GLYCYRRHIZA URALENSIS ROOT

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Sat Dec 16 10:25:02 UTC 2023` Edited by `admin` on `Sat Dec 16 10:25:02 UTC 2023`
Source Materials Class	ORGANISM
Source Materials Type	PLANT
Source Materials Parent	`8XW1DS8UIR` GLYCYRRHIZA URALENSIS WHOLE
Part	RHIZOME; ROOT; STOLON
Record UNII	42B5YD8F0K
Record Status	`Validated (UNII)`
Record Version

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Related Record	Type

Name

Type

Language

GLYCYRRHIZA URALENSIS

Preferred Name

English

GLYCYRRHIZA URALENSIS ROOT

Common Name

English

GANCAO (GLYCYRRHIZA URALENSIS)

Common Name

English

LOLOZ WITH CAVIBLOC

Brand Name

English

Glycyrrhiza uralensis root [WHO-DD]

Common Name

English

LIQUORICE ROOT (GLYCYRRHIZA URALENSIS)

Common Name

English

GLYCYRRHIZAE RADIX ET RHIZOMA (GLYCYRRHIZA URALENSIS)

Common Name

English

PHY-906 COMPONENT GLYCYRRHIZA URALENSIS ROOT

Common Name

English

URAL LICORICE ROOT

Common Name

English

GLYCYRRHIZAE RADIX ET RHIZOMA (GLYCYRRHIZA URALENSIS) [CHP]

Common Name

English

WU LA GAN CAO ROOT

Common Name

English

GLYCYRRHIZA URALENSIS ROOT WITH RHIZOME

Common Name

English

Glycyrrhiza uralensis root with rhizome [WHO-DD]

Common Name

English

CHINESE HERBAL FORMULATION PHY906 COMPONENT GLYCYRRHIZA URALENSIS ROOT

Common Name

English

GLYCYRRHIZA (GLYCYRRHIZA URALENSIS) [JP]

Common Name

English

YIV-906 COMPONENT GLYCYRRHIZA URALENSIS ROOT

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C79664

Created by admin on Sat Dec 16 10:25:09 UTC 2023 , Edited by admin on Sat Dec 16 10:25:09 UTC 2023

DSLD

3014 (Number of products:192)

Created by admin on Sat Dec 16 10:25:09 UTC 2023 , Edited by admin on Sat Dec 16 10:25:09 UTC 2023

Code System Code Type Description

NCI_THESAURUS

C80296

Created by admin on Sat Dec 16 10:25:09 UTC 2023 , Edited by admin on Sat Dec 16 10:25:09 UTC 2023

PRIMARY

EVMPD

SUB130189

Created by admin on Sat Dec 16 10:25:09 UTC 2023 , Edited by admin on Sat Dec 16 10:25:09 UTC 2023

PRIMARY

RXCUI

1342493

Created by admin on Sat Dec 16 10:25:09 UTC 2023 , Edited by admin on Sat Dec 16 10:25:09 UTC 2023

PRIMARY

RxNorm

FDA UNII

42B5YD8F0K

Created by admin on Sat Dec 16 10:25:09 UTC 2023 , Edited by admin on Sat Dec 16 10:25:09 UTC 2023

PRIMARY

DAILYMED

42B5YD8F0K

Created by admin on Sat Dec 16 10:25:09 UTC 2023 , Edited by admin on Sat Dec 16 10:25:09 UTC 2023

PRIMARY

EVMPD

SUB33295

Created by admin on Sat Dec 16 10:25:09 UTC 2023 , Edited by admin on Sat Dec 16 10:25:09 UTC 2023

PRIMARY

Related Record Type Details


					355E7H7EHH

ISOLICOFLAVONOL

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

ISOLICOFLAVONOL showed antibacterial activity against MSSAs (strains FDA 209P and Smith) and MRSAs(strains K3 and ST 28) (MICs1.56?25 ug/ml). This compound exhibited antimicrobial activity against Micrococcus luteus ATCC 9341 and Bacillus subtilis PCI 219 (MICs3.13?25 ug/ml) but not against Klebsiella pneumoniae PCI 602 and Pseudomonas aeruginosa IFO 3445.

Amount:


					529JR7020Z

ISOTRIFOLIOL

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

ISOTRIFOLIOL was shown through anticoagulative assay to have significant antithrombotic activity.


					OEL77NM46K

ALLOLICOISOFLAVONE A

CONSTITUENT ALWAYS PRESENT -> PARENT


					JW8U2YD8JL

LICORISOFLAVAN A

CONSTITUENT ALWAYS PRESENT -> PARENT

Amount:


					6XTP69UV3S

GANCAONIN I

CONSTITUENT ALWAYS PRESENT -> PARENT

Amount:


					T6ZF2ZY8CW

GLYASPERIN D

CONSTITUENT ALWAYS PRESENT -> PARENT

Amount:


					53ZZF57X0U

4',7-DIHYDROXYFLAVONE

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

7,4'-dihydroxyflavone was tested for antithrombotic activity.


					5AB6MJY2RS

URALSAPONIN O

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

The compound did not show significant cytotoxicity against uninfected MDCK cells at 100 uM, but showed inhibitory activity against the H1N1 virus at 100 uM. The compound was also evaluated for anti-HIV activity.

Amount:


					C9HP2S2FTV

URALSAPONIN S

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

Anti-H1N1 (IC50 in uM) activity of compound was shown to be 42.7 uM. The compound did not show significant cytotoxicity against uninfected MDCK cells at 100 uM, but showed inhibitory activity against the H1N1 virus at 100 uM. The compound was also evaluated for anti-HIV activity.

Amount:


					U6BLS4D8ER

URALSAPONIN R

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

Amount:


					6FO62043WK

GLYCYRRHIZIN

CONSTITUENT ALWAYS PRESENT -> PARENT


					T0O79T74CD

LIQUIRITIN

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

LIQUIRITIN was tested for antimicrobial activity against methicillin sensitive Staphylococcus aureus, methicillin resistant S. aureus, Micrococcus luteus, Bacillus subtilis, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa and found to be inactive.


					994BQ9M3AV

GLYCYRIN

CONSTITUENT ALWAYS PRESENT -> PARENT


					VFH398C4TK

ACETOXYGLYCYRRHIZIN, 22.BETA.-

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

Anti-H1N1 (IC50 in uM) activity of compound was shown to be 49.1 uM. Anti-HIV (IC50 in uM) activity of compound was shown to be 29.5 uM. The compound did not show significant cytotoxicity against uninfected MDCK cells at 100 uM, but showed inhibitory activity against the H1N1 virus at 100 uM. The compound was also evaluated for anti-HIV activity.

Amount:


					B9CTI9GB8F

TRIHYDROXYCHALCONE

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

isoliquiritigenin was tested for antithrombotic activity.


					WHP2V35GJ6

GLYCYCARPAN

CONSTITUENT ALWAYS PRESENT -> PARENT

Amount:


					88G00OJY89

LICORICESAPONIN A3

CONSTITUENT ALWAYS PRESENT -> PARENT


					8T57TH2CCD

LIQUIRITIN APIOSIDE

CONSTITUENT ALWAYS PRESENT -> PARENT


					80H8MSZ44I

DEHYDROGLYASPERIN C

CONSTITUENT ALWAYS PRESENT -> PARENT


					053L27O50V

URALSAPONIN F

CONSTITUENT ALWAYS PRESENT -> PARENT


					ULU5RJ2785

URALSAPONIN T

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

Anti-H1N1 (IC50 in uM) activity of compound was shown to be 39.6 uM. The compound did not show significant cytotoxicity against uninfected MDCK cells at 100 uM, but showed inhibitory activity against the H1N1 virus at 100 uM. The compound was also evaluated for anti-HIV activity.

Amount:


					F8A8T0J4QB

GLYASPERIN F

CONSTITUENT ALWAYS PRESENT -> PARENT


					T8X3270QWW

LICORICONE

CONSTITUENT ALWAYS PRESENT -> PARENT


					9JHS2AVR43

VESTITOL, (-)-

CONSTITUENT ALWAYS PRESENT -> PARENT


					2X3XC4R8BP

LICORICESAPONIN J2

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

Amount:


					2BU15C47BB

URALSAPONIN Y

CONSTITUENT ALWAYS PRESENT -> PARENT


					295DQC67BJ

FORMONONETIN

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

FORMONONETIN was tested for antimicrobial activity against methicillin sensitive Staphylococcus aureus, methicillin resistant S. aureus, Micrococcus luteus, Bacillus subtilis, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa and found to be inactive.


					HH9RL35865

3-O-(.BETA.-D-GLUCURONOPYRANOSYL-(1->2)-.BETA.-D-GALACTOPYRANOSYL)GLYCYRRHETIC ACID

CONSTITUENT ALWAYS PRESENT -> PARENT


					V5BY9UB2VK

EDUDIOL

CONSTITUENT ALWAYS PRESENT -> PARENT

Amount:


					NS2DFK8U3Y

URALSAPONIN Q

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

Amount:


					58NM254N9T

ISOANGUSTONE A

ACTIVE CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

The compound showed strong ferric reducing activities and effectively scavenged DPPH, ABTS+, and singlet oxygen radicals.

Amount:


					UN6XX5B366

URALSAPONIN N

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

Amount:


					KY5XP9AS2M

LICOARYLCOUMARIN

CONSTITUENT ALWAYS PRESENT -> PARENT

Amount:


					T9TP371NFX

SEMILICOISOFLAVONE B

CONSTITUENT ALWAYS PRESENT -> PARENT


					0HDJ1A004S

URALSAPONIN V

CONSTITUENT ALWAYS PRESENT -> PARENT


					EFB3Z7MN3P

LICOCOUMARONE

CONSTITUENT ALWAYS PRESENT -> PARENT

Amount:


					1CW86HCS2A

URALSAPONIN C

CONSTITUENT ALWAYS PRESENT -> PARENT


					PW27SD8M92

URALSAPONIN P

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

Amount:


					T194LKP9W6

LIQUIRITIGENIN

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

LIQUIRITIGENIN was tested for antithrombotic activity.


					L8QT245VO6

URALSAPONIN W

CONSTITUENT ALWAYS PRESENT -> PARENT


					PF9RBL8YHN

URALSAPONIN X

CONSTITUENT ALWAYS PRESENT -> PARENT


					CWQ2B8G346

GLYCYCOUMARIN

CONSTITUENT ALWAYS PRESENT -> PARENT

Amount:


					7HUT4ZWQ22

GANCAONOL B

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

GANCAONOL B was tested for antimicrobial activity against methicillin sensitive Staphylococcus aureus, methicillin resistant S. aureus, Micrococcus luteus, Bacillus subtilis, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa and found to be inactive.

Amount:

GLYCYRRHIZA URALENSIS (LICORICE) ROOT EXTRACT

SUB_CONCEPT->SUBSTANCE


					3BA9J47AGH

LICORICESAPONIN K2

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

Structure elucidation of compound.

Amount:


					6C3DSA537F

GLYCYROL

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

NEOGLYCYROL was tested for antithrombotic activity.

Amount:


					929XTD20VK

LICORICIDIN

CONSTITUENT ALWAYS PRESENT -> PARENT


					LR156FQ2XS

LICOISOFLAVONE B

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

LICOISOFLAVONE B showed 12.5 ug/ml MIC against methicillin-resistant Staphylococcus aureus and not determined for all others.


					9DR3EAN2PI

ISOGLYCYROL

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

ISOGLYCYROL was tested for antimicrobial activity against methicillin sensitive Staphylococcus aureus, methicillin resistant S. aureus, Micrococcus luteus, Bacillus subtilis, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa and found to be inactive.


					6TX086I6IG

MEDICARPIN

CONSTITUENT ALWAYS PRESENT -> PARENT


					HT2MUA8H8Z

URALSAPONIN U

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

Amount:


					3S8Z1S3G4I

3-O-METHYLGLYCYROL

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

3-O-methylglycyrol showed a MIC of >16 ug/ml for antimicrobial activities against methicillin sensitive Staphylococcus aureus, methicillin resistant S. aureus, Micrococcus luteus, Bacillus subtilis, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa.


					85CR4734XV

GLYASPERIN C

CONSTITUENT ALWAYS PRESENT -> PARENT

Amount:


					3VCU7FL2GT

LICORICESAPONIN C2

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

Structure elucidation of compound.

Amount:


					U4JQ9U5MEF

1-METHOXYFICIFOLINOL

CONSTITUENT ALWAYS PRESENT -> PARENT

Amount:


					N265YUZ764

DEHYDROGLYASPERIN D

CONSTITUENT ALWAYS PRESENT -> PARENT


					3TOQ2I088A

LICORICESAPONIN G2

CONSTITUENT ALWAYS PRESENT -> PARENT


					BP0AR0WUZQ

LICORICESAPONIN E2

CONSTITUENT ALWAYS PRESENT -> PARENT


					5FAQ11412T

JARANOL

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

JARANOL was tested for antithrombotic activity.


					SY5TBS2UJ6

URALSAPONIN M

CONSTITUENT ALWAYS PRESENT -> PARENT

Comments:

Anti-H1N1 (IC50 in uM) activity of compound was shown to be 48.0 uM. The compound did not show significant cytotoxicity against uninfected MDCK cells at 100 uM, but showed inhibitory activity against the H1N1 virus at 100 uM. The compound was also evaluated for anti-HIV activity.

Amount:


					3FU3I4IW5K

KANZONOL P

CONSTITUENT ALWAYS PRESENT -> PARENT