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Details

Stereochemistry ABSOLUTE
Molecular Formula C27H44N4O5
Molecular Weight 504.6621
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIHEXA

SMILES

CCCCCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCCCCCC(N)=O

InChI

InChIKey=XEUVNVNAVKZSPT-JTJYXVOQSA-N
InChI=1S/C27H44N4O5/c1-4-6-8-12-24(34)30-22(18-20-13-15-21(32)16-14-20)26(35)31-25(19(3)5-2)27(36)29-17-10-7-9-11-23(28)33/h13-16,19,22,25,32H,4-12,17-18H2,1-3H3,(H2,28,33)(H,29,36)(H,30,34)(H,31,35)/t19-,22-,25-/m0/s1

HIDE SMILES / InChI

Molecular Formula C27H44N4O5
Molecular Weight 504.6621
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 3 / 3
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Substance Class Chemical
Created
by admin
on Sat Dec 16 01:30:19 GMT 2023
Edited
by admin
on Sat Dec 16 01:30:19 GMT 2023
Record UNII
9WYX65A5C2
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DIHEXA
Common Name English
L-ISOLEUCINAMIDE, N-(1-OXOHEXYL)-L-TYROSYL-N-(6-AMINO-6-OXOHEXYL)-
Systematic Name English
ATH-1001
Code English
6-(2-(2-HEXANAMIDO-3-(4-HYDROXYPHENYL)PROPANAMIDO)-3-METHYLPENTANAMIDO)HEXANAMIDE
Systematic Name English
PNB-0408
Code English
N-(1-OXOHEXYL)-L-TYROSYL-N-(6-AMINO-6-OXOHEXYL)-L-ISOLEUCINAMIDE
Systematic Name English
N-HEXANOIC-TYR-ILE-(6) AMINOHEXANOIC AMIDE
Common Name English
Code System Code Type Description
PUBCHEM
129010512
Created by admin on Sat Dec 16 01:30:19 GMT 2023 , Edited by admin on Sat Dec 16 01:30:19 GMT 2023
PRIMARY
CAS
1401708-83-5
Created by admin on Sat Dec 16 01:30:19 GMT 2023 , Edited by admin on Sat Dec 16 01:30:19 GMT 2023
PRIMARY
WIKIPEDIA
DIHEXA
Created by admin on Sat Dec 16 01:30:19 GMT 2023 , Edited by admin on Sat Dec 16 01:30:19 GMT 2023
PRIMARY Dihexa, also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, is an oligopeptide and angiotensin IV-derived drug that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met. Dihexa dramatically improves cognitive function in animal models of Alzheimer's disease-like mental impairment. In an assay of neurotrophic activity, Dihexa was found to be seven orders of magnitude more potent than brain-derived neurotrophic factor.
MANUFACTURER PRODUCT INFORMATION
DIHEXA
Created by admin on Sat Dec 16 01:30:19 GMT 2023 , Edited by admin on Sat Dec 16 01:30:19 GMT 2023
PRIMARY The pharmacology of Dihexa in animals is well-documented: in vitro, the synaptogenesis of Dihexa begins at T+30:00, maximizes at +48:00:00. The overall half-life of the drug is currently charted at approximately a week: longer than just about any other neurogenic compound.Read more: http://www.nootropix.com/dihexa-story-and-science-of-a-neurogenic-wonder-drug/#ixzz454OKqZ00
EPA CompTox
DTXSID701032895
Created by admin on Sat Dec 16 01:30:19 GMT 2023 , Edited by admin on Sat Dec 16 01:30:19 GMT 2023
PRIMARY
FDA UNII
9WYX65A5C2
Created by admin on Sat Dec 16 01:30:19 GMT 2023 , Edited by admin on Sat Dec 16 01:30:19 GMT 2023
PRIMARY
Related Record Type Details
TARGET -> ACTIVATOR
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PRODRUG -> METABOLITE ACTIVE
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ACTIVE MOIETY