Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C13H9N5O6 |
| Molecular Weight | 331.2405 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)CN1C(=O)C(=O)NC2=C1C=C(N3C=CN=C3)C(=C2)[N+]([O-])=O
InChI
InChIKey=SPXYHZRWPRQLNS-UHFFFAOYSA-N
InChI=1S/C13H9N5O6/c19-11(20)5-17-8-4-9(16-2-1-14-6-16)10(18(23)24)3-7(8)15-12(21)13(17)22/h1-4,6H,5H2,(H,15,21)(H,19,20)
| Molecular Formula | C13H9N5O6 |
| Molecular Weight | 331.2405 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Zonampanel (also known as YM872) was developed as selective, potent and highly water-soluble competitive alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor antagonist. Zonampanel possesses the neuroprotective effect against focal cerebral ischemia and participated in phase II clinical trials in acute stroke patients. However, because of the severe effects, including hallucinations, agitation, and catatonia the further studied were terminated.
Originator
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:12:46 GMT 2025
by
admin
on
Mon Mar 31 19:12:46 GMT 2025
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| Record UNII |
9X33544ILS
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
Download
| Name | Type | Language | ||
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Common Name | English | ||
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Preferred Name | English | ||
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Common Name | English | ||
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Code | English | ||
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Code | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C47795
Created by
admin on Mon Mar 31 19:12:46 GMT 2025 , Edited by admin on Mon Mar 31 19:12:46 GMT 2025
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NCI_THESAURUS |
C1509
Created by
admin on Mon Mar 31 19:12:46 GMT 2025 , Edited by admin on Mon Mar 31 19:12:46 GMT 2025
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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300000034478
Created by
admin on Mon Mar 31 19:12:46 GMT 2025 , Edited by admin on Mon Mar 31 19:12:46 GMT 2025
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9X33544ILS
Created by
admin on Mon Mar 31 19:12:46 GMT 2025 , Edited by admin on Mon Mar 31 19:12:46 GMT 2025
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PRIMARY | |||
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C152964
Created by
admin on Mon Mar 31 19:12:46 GMT 2025 , Edited by admin on Mon Mar 31 19:12:46 GMT 2025
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PRIMARY | |||
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148200
Created by
admin on Mon Mar 31 19:12:46 GMT 2025 , Edited by admin on Mon Mar 31 19:12:46 GMT 2025
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PRIMARY | |||
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DTXSID50175232
Created by
admin on Mon Mar 31 19:12:46 GMT 2025 , Edited by admin on Mon Mar 31 19:12:46 GMT 2025
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PRIMARY | |||
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8154
Created by
admin on Mon Mar 31 19:12:46 GMT 2025 , Edited by admin on Mon Mar 31 19:12:46 GMT 2025
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PRIMARY | |||
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210245-80-0
Created by
admin on Mon Mar 31 19:12:46 GMT 2025 , Edited by admin on Mon Mar 31 19:12:46 GMT 2025
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PRIMARY | |||
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Zonampanel
Created by
admin on Mon Mar 31 19:12:46 GMT 2025 , Edited by admin on Mon Mar 31 19:12:46 GMT 2025
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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TARGET -> INHIBITOR |
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|
SOLVATE->ANHYDROUS | |||
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SALT/SOLVATE -> PARENT |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
