Details
Stereochemistry | ACHIRAL |
Molecular Formula | C4H10O2S |
Molecular Weight | 122.186 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
OCCSCCO
InChI
InChIKey=YODZTKMDCQEPHD-UHFFFAOYSA-N
InChI=1S/C4H10O2S/c5-1-3-7-4-2-6/h5-6H,1-4H2
Molecular Formula | C4H10O2S |
Molecular Weight | 122.186 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Thiodiglycol is the organosulfur structurally similar to diethylene glycol used as a solvent in a variety of applications ranging from dyeing textiles to inks in some ballpoint pens. In chemical synthesis, it is used as a building block for protection products, dispersants, fibers, plasticizers, rubber accelerators, pesticides, dyes, and various other organic chemicals. In the manufacture of polymers, it is used as a chain transfer agent. Thiodiglycol is a precursor in the production of Sulfur mustard and it is also considered as a “Schedule 2” compound (dual-use chemicals with low to moderate commercial use and high-risk precursors) within the terms of the Chemical Weapons Convention treaty.
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Genetic modification of glaucoma associated phenotypes between AKXD-28/Ty and DBA/2J mice. | 2001 |
|
Overalkylation of a protein digest with iodoacetamide. | 2001 Aug 1 |
|
Analysis of the degradation compounds of chemical warfare agents using liquid chromatography/mass spectrometry. | 2001 Dec |
|
Reactions of VX, GB, GD, and HD with nanosize Al(2)O(3). Formation of aluminophosphonates. | 2001 Feb 28 |
|
Extraction of thiodiglycol from soil using pressurised liquid extraction. | 2001 Jan 12 |
|
Capillary gas chromatography-atomic emission spectroscopy-mass spectrometry analysis of sulphur mustard and transformation products in a block recovered from the Baltic Sea. | 2001 Jun 1 |
|
Determination of thiodyglycol in groundwater using solid-phase extraction followed by gas chromatography with mass spectrometric detection in the selected-ion mode. | 2001 Mar 9 |
|
Percutaneous absorption of explosives and related compounds: an empirical model of bioavailability of organic nitro compounds from soil. | 2002 Jul 15 |
|
[The bioutilization of thiodiglycol (a breakdown product of mustard gas): isolation of degraders and investigation of degradation conditions]. | 2002 Mar-Apr |
|
Transformation of thiodiglycol by resting cells of Alcaligenes xylosoxydans PGH10. | 2002 Mar-Apr |
|
[Thiodiglycol metabolism in Alcaligenes xylosoxydans subsp. denitrificans]. | 2002 Sep-Oct |
|
Ring-opening reactions induced by gold(I) of five- and four-coordinate palladium(II) and platinum(II) complexes containing tripodal or linear polyphosphines. | 2004 Aug 21 |
|
Determination of thiodiglycol, a mustard gas hydrolysis product by gas chromatography-mass spectrometry after tert-butyldimethylsilylation. | 2004 Dec 24 |
|
Reactions of sulphur mustard on impregnated carbons. | 2004 Dec 31 |
|
Oxoammonium salts. 9. Oxidative dimerization of polyfunctional primary alcohols to esters. An interesting beta oxygen effect. | 2004 Jul 23 |
|
Quantitation of the sulfur mustard metabolites 1,1'-sulfonylbis[2-(methylthio)ethane] and thiodiglycol in urine using isotope-dilution Gas chromatography-tandem mass spectrometry. | 2004 Jul-Aug |
|
Monitoring sulfur mustard exposure by gas chromatography-mass spectrometry analysis of thiodiglycol cleaved from blood proteins. | 2004 Jul-Aug |
|
Packed capillary liquid chromatography-electrospray ionization (tandem) mass spectrometry of mustard hydrolysis products in soil. | 2004 Nov 26 |
|
Quantitative analysis of the sulfur mustard hydrolysis product thiodiglycol (2,2'-sulfobisethanol) in in vivo microdialysates using gas chromatography coupled with pulsed flame photometric detection. | 2005 Jul |
|
Kinetics of degradation of sulphur mustard on impregnated carbons. | 2005 May 20 |
|
Toxicity assessment of thiodiglycol. | 2005 Nov-Dec |
|
Mercury transformations in chemical agent simulant as characterized by X-ray absorption fine spectroscopy. | 2005 Oct 15 |
|
NMR analysis of thiodiglycol oxidation by Mammalian alcohol dehydrogenases. | 2006 |
|
2,2'-thiodiethanol: a new water soluble mounting medium for high resolution optical microscopy. | 2007 Jan |
|
Differential affinity of mammalian histone H1 somatic subtypes for DNA and chromatin. | 2007 May 11 |
|
Chronic health effects of sulphur mustard exposure with special reference to Iranian veterans. | 2008 |
|
The effect of mustard gas on the biological activity of soil. | 2008 Mar |
|
Water-induced hydrophobicity of soy protein materials containing 2,2-diphenyl-2-hydroxyethanoic acid. | 2008 Sep |
|
Screening hydrolysis products of sulfur mustard agents by high-performance liquid chromatography with inductively coupled plasma mass spectrometry detection. | 2009 Apr |
|
Optimization of codon composition and regulatory elements for expression of human insulin like growth factor-1 in transgenic chloroplasts and evaluation of structural identity and function. | 2009 Apr 3 |
|
Microbial responses to mustard gas dumped in the Baltic Sea. | 2009 Aug |
|
Modified titania nanotubes for decontamination of sulphur mustard. | 2009 Aug 15 |
|
Reactions of sulphur mustard and sarin on V 1.02 O 2.98 nanotubes. | 2009 Jul 30 |
|
Comparison of metal-dependent catalysis by HIV-1 and ASV integrase proteins using a new and rapid, moderate throughput assay for joining activity in solution. | 2009 Jun 29 |
|
Capsaicinoids, chloropicrin and sulfur mustard: possibilities for exposure biomarkers. | 2010 |
|
Amino acid availability controls TRB3 transcription in liver through the GCN2/eIF2α/ATF4 pathway. | 2010 Dec 21 |
|
Dithiothreitol causes HIV-1 integrase dimer dissociation while agents interacting with the integrase dimer interface promote dimer formation. | 2011 Mar 15 |
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/16393936
NOAEL (rat) 500 mg/kg/day for 90 days
Route of Administration:
Oral
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:47:22 GMT 2023
by
admin
on
Fri Dec 15 15:47:22 GMT 2023
|
Record UNII |
9BW5T43J04
|
Record Status |
Validated (UNII)
|
Record Version |
|
-
Download
Name | Type | Language | ||
---|---|---|---|---|
|
Official Name | English | ||
|
Code | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
Classification Tree | Code System | Code | ||
---|---|---|---|---|
|
NCI_THESAURUS |
C1590
Created by
admin on Fri Dec 15 15:47:22 GMT 2023 , Edited by admin on Fri Dec 15 15:47:22 GMT 2023
|
Code System | Code | Type | Description | ||
---|---|---|---|---|---|
|
C75295
Created by
admin on Fri Dec 15 15:47:22 GMT 2023 , Edited by admin on Fri Dec 15 15:47:22 GMT 2023
|
PRIMARY | |||
|
CHEMBL444480
Created by
admin on Fri Dec 15 15:47:22 GMT 2023 , Edited by admin on Fri Dec 15 15:47:22 GMT 2023
|
PRIMARY | |||
|
m10753
Created by
admin on Fri Dec 15 15:47:22 GMT 2023 , Edited by admin on Fri Dec 15 15:47:22 GMT 2023
|
PRIMARY | Merck Index | ||
|
7482
Created by
admin on Fri Dec 15 15:47:22 GMT 2023 , Edited by admin on Fri Dec 15 15:47:22 GMT 2023
|
PRIMARY | |||
|
DTXSID6026878
Created by
admin on Fri Dec 15 15:47:22 GMT 2023 , Edited by admin on Fri Dec 15 15:47:22 GMT 2023
|
PRIMARY | |||
|
199
Created by
admin on Fri Dec 15 15:47:22 GMT 2023 , Edited by admin on Fri Dec 15 15:47:22 GMT 2023
|
PRIMARY | |||
|
SUB10977MIG
Created by
admin on Fri Dec 15 15:47:22 GMT 2023 , Edited by admin on Fri Dec 15 15:47:22 GMT 2023
|
PRIMARY | |||
|
C047519
Created by
admin on Fri Dec 15 15:47:22 GMT 2023 , Edited by admin on Fri Dec 15 15:47:22 GMT 2023
|
PRIMARY | |||
|
6289
Created by
admin on Fri Dec 15 15:47:22 GMT 2023 , Edited by admin on Fri Dec 15 15:47:22 GMT 2023
|
PRIMARY | |||
|
9BW5T43J04
Created by
admin on Fri Dec 15 15:47:22 GMT 2023 , Edited by admin on Fri Dec 15 15:47:22 GMT 2023
|
PRIMARY | |||
|
111-48-8
Created by
admin on Fri Dec 15 15:47:22 GMT 2023 , Edited by admin on Fri Dec 15 15:47:22 GMT 2023
|
PRIMARY | |||
|
75184
Created by
admin on Fri Dec 15 15:47:22 GMT 2023 , Edited by admin on Fri Dec 15 15:47:22 GMT 2023
|
PRIMARY | |||
|
THIODIGLYCOL
Created by
admin on Fri Dec 15 15:47:22 GMT 2023 , Edited by admin on Fri Dec 15 15:47:22 GMT 2023
|
PRIMARY | |||
|
100000082420
Created by
admin on Fri Dec 15 15:47:22 GMT 2023 , Edited by admin on Fri Dec 15 15:47:22 GMT 2023
|
PRIMARY | |||
|
203-874-3
Created by
admin on Fri Dec 15 15:47:22 GMT 2023 , Edited by admin on Fri Dec 15 15:47:22 GMT 2023
|
PRIMARY | |||
|
5447
Created by
admin on Fri Dec 15 15:47:22 GMT 2023 , Edited by admin on Fri Dec 15 15:47:22 GMT 2023
|
PRIMARY |
Related Record | Type | Details | ||
---|---|---|---|---|
|
ACTIVE MOIETY |