ACEPROMETAZINE

Possibly Marketed Outside US

Details

Stereochemistry	RACEMIC
Molecular Formula	C19H22N2OS
Molecular Weight	326.456
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(CN1C2=C(SC3=C1C=C(C=C3)C(C)=O)C=CC=C2)N(C)C

InChI

InChIKey=XLOQNFNTQIRSOX-UHFFFAOYSA-N

InChI=1S/C19H22N2OS/c1-13(20(3)4)12-21-16-7-5-6-8-18(16)23-19-10-9-15(14(2)22)11-17(19)21/h5-11,13H,12H2,1-4H3

HIDE SMILES / InChI

Molecular Formula	C19H22N2OS
Molecular Weight	326.456
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.bocsci.com/aceprometazine-cas-13461-01-3-item-245044.html | https://www.has-sante.fr/portail/upload/docs/application/pdf/2011-06/mepronizine_-_ct-8952.pdf | Plunkett, S.J. (2013) Emergency Procedures for the Small Animal Veterinarian, page 127, retrieved from: https://books.google.ru/books?id=XvwK4gU_VCcC | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 4, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ

Aceprometazine is neuroleptic agent, sedative and antitussive drug. It is a Histamine H1 receptor antagonist as an approved drug. It can be used in combination with meprobamate for the treatment of sleep disorders such as Insomnia. Acepromazine can cause venodilation and hypotension.

Approval Year

PubMed

Title	Date	PubMed
Risk of syncope in the elderly and consumption of drugs: a case-control study.	1997 Mar	9120531
Abusive prescription of psychostimulants: a study of two cases.	2006 Mar	16566781

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 18:03:04 GMT 2023` Edited by `admin` on `Sat Dec 16 18:03:04 GMT 2023`
Record UNII	984N9YTM4Y
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ACEPROMETAZINE

Official Name

English

ACEPROMETAZINE [MART.]

Common Name

English

CB-1664

Code

English

CB 1664

Code

English

Aceprometazine [WHO-DD]

Common Name

English

aceprometazine [INN]

Common Name

English

10-(2-(DIMETHYLAMINO)PROPYL)PHENOTHIAZIN-2-YL METHYL KETONE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265