U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

1999
174
Substance Class Structurally Diverse
Created
by admin
on Fri Dec 15 17:03:23 GMT 2023
Edited
by admin
on Fri Dec 15 17:03:23 GMT 2023
Source Materials Class ORGANISM
Source Materials Type PLANT
Source Materials Parent
GLYCYRRHIZA GLABRA WHOLE
Part RHIZOME; ROOT; STOLON
Record UNII
2788Z9758H
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
GLYCYRRHIZA GLABRA
HPUS  
Common Name English
GLYCYRRHIZA GLABRA RHIZOME
WHO-DD  
Common Name English
Glycyrrhiza glabra rhizome [WHO-DD]
Common Name English
GLYCYRRHIZA VIOLACEA ROOT
Common Name English
RUSSIAN LICORICE ROOT
Common Name English
GLYCYRRHIZA GLABRA (LICORICE) RHIZOME/ROOT [INCI]
Common Name English
LIQUORICE [MART.]
Common Name English
Glycyrrhiza glabra extract [WHO-DD]
Common Name English
LIQUORICE ROOT (GLYCYRRHIZA GLABRA)
Common Name English
GLYCYRRHIZA GLABRA ROOT
WHO-DD  
Common Name English
Glycyrrhiza glabra root powder [WHO-DD]
Common Name English
GLYCYRRHIZA GLABRA ROOT WITH RHIZOME
WHO-DD  
Common Name English
GLYCYRRHIZA [MI]
Common Name English
YASHTIMADHU ROOT
Common Name English
SPANISH LICORICE ROOT
Common Name English
GLYCYRRHIZAE RADIX ET RHIZOMA (GLYCYRRHIZA GLABRA)
CHP  
Common Name English
GLYCYRRHIZA GLABRA [HPUS]
Common Name English
GANCAO (GLYCYRRHIZA GLABRA)
Common Name English
GLYCYRRHIZA GLABRA (LICORICE) ROOT [INCI]
Common Name English
GLYCYRRHIZA GLANDULIFERA ROOT
Common Name English
GLYCYRRHIZA HIRSUTA ROOT
Common Name English
LIQUIRITIAE RADIX
Common Name English
GUANG GUO GAN CAO ROOT
Common Name English
GLYCYRRHIZAE RADIX ET RHIZOMA (GLYCYRRHIZA GLABRA) [CHP]
Common Name English
FEMA NO. 2630
Code English
GLYCYRRHIZA (GLYCYRRHIZA GLABRA) [JP]
Common Name English
TURKISH LICORICE ROOT
Common Name English
GLYCYRRHIZA GLABRA (LICORICE) RHIZOME/ROOT
INCI  
INCI  
Official Name English
Glycyrrhiza glabra root [WHO-DD]
Common Name English
CULTIVATED LICORICE ROOT
Common Name English
Glycyrrhiza glabra root with rhizome [WHO-DD]
Common Name English
LICORICE [FHFI]
Common Name English
GLYCYRRHIZA GLABRA ROOT POWDER
WHO-DD  
Common Name English
GLYCYRRHIZA PALLIDA ROOT
Common Name English
GLYCYRRHIZA GLABRA (LICORICE) ROOT
INCI  
INCI  
Official Name English
GAN CAO ROOT
Common Name English
Classification Tree Code System Code
NDF-RT N0000185375
Created by admin on Fri Dec 15 17:03:24 GMT 2023 , Edited by admin on Fri Dec 15 17:03:24 GMT 2023
NCI_THESAURUS C79664
Created by admin on Fri Dec 15 17:03:23 GMT 2023 , Edited by admin on Fri Dec 15 17:03:23 GMT 2023
NDF-RT N0000185371
Created by admin on Fri Dec 15 17:03:23 GMT 2023 , Edited by admin on Fri Dec 15 17:03:23 GMT 2023
Code System Code Type Description
DAILYMED
2788Z9758H
Created by admin on Fri Dec 15 17:03:23 GMT 2023 , Edited by admin on Fri Dec 15 17:03:23 GMT 2023
PRIMARY
RXCUI
1010954
Created by admin on Fri Dec 15 17:03:24 GMT 2023 , Edited by admin on Fri Dec 15 17:03:24 GMT 2023
PRIMARY
RXCUI
1370435
Created by admin on Fri Dec 15 17:03:24 GMT 2023 , Edited by admin on Fri Dec 15 17:03:24 GMT 2023
ALTERNATIVE
FDA UNII
2788Z9758H
Created by admin on Fri Dec 15 17:03:23 GMT 2023 , Edited by admin on Fri Dec 15 17:03:23 GMT 2023
PRIMARY
NDF-RT
N0000008246
Created by admin on Fri Dec 15 17:03:23 GMT 2023 , Edited by admin on Fri Dec 15 17:03:23 GMT 2023
PRIMARY Plant Proteins [Chemical/Ingredient]
EVMPD
SUB33808
Created by admin on Fri Dec 15 17:03:23 GMT 2023 , Edited by admin on Fri Dec 15 17:03:23 GMT 2023
PRIMARY
EVMPD
SUB32404
Created by admin on Fri Dec 15 17:03:23 GMT 2023 , Edited by admin on Fri Dec 15 17:03:23 GMT 2023
PRIMARY
NDF-RT
N0000175629
Created by admin on Fri Dec 15 17:03:23 GMT 2023 , Edited by admin on Fri Dec 15 17:03:23 GMT 2023
PRIMARY Increased Histamine Release [PE]
EMA ASSESSMENT REPORTS
GLYCYRRHIZA GLABRA
Created by admin on Fri Dec 15 17:03:23 GMT 2023 , Edited by admin on Fri Dec 15 17:03:23 GMT 2023
PRIMARY
EVMPD
SUB14003MIG
Created by admin on Fri Dec 15 17:03:23 GMT 2023 , Edited by admin on Fri Dec 15 17:03:23 GMT 2023
PRIMARY
NDF-RT
N0000184306
Created by admin on Fri Dec 15 17:03:23 GMT 2023 , Edited by admin on Fri Dec 15 17:03:23 GMT 2023
PRIMARY Cell-mediated Immunity [PE]
DRUG BANK
DB14312
Created by admin on Fri Dec 15 17:03:23 GMT 2023 , Edited by admin on Fri Dec 15 17:03:23 GMT 2023
PRIMARY
NDF-RT
N0000007512
Created by admin on Fri Dec 15 17:03:23 GMT 2023 , Edited by admin on Fri Dec 15 17:03:23 GMT 2023
PRIMARY Dietary Proteins [Chemical/Ingredient]
NDF-RT
N0000171131
Created by admin on Fri Dec 15 17:03:23 GMT 2023 , Edited by admin on Fri Dec 15 17:03:23 GMT 2023
PRIMARY Allergens [Chemical/Ingredient]
CAS
84775-66-6
Created by admin on Fri Dec 15 17:03:23 GMT 2023 , Edited by admin on Fri Dec 15 17:03:23 GMT 2023
PRIMARY
NCI_THESAURUS
C80295
Created by admin on Fri Dec 15 17:03:23 GMT 2023 , Edited by admin on Fri Dec 15 17:03:23 GMT 2023
PRIMARY
MERCK INDEX
m5810
Created by admin on Fri Dec 15 17:03:23 GMT 2023 , Edited by admin on Fri Dec 15 17:03:23 GMT 2023
PRIMARY Merck Index
EVMPD
SUB15103MIG
Created by admin on Fri Dec 15 17:03:23 GMT 2023 , Edited by admin on Fri Dec 15 17:03:23 GMT 2023
ALTERNATIVE
Related Record Type Details
Structure of HISPAGLABRIDIN A
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of LIQUIRITIGENIN
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of GLABROCOUMARONE A
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of 4'-O-METHYLGLABRIDIN
CONSTITUENT ALWAYS PRESENT -> PARENT
Minimum Inhibitory Concentration (MIC) for Staphylococcus aureus (ATCC 13709) = 6.25 mcg ml and Mycobacterium smegmatis (ATCC 6371) = 3.12 mcg ml. Extracts of G. glabra var. typica (Spanish licorice)-but not var. grandulifera (Russian licorice) were repeatedly active in the screen.
Structure of SHINPTEROCARPIN
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of GLYCYRIN
CONSTITUENT ALWAYS PRESENT -> PARENT
Coumarin
Structure of ISOLIQUIRITIN
CONSTITUENT ALWAYS PRESENT -> PARENT
LICORICE EXTRACT POWDER
SUB_CONCEPT->SUBSTANCE
Structure of LICOFLAVONOL
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of 7-METHOXYCOUMARIN
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of GLABRENE
CONSTITUENT ALWAYS PRESENT -> PARENT
GLABRENE showed antibacterial activity against MSSAs (strains FDA 209P and Smith) and MRSAs(strains K3 and ST 28) (MICs 1.56?25 ug/ml). This compound exhibited antimicrobial activity against Micrococcus luteus ATCC 9341 and Bacillus subtilis PCI 219 (MICs 3.13?25 ug/ml) but not against Klebsiella pneumoniae PCI 602 and Pseudomonas aeruginosa IFO 3445.
Structure of NEOLIQUIRITIN
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of LICOPYRANOCOUMARIN
CONSTITUENT ALWAYS PRESENT -> PARENT
Coumarin
Structure of NEOISOLIQUIRITINE
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of LICURASIDE
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of HISPAGLABRIDIN B
CONSTITUENT ALWAYS PRESENT -> PARENT
Minimum Inhibitory Concentration (MIC) for Staphylococcus aureus (ATCC 13709) = 6.25 mcg ml and Mycobacterium smegmatis (ATCC 6371) = 3.12 mcg ml. Extracts of G. glabra var. typica (Spanish licorice)-but not var. grandulifera (Russian licorice) were repeatedly active in the screen.
Structure of PARATOCARPIN B
CONSTITUENT ALWAYS PRESENT -> PARENT
A group of neolignan lipid esters and phenolic compounds isolated from the roots and stolons of liquorice (Glycyrrhiza glabra) were found to have chemopreventive properties. Of these compounds, hispaglabridin B isoliquiritigenin, and paratocarpin B were found to be the most potent anti-oxidant agents (Chin et al. 2007).
GLYCYRRHIZA GLABRA L RHIZOME EXTRACT
SUB_CONCEPT->SUBSTANCE
Structure of OROXINDIN
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of LIQCOUMARIN
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of 3'-METHOXYGLABRADIN
CONSTITUENT ALWAYS PRESENT -> PARENT
Minimum Inhibitory Concentration (MIC) for Staphylococcus aureus (ATCC 13709) = 50 mcg ml. Extracts of G. glabra var. typica (Spanish licorice)-but not var. grandulifera (Russian licorice) were repeatedly active in the screen.
Structure of FORMONONETIN
CONSTITUENT ALWAYS PRESENT -> PARENT
Showed no inhibition at 100 mcg/ml for Staphylococcus aureus (ATCC 13709) and Mycobacterium smegmatis (ATCC 6371). Extracts of G. glabra var. typica (Spanish licorice)-but not var. grandulifera (Russian licorice) were repeatedly active in the screen.
Structure of GLABROCOUMARIN
CONSTITUENT ALWAYS PRESENT -> PARENT
Coumarin
Structure of PHASEOLLINISOFLAVAN
CONSTITUENT ALWAYS PRESENT -> PARENT
Minimum Inhibitory Concentration (MIC) for Staphylococcus aureus (ATCC 13709) = 25 mcg ml and Mycobacterium smegmatis (ATCC 6371) = 2.5 mcg ml. Extracts of G. glabra var. typica (Spanish licorice)-but not var. grandulifera (Russian licorice) were repeatedly active in the screen.
Structure of UMBELLIFERONE
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of GLABROCOUMARONE B
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of LICOFURANOCOUMARIN
CONSTITUENT ALWAYS PRESENT -> PARENT
Coumarin
Structure of LICOISOFLAVONE B
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of GLABROL
CONSTITUENT ALWAYS PRESENT -> PARENT
Minimum Inhibitory Concentration (MIC) for Staphylococcus aureus (ATCC 13709) = 1.56 mcg ml and Mycobacterium smegmatis (ATCC 6371) = 1.56 mcg ml. Extracts of G. glabra var. typica (Spanish licorice)-but not var. grandulifera (Russian licorice) were repeatedly active in the screen.
ALLERGENIC EXTRACT- LICORICE GLYCYRRHIZA GLABRA
SUB_CONCEPT->SUBSTANCE
Structure of GLYZARIN
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of GLABRIDIN
CONSTITUENT ALWAYS PRESENT -> PARENT
Anti-HCV activity IC50 was found to be be 6.2 ug/mL.
Structure of HEMILEIOCARPIN
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of GLABROLIDE
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of GLYCHIONIDE A
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of AMMONIUM GLYCYRRHIZATE
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of LIQUIRITIN
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of TRIHYDROXYCHALCONE
CONSTITUENT ALWAYS PRESENT -> PARENT
A group of neolignan lipid esters and phenolic compounds isolated from the roots and stolons of liquorice (Glycyrrhiza glabra) were found to have chemopreventive properties. Of these compounds, hispaglabridin B isoliquiritigenin, and paratocarpin B were found to be the most potent anti-oxidant agents (Chin et al. 2007).
Structure of GLABRONE
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of JARANOL
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of ENOXOLONE
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of GLYCYRRHIZINATE DIPOTASSIUM
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of Phenol
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of 3-HYDROXYGLABROL
CONSTITUENT ALWAYS PRESENT -> PARENT
Minimum Inhibitory Concentration (MIC) for Staphylococcus aureus (ATCC 13709) = 6.25 mcg ml and Mycobacterium smegmatis (ATCC 6371) = 6.25 mcg ml. Extracts of G. glabra var. typica (Spanish licorice)-but not var. grandulifera (Russian licorice) were repeatedly active in the screen.
GLYCYRRHIZA GLABRA (LICORICE) ROOT POWDER
SUB_CONCEPT->SUBSTANCE
Structure of LICOISOFLAVONE A
CONSTITUENT ALWAYS PRESENT -> PARENT
Related Record Type Details
GLYCYRRHIZA GLABRA
ACTIVE MOIETY
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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