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Details

Stereochemistry ACHIRAL
Molecular Formula C22H22O6
Molecular Weight 382.4065
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GLYCYRIN

SMILES

COC1=C(CC=C(C)C)C(OC)=C2C=C(C(=O)OC2=C1)C3=C(O)C=C(O)C=C3

InChI

InChIKey=FWWGXZYUURXJLK-UHFFFAOYSA-N
InChI=1S/C22H22O6/c1-12(2)5-7-15-19(26-3)11-20-17(21(15)27-4)10-16(22(25)28-20)14-8-6-13(23)9-18(14)24/h5-6,8-11,23-24H,7H2,1-4H3

HIDE SMILES / InChI

Molecular Formula C22H22O6
Molecular Weight 382.4065
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Anti-hepatitis C virus compounds obtained from Glycyrrhiza uralensis and other Glycyrrhiza species.
2014-03
Effect of Carnitine and herbal mixture extract on obesity induced by high fat diet in rats.
2009-10-16
Activated PPARgamma Targets Surface and Intracellular Signals That Inhibit the Proliferation of Lung Carcinoma Cells.
2008
Peroxisome proliferator-activated receptors in lung cancer.
2007
Phenolics with PPAR-gamma ligand-binding activity obtained from licorice (Glycyrrhiza uralensis roots) and ameliorative effects of glycyrin on genetically diabetic KK-A(y) mice.
2003-12-15
Anti-Helicobacter pylori flavonoids from licorice extract.
2002-08-09
Antibacterial compounds of licorice against upper airway respiratory tract pathogens.
2001-06
Cytotoxic activity of low molecular weight polyphenols against human oral tumor cell lines.
2000-08-23
Patents

Patents

Substance Class Chemical
Created
by admin
on Mon Mar 31 22:37:37 GMT 2025
Edited
by admin
on Mon Mar 31 22:37:37 GMT 2025
Record UNII
994BQ9M3AV
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
GLYCYRIN
Common Name English
2H-1-BENZOPYRAN-2-ONE, 3-(2,4-DIHYDROXYPHENYL)-5,7-DIMETHOXY-6-(3-METHYL-2-BUTEN-1-YL)-
Preferred Name English
Code System Code Type Description
CAS
66056-18-6
Created by admin on Mon Mar 31 22:37:37 GMT 2025 , Edited by admin on Mon Mar 31 22:37:37 GMT 2025
PRIMARY
PUBCHEM
480787
Created by admin on Mon Mar 31 22:37:37 GMT 2025 , Edited by admin on Mon Mar 31 22:37:37 GMT 2025
PRIMARY
EPA CompTox
DTXSID50216255
Created by admin on Mon Mar 31 22:37:37 GMT 2025 , Edited by admin on Mon Mar 31 22:37:37 GMT 2025
PRIMARY
FDA UNII
994BQ9M3AV
Created by admin on Mon Mar 31 22:37:37 GMT 2025 , Edited by admin on Mon Mar 31 22:37:37 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> CONSTITUENT ALWAYS PRESENT
Glycyrin was tested for antimicrobial activity against methicillin sensitive Staphylococcus aureus, methicillin resistant S. aureus, Micrococcus luteus, Bacillus subtilis, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa and found to be inactive.
PARENT -> CONSTITUENT ALWAYS PRESENT
Coumarin
PARENT -> CONSTITUENT ALWAYS PRESENT
Anti-HCV activity was found to be 7.2ug/mL.
PARENT -> CONSTITUENT ALWAYS PRESENT