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Details

Stereochemistry ACHIRAL
Molecular Formula 2C2H3O2.Mn.4H2O
Molecular Weight 245.0872
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MANGANESE ACETATE TETRAHYDRATE

SMILES

O.O.O.O.[Mn++].CC([O-])=O.CC([O-])=O

InChI

InChIKey=CESXSDZNZGSWSP-UHFFFAOYSA-L
InChI=1S/2C2H4O2.Mn.4H2O/c2*1-2(3)4;;;;;/h2*1H3,(H,3,4);;4*1H2/q;;+2;;;;/p-2

HIDE SMILES / InChI

Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C2H4O2
Molecular Weight 60.052
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Mn
Molecular Weight 54.938
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Manganese citrate is generally recognized as safe direct food additive. Manganese citrate complex has being used in the determination of liver enzyme activities in the aging process and following treatment with aminoethylisothiuronium bromide hydrobromide (AET).

Approval Year

Targets

Targets

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
Primary
Unknown

Approved Use

Manganese is used for prevention and treatment of manganese deficiency, a condition in which the body doesn’t have enough manganese.
Primary
Unknown

Approved Use

Manganese is used for weak bones (osteoporosis).
Palliative
Unknown

Approved Use

Early research suggests that taking manganese along with calcium helps improve symptoms of PMS, including pain, crying, loneliness, anxiety, restlessness, irritability, mood swings, depression, and tension.
Curative
MANGANESE SULFATE

Approved Use

Manganese Sulfate Injection, USP is indicated for use as a supplement to intravenous solutions given for Total Parenteral Nutrition (TPN). Administration helps to maintain plasma levels and to prevent depletion of endogenous stores and subsequent deficiency symptoms.
Primary
MANGANESE SULFATE

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Cytochrome oxidase determination using a manganese citrate complex.
1970
Effect of fluoride on copper, manganese and zinc in bone and kidney.
1981 Mar
Manganese citrate improves base-calling accuracy in DNA sequencing reactions using rhodamine-based fluorescent dye-terminators.
1999 Mar 1
Manganese citrate chemistry: syntheses, spectroscopic studies, and structural characterizations of novel mononuclear, water-soluble manganese citrate complexes.
2000 Sep 4
Tetraaqua(1,10-phenanthroline-kappa(2)N,N')manganese(II) sulfate dihydrate.
2002 Jul
Is the axial zero-field splitting parameter of tetragonally elongated high-spin manganese(III) complexes always negative?
2002 Jul 31
Effects of chronic manganese exposure on glutamatergic and GABAergic neurotransmitter markers in the nonhuman primate brain.
2009 Sep
Safety Assessment of Citric Acid, Inorganic Citrate Salts, and Alkyl Citrate Esters as Used in Cosmetics.
2014 May
Chronic exposure to manganese sulfate leads to adverse dose-dependent effects on the neurobehavioral ability of rats.
2016 Nov
Top-Down Strategy to Synthesize Mesoporous Dual Carbon Armored MnO Nanoparticles for Lithium-Ion Battery Anodes.
2017 Apr 12
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Curator's Comment: In vitro cytotoxicity of manganese oxide (MnO) using live/dead cell assay, lactate dehydrogenase assay, and reactive oxygen species detection with variation of the concentration of nanoparticles (5-500 ug/ml), incubation time (18-96 h), and different human cell lines (lung adenocarcinoma, breast cancer cells, and glioblastoma cells) was studied. The cytotoxic effect was negligible for 18 h incubation even at highest concentration of 500 ug/ml MnO nanoparticle.
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:05:48 UTC 2023
Edited
by admin
on Fri Dec 15 16:05:48 UTC 2023
Record UNII
9TO51D176N
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MANGANESE ACETATE TETRAHYDRATE
Systematic Name English
MANGANESE(II) ACETATE TETRAHYDRATE
Systematic Name English
MANGANUM ACETICUM [HPUS]
Common Name English
ACETIC ACID, MANGANESE(2+) SALT, TETRAHYDRATE
Common Name English
MANGANESE DIACETATE TETRAHYDRATE
Systematic Name English
MANGANESE DIACETATE, TETRAHYDRATE
Systematic Name English
MANGANOUS ACETATE TETRAHYDRATE
Common Name English
MANGANUM ACETICUM
HPUS  
Common Name English
Code System Code Type Description
CAS
6156-78-1
Created by admin on Fri Dec 15 16:05:48 UTC 2023 , Edited by admin on Fri Dec 15 16:05:48 UTC 2023
PRIMARY
SMS_ID
300000040890
Created by admin on Fri Dec 15 16:05:48 UTC 2023 , Edited by admin on Fri Dec 15 16:05:48 UTC 2023
PRIMARY
RXCUI
1366224
Created by admin on Fri Dec 15 16:05:48 UTC 2023 , Edited by admin on Fri Dec 15 16:05:48 UTC 2023
PRIMARY RxNorm
PUBCHEM
93021
Created by admin on Fri Dec 15 16:05:48 UTC 2023 , Edited by admin on Fri Dec 15 16:05:48 UTC 2023
PRIMARY
DAILYMED
9TO51D176N
Created by admin on Fri Dec 15 16:05:48 UTC 2023 , Edited by admin on Fri Dec 15 16:05:48 UTC 2023
PRIMARY
FDA UNII
9TO51D176N
Created by admin on Fri Dec 15 16:05:48 UTC 2023 , Edited by admin on Fri Dec 15 16:05:48 UTC 2023
PRIMARY
EPA CompTox
DTXSID00210566
Created by admin on Fri Dec 15 16:05:48 UTC 2023 , Edited by admin on Fri Dec 15 16:05:48 UTC 2023
PRIMARY
Related Record Type Details
ANHYDROUS->SOLVATE
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY