WEE1-LIKE PROTEIN KINASE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 19:46:14 GMT 2025` Edited by `admin` on `Tue Apr 01 19:46:14 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	V6HYU3TM3V
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

KINASE (PHOSPHORYLATING), PROTEIN (TYROSINE) (HUMAN CLONE 1E-12 GENE WEE1HU)

Preferred Name

English

WEE1-LIKE PROTEIN KINASE

Common Name

English

WEE1HU CDK TYROSINE 15-KINASE (HUMAN HELA CELL CLONE 1E-12)

Common Name

English

WEE1A KINASE

Common Name

English

WEE1

Common Name

English

Code System Code Type Description

PHAROS

P30291

Created by admin on Tue Apr 01 19:46:14 GMT 2025 , Edited by admin on Tue Apr 01 19:46:14 GMT 2025

PRIMARY

CAS

391965-95-0

Created by admin on Tue Apr 01 19:46:14 GMT 2025 , Edited by admin on Tue Apr 01 19:46:14 GMT 2025

PRIMARY

WIKIPEDIA

WEE1

Created by admin on Tue Apr 01 19:46:14 GMT 2025 , Edited by admin on Tue Apr 01 19:46:14 GMT 2025

PRIMARY

CAS

167976-02-5

Created by admin on Tue Apr 01 19:46:14 GMT 2025 , Edited by admin on Tue Apr 01 19:46:14 GMT 2025

ALTERNATIVE

FDA UNII

V6HYU3TM3V

Created by admin on Tue Apr 01 19:46:14 GMT 2025 , Edited by admin on Tue Apr 01 19:46:14 GMT 2025

PRIMARY

EC (ENZYME CLASS)

EC 2.7.10.2

Created by admin on Tue Apr 01 19:46:14 GMT 2025 , Edited by admin on Tue Apr 01 19:46:14 GMT 2025

PRIMARY

UNIPROT

P30291

Created by admin on Tue Apr 01 19:46:14 GMT 2025 , Edited by admin on Tue Apr 01 19:46:14 GMT 2025

PRIMARY

Related Record Type Details


					9J13XU96Z1

INHIBITOR -> TARGET

Amount:


					621K13UG4B

INHIBITOR -> TARGET

Amount:


					5018V4AEZ0

BOSUTINIB

INHIBITOR -> TARGET


					F2UH9R2JT6

6-(2,6-Dichlorophenyl)-2-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one

INHIBITOR -> TARGET


					HRE3327KCX

SC-0191

INHIBITOR -> TARGET

Interaction Type:

PRECLINICAL

Qualification:

IC50


					S6U3J3UP11

SB-218078

INHIBITOR -> TARGET

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_642]		SERINE		DEXFOSFOSERINE	VI4F0K069V
AMINO ACID SUBSTITUTION	[1_123]		SERINE		DEXFOSFOSERINE	VI4F0K069V
AMINO ACID SUBSTITUTION	[1_53]		SERINE		DEXFOSFOSERINE	VI4F0K069V

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER AVERAGE(CALCULATED)	CHEMICAL