Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C21H29NO |
| Molecular Weight | 311.4611 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2C(C)(C)C
InChI
InChIKey=OGNRRAFRDFGFKA-UHFFFAOYSA-N
InChI=1S/C21H29NO/c1-21(2,3)19-14-10-9-13-18(19)20(23-16-15-22(4)5)17-11-7-6-8-12-17/h6-14,20H,15-16H2,1-5H3
| Molecular Formula | C21H29NO |
| Molecular Weight | 311.4611 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Bufenadrine is a derivative of diphenhydramine. The compound was originally developed as an anti-motion sickness drug. Prolonged toxicity studies in rats, however, showed liver toxicity, and no further clinical evaluation was undertaken. Investigation of the metabolism showed that (-)-bufenadrine was enantiomer, exclusively responsible for toxic activities of the racemic compound.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Apr 02 09:46:30 GMT 2025
by
admin
on
Wed Apr 02 09:46:30 GMT 2025
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| Record UNII |
9Y0T619B3U
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| Record Status |
Validated (UNII)
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| Record Version |
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-
Download
| Name | Type | Language | ||
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Preferred Name | English | ||
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Official Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C29578
Created by
admin on Wed Apr 02 09:46:30 GMT 2025 , Edited by admin on Wed Apr 02 09:46:30 GMT 2025
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| Code System | Code | Type | Description | ||
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9Y0T619B3U
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604-74-0
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admin on Wed Apr 02 09:46:30 GMT 2025 , Edited by admin on Wed Apr 02 09:46:30 GMT 2025
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DTXSID70862278
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admin on Wed Apr 02 09:46:30 GMT 2025 , Edited by admin on Wed Apr 02 09:46:30 GMT 2025
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1385
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C73046
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CHEMBL2104614
Created by
admin on Wed Apr 02 09:46:30 GMT 2025 , Edited by admin on Wed Apr 02 09:46:30 GMT 2025
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21916
Created by
admin on Wed Apr 02 09:46:30 GMT 2025 , Edited by admin on Wed Apr 02 09:46:30 GMT 2025
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SUB05959MIG
Created by
admin on Wed Apr 02 09:46:30 GMT 2025 , Edited by admin on Wed Apr 02 09:46:30 GMT 2025
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100000088455
Created by
admin on Wed Apr 02 09:46:30 GMT 2025 , Edited by admin on Wed Apr 02 09:46:30 GMT 2025
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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|
ENANTIOMER -> RACEMATE | |||
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ENANTIOMER -> RACEMATE | |||
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SALT/SOLVATE -> PARENT |
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
