinking. To remove iodine taste, a vitamin C pill is added to the kit.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Surgicide

Approved Use

Surgicide is a broad spectrum topical antiseptic for use on skin and mucous membranes. Use solution without dilution as needed
PubMed

PubMed

TitleDatePubMed
The susceptibility of the fetus and child to chemical pollutants. Special susceptibility of the host to chemical agents: endocrinologic considerations.
1974 May
[Necrotizing hepatitis with a fatal outcome after carbimazole therapy].
1993 Oct 22
Subfulminant hepatitis requiring liver transplantation after benzarone administration.
1994 Jun
Case report: reversible mitral regurgitation and congestive heart failure complicating thyrotoxicosis.
1996 Mar
Propylthiouracil-induced rapidly progressive glomerulonephritis associated with antineutrophil cytoplasmic autoantibodies.
1997 Jul
Adverse reactions to nonionic iodine in contrast-enhanced computed tomography: usefulness of monitoring vital signs.
1998 Jul
[Effect of high-iodine intake on MBP mRNA expression in cerebrum of filial mice and selenium intervention].
2005 Jul
Reverse transcriptase inhibitors down-regulate cell proliferation in vitro and in vivo and restore thyrotropin signaling and iodine uptake in human thyroid anaplastic carcinoma.
2005 Oct
Effect of selenium supplementation on activity and mRNA expression of type 1 deiodinase in mice with excessive iodine intake.
2006 Aug
Synergistic regulation of endothelial tight junctions by antioxidant (Se) and polyunsaturated lipid (GLA) via Claudin-5 modulation.
2006 Aug 1
Salt dual-fortified with iodine and micronized ground ferric pyrophosphate affects iron status but not hemoglobin in children in Cote d'Ivoire.
2006 Jul
Molecular iodine induces caspase-independent apoptosis in human breast carcinoma cells involving the mitochondria-mediated pathway.
2006 Jul 14
The loss of the chloride channel, ClC-5, delays apical iodide efflux and induces a euthyroid goiter in the mouse thyroid gland.
2006 Mar
Antiseptics, iodine, povidone iodine and traumatic wound cleansing.
2006 Nov
The treatment of Graves' disease in children.
2006 Sep
Sodium iodide symporter is expressed at the preneoplastic stages of liver carcinogenesis and in human cholangiocarcinoma.
2007 Apr
Goiter and other iodine deficiency disorders: A systematic review of epidemiological studies to deconstruct the complex web.
2007 Jan
Enhanced expression of adenovirus-mediated sodium iodide symporter gene in MCF-7 breast cancer cells with retinoic acid treatment.
2007 Mar
Comparison of the usefulness of gadodiamide and iodine mixture versus iodinated contrast alone for prevention of contrast-induced nephropathy in patients with chronic kidney disease undergoing coronary angiography.
2007 Oct 1
A blinded, randomized, palatability study comparing variations of 2 popular field water disinfection tablets.
2011 Dec
Patents

Patents

Substance Class Chemical
Created
by admin
on Fri Dec 15 15:47:16 GMT 2023
Edited
by admin
on Fri Dec 15 15:47:16 GMT 2023
Record UNII
9Y91MC7XP8
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
GLYCINE HYDRIODIDE-IODINE
Systematic Name English
GEOBALINE
Common Name English
BURSOLINE
Common Name English
GLYCINE, HYDRIODIDE, COMPD. WITH IODINE (4:2:1)
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID00211336
Created by admin on Fri Dec 15 15:47:16 GMT 2023 , Edited by admin on Fri Dec 15 15:47:16 GMT 2023
PRIMARY
PUBCHEM
76969054
Created by admin on Fri Dec 15 15:47:16 GMT 2023 , Edited by admin on Fri Dec 15 15:47:16 GMT 2023
PRIMARY
FDA UNII
9Y91MC7XP8
Created by admin on Fri Dec 15 15:47:16 GMT 2023 , Edited by admin on Fri Dec 15 15:47:16 GMT 2023
PRIMARY
CAS
6227-40-3
Created by admin on Fri Dec 15 15:47:16 GMT 2023 , Edited by admin on Fri Dec 15 15:47:16 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY