U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula I2
Molecular Weight 253.8089
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Iodine

SMILES

II

InChI

InChIKey=PNDPGZBMCMUPRI-UHFFFAOYSA-N
InChI=1S/I2/c1-2

HIDE SMILES / InChI

Molecular Formula I2
Molecular Weight 253.8089
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Tetraglycine hydroperiodide is an iodine-containing chemical, used for water purification. Tetraglycine hydroperiodide is marketed in tablets; each tablet effectively disinfects 1 liter of clear water or 0.5 liter of tainted water by releasing approximately 8 mg free iodine. It requires approximately 30 minutes to inactivate target microorganisms and make water bacteriologically suitable for drinking. To remove iodine taste, a vitamin C pill is added to the kit.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Surgicide

Approved Use

Surgicide is a broad spectrum topical antiseptic for use on skin and mucous membranes. Use solution without dilution as needed
PubMed

PubMed

TitleDatePubMed
[Necrotizing hepatitis with a fatal outcome after carbimazole therapy].
1993 Oct 22
Subfulminant hepatitis requiring liver transplantation after benzarone administration.
1994 Jun
Case report: reversible mitral regurgitation and congestive heart failure complicating thyrotoxicosis.
1996 Mar
Effects of iodine on inducible nitric oxide synthase and cyclooxygenase-2 expression in sulfur mustard-induced skin.
2001 Feb
Inhibition of N-methyl-N-nitrosourea-induced mammary carcinogenesis by molecular iodine (I2) but not by iodide (I-) treatment Evidence that I2 prevents cancer promotion.
2005 May 31
Involvement of tumor necrosis factor-alpha in sulfur mustard-induced skin lesion; effect of topical iodine.
2005 Nov
The loss of the chloride channel, ClC-5, delays apical iodide efflux and induces a euthyroid goiter in the mouse thyroid gland.
2006 Mar
Antiseptics, iodine, povidone iodine and traumatic wound cleansing.
2006 Nov
Increased iodine uptake in thyroid carcinoma after treatment with sodium butyrate and decitabine (5-Aza-dC).
2007 Nov
[The effects of iodine/selenium on the function of antigen presentation of peritoneal macrophages in rats].
2008 Jul
I-131 dose response for incident thyroid cancers in Ukraine related to the Chornobyl accident.
2011 Jul
Patents

Patents

Substance Class Chemical
Created
by admin
on Wed Jul 05 23:02:28 UTC 2023
Edited
by admin
on Wed Jul 05 23:02:28 UTC 2023
Record UNII
9679TC07X4
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Iodine
EP   HSDB   II   MART.   MI   USP   VANDF   WHO-DD   WHO-IP  
Systematic Name English
IODINE [USP MONOGRAPH]
Common Name English
IODINE [HSDB]
Common Name English
NSC-42355
Code English
IODIUM
HPUS  
Common Name English
IODIUM [HPUS]
Common Name English
IODINE STRONG [VANDF]
Common Name English
IODINE [EP IMPURITY]
Common Name English
IODINE [WHO-IP]
Common Name English
JODOSAN
Common Name English
IODINE [MI]
Common Name English
Iodine [WHO-DD]
Common Name English
IODINE [EP MONOGRAPH]
Common Name English
IODINE [II]
Common Name English
IODINE [VANDF]
Common Name English
IODINE [JAN]
Common Name English
TEGODYNE
Common Name English
IODINE MILD [VANDF]
Common Name English
IODINE [MART.]
Common Name English
IODINE STRONG
VANDF  
Common Name English
IODUM [WHO-IP LATIN]
Common Name English
Classification Tree Code System Code
LOINC 25448-2
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
LOINC 50868-9
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
LOINC 34321-0
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
WHO-VATC QD08AG03
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
LOINC 34320-2
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
LOINC 76657-6
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
LOINC 55928-6
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
LOINC 53872-8
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
LOINC 25936-6
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
LOINC 25449-0
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
NCI_THESAURUS C896
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
WHO-ATC D08AG03
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
WHO-VATC QD08AG53
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
EPA PESTICIDE CODE 46905
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
LOINC 2494-3
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
LOINC 44323-4
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
LOINC 26842-5
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
LOINC 2492-7
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
DSLD 184 (Number of products:5290)
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
DEA NO. 6699
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 27
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
LOINC 2495-0
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
Code System Code Type Description
CHEBI
17606
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY
MESH
D007455
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY
NCI_THESAURUS
C594
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY
HSDB
34
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY
CAS
7553-56-2
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY
WIKIPEDIA
Tincture of iodine
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY
ECHA (EC/EINECS)
231-442-4
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY
MERCK INDEX
M6327
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY Merck Index
DAILYMED
9679TC07X4
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY
WIKIPEDIA
Iodine (medical use)
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY
PUBCHEM
807
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY
FDA UNII
9679TC07X4
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY
EVMPD
SUB14239MIG
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY
DRUG BANK
DB05382
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
IODINE
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY Description: Heavy, greyish black plates or granules, having a metallic lustre. Solubility: Very slightly soluble in water; soluble in ethanol (~750 g/l) TS; freely soluble in carbon tetrachloride R, carbon disulfide R, and ether R. Category: External antiseptic. Storage: Iodine should be kept in a tightly closed container, preferably made of glass and provided with a glass stopper. Additional information: Iodine volatilizes slowly at room temperature giving violet, irritant vapours. Definition: Iodine contains not less than 99.5% and not more than 100.5% of I.
NSC
42355
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY
RXCUI
5933
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY RxNorm
DRUG CENTRAL
4446
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY
LACTMED
Iodine
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY
SMS_ID
100000092589
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY
EPA CompTox
DTXSID7034672
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY
CHEBI
24859
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY
ChEMBL
CHEMBL1201225
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY
WIKIPEDIA
Iodine
Created by admin on Wed Jul 05 23:02:28 UTC 2023 , Edited by admin on Wed Jul 05 23:02:28 UTC 2023
PRIMARY
Related Record Type Details
PARENT->REAGENT
LABELED -> NON-LABELED
PARENT->REAGENT
Related Record Type Details
ACTIVE MOIETY