Azenosertib

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C29H34N8O2
Molecular Weight	526.6327
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC[C@@]1(O)CCC2=CC=C(N=C12)N3N(CC=C)C(=O)C4=CN=C(NC5=CC=C(C=C5)N6CCN(C)CC6)N=C34

InChI

InChIKey=OXTSYWDBUVRXFF-GDLZYMKVSA-N

InChI=1S/C29H34N8O2/c1-4-14-36-27(38)23-19-30-28(31-21-7-9-22(10-8-21)35-17-15-34(3)16-18-35)33-26(23)37(36)24-11-6-20-12-13-29(39,5-2)25(20)32-24/h4,6-11,19,39H,1,5,12-18H2,2-3H3,(H,30,31,33)/t29-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C29H34N8O2
Molecular Weight	526.6327
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 15:18:15 GMT 2023` Edited by `admin` on `Sat Dec 16 15:18:15 GMT 2023`
Record UNII	9J13XU96Z1
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Azenosertib

Official Name

English

1-[(7R)-7-éthyl-7-hydroxy-6,7-dihydro-5Hcyclopenta[b]pyridin-2-yl]-6-[4-(4-méthylpipérazin-1-yl)anilino]-2-(prop-2-én-1-yl)-1,2-dihydro-3Hpyrazolo[3,4-d]pyrimidin-3-one

Systematic Name

English

3H-PYRAZOLO(3,4-D)PYRIMIDIN-3-ONE, 1-((7R)-7-ETHYL-6,7-DIHYDRO-7-HYDROXY-5H-CYCLOPENTA(B)PYRIDIN-2-YL)-1,2-DIHYDRO-6-((4-(4-METHYL-1-PIPERAZINYL)PHENYL)AMINO)-2-(2-PROPEN-1-YL)-

Systematic Name

English

Azenosertib [INN]

Common Name

English

(R)-2-allyl-1-(7-ethyl-7-hydroxy-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)-6-((4-(4-methylpiperazin-1-yl)phenyl)amino)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one

Systematic Name

English

ZN-c3 [WHO-DD]

Common Name

English

ZN-C3

Code

English

1-[(7R)-7-ethyl-7-hydroxy-6,7-dihydro-5Hcyclopenta[ b]pyridin-2-yl]-6-[4-(4-methylpiperazin-1- yl)anilino]-2-(prop-2-en-1-yl)-1,2-dihydro-3Hpyrazolo[ 3,4-d]pyrimidin-3-one

Systematic Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

772420