U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C22H22O6
Molecular Weight 382.4065
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GLYCYRIN

SMILES

COC1=C(CC=C(C)C)C(OC)=C2C=C(C(=O)OC2=C1)C3=CC=C(O)C=C3O

InChI

InChIKey=FWWGXZYUURXJLK-UHFFFAOYSA-N
InChI=1S/C22H22O6/c1-12(2)5-7-15-19(26-3)11-20-17(21(15)27-4)10-16(22(25)28-20)14-8-6-13(23)9-18(14)24/h5-6,8-11,23-24H,7H2,1-4H3

HIDE SMILES / InChI

Molecular Formula C22H22O6
Molecular Weight 382.4065
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Antibacterial compounds of licorice against upper airway respiratory tract pathogens.
2001 Jun
Activated PPARgamma Targets Surface and Intracellular Signals That Inhibit the Proliferation of Lung Carcinoma Cells.
2008
Anti-hepatitis C virus compounds obtained from Glycyrrhiza uralensis and other Glycyrrhiza species.
2014 Mar
Patents

Patents

Substance Class Chemical
Created
by admin
on Sat Dec 16 09:22:05 UTC 2023
Edited
by admin
on Sat Dec 16 09:22:05 UTC 2023
Record UNII
994BQ9M3AV
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
GLYCYRIN
Common Name English
2H-1-BENZOPYRAN-2-ONE, 3-(2,4-DIHYDROXYPHENYL)-5,7-DIMETHOXY-6-(3-METHYL-2-BUTEN-1-YL)-
Systematic Name English
Code System Code Type Description
CAS
66056-18-6
Created by admin on Sat Dec 16 09:22:05 UTC 2023 , Edited by admin on Sat Dec 16 09:22:05 UTC 2023
PRIMARY
PUBCHEM
480787
Created by admin on Sat Dec 16 09:22:05 UTC 2023 , Edited by admin on Sat Dec 16 09:22:05 UTC 2023
PRIMARY
EPA CompTox
DTXSID50216255
Created by admin on Sat Dec 16 09:22:05 UTC 2023 , Edited by admin on Sat Dec 16 09:22:05 UTC 2023
PRIMARY
FDA UNII
994BQ9M3AV
Created by admin on Sat Dec 16 09:22:05 UTC 2023 , Edited by admin on Sat Dec 16 09:22:05 UTC 2023
PRIMARY
Related Record Type Details
PARENT -> CONSTITUENT ALWAYS PRESENT
Glycyrin was tested for antimicrobial activity against methicillin sensitive Staphylococcus aureus, methicillin resistant S. aureus, Micrococcus luteus, Bacillus subtilis, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa and found to be inactive.
PARENT -> CONSTITUENT ALWAYS PRESENT
Coumarin
PARENT -> CONSTITUENT ALWAYS PRESENT
Anti-HCV activity was found to be 7.2ug/mL.
PARENT -> CONSTITUENT ALWAYS PRESENT