ACEPROMETAZINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Possibly Marketed Outside US

Details

Stereochemistry	RACEMIC
Molecular Formula	C19H22N2OS
Molecular Weight	326.456
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ACEPROMETAZINE

Structure Search

SMILES

CC(CN1C2=C(SC3=C1C=C(C=C3)C(C)=O)C=CC=C2)N(C)C

InChI

InChIKey=XLOQNFNTQIRSOX-UHFFFAOYSA-N

InChI=1S/C19H22N2OS/c1-13(20(3)4)12-21-16-7-5-6-8-18(16)23-19-10-9-15(14(2)22)11-17(19)21/h5-11,13H,12H2,1-4H3

HIDE SMILES / InChI

Molecular Formula	C19H22N2OS
Molecular Weight	326.456
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.bocsci.com/aceprometazine-cas-13461-01-3-item-245044.html | https://www.has-sante.fr/portail/upload/docs/application/pdf/2011-06/mepronizine_-_ct-8952.pdf | Plunkett, S.J. (2013) Emergency Procedures for the Small Animal Veterinarian, page 127, retrieved from: https://books.google.ru/books?id=XvwK4gU_VCcC | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 4, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ

Aceprometazine is neuroleptic agent, sedative and antitussive drug. It is a Histamine H1 receptor antagonist as an approved drug. It can be used in combination with meprobamate for the treatment of sleep disorders such as Insomnia. Acepromazine can cause venodilation and hypotension.

Approval Year

PubMed

PubMed

Title	Date	PubMed

Patents

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 18:03:04 UTC 2023` Edited by `admin` on `Sat Dec 16 18:03:04 UTC 2023`
Record UNII	984N9YTM4Y
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ACEPROMETAZINE

Official Name

English

ACEPROMETAZINE [MART.]

Common Name

English

CB-1664

Code

English

CB 1664

Code

English

Aceprometazine [WHO-DD]

Common Name

English

aceprometazine [INN]

Common Name

English

10-(2-(DIMETHYLAMINO)PROPYL)PHENOTHIAZIN-2-YL METHYL KETONE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265

Created by admin on Sat Dec 16 18:03:05 UTC 2023 , Edited by admin on Sat Dec 16 18:03:05 UTC 2023

Code System Code Type Description

ChEMBL

CHEMBL2104054

Created by admin on Sat Dec 16 18:03:05 UTC 2023 , Edited by admin on Sat Dec 16 18:03:05 UTC 2023

PRIMARY

PUBCHEM

26035

Created by admin on Sat Dec 16 18:03:05 UTC 2023 , Edited by admin on Sat Dec 16 18:03:05 UTC 2023

PRIMARY

CHEBI

53770

Created by admin on Sat Dec 16 18:03:05 UTC 2023 , Edited by admin on Sat Dec 16 18:03:05 UTC 2023

PRIMARY

EVMPD

SUB05214MIG

Created by admin on Sat Dec 16 18:03:05 UTC 2023 , Edited by admin on Sat Dec 16 18:03:05 UTC 2023

PRIMARY

DRUG BANK

DB01615

Created by admin on Sat Dec 16 18:03:05 UTC 2023 , Edited by admin on Sat Dec 16 18:03:05 UTC 2023

PRIMARY

RXCUI

161203

Created by admin on Sat Dec 16 18:03:05 UTC 2023 , Edited by admin on Sat Dec 16 18:03:05 UTC 2023

PRIMARY

RxNorm

SMS_ID

100000087934

Created by admin on Sat Dec 16 18:03:05 UTC 2023 , Edited by admin on Sat Dec 16 18:03:05 UTC 2023

PRIMARY

EPA CompTox

DTXSID00864407

Created by admin on Sat Dec 16 18:03:05 UTC 2023 , Edited by admin on Sat Dec 16 18:03:05 UTC 2023

PRIMARY

ECHA (EC/EINECS)

236-661-9

Created by admin on Sat Dec 16 18:03:05 UTC 2023 , Edited by admin on Sat Dec 16 18:03:05 UTC 2023

PRIMARY

INN

1921

Created by admin on Sat Dec 16 18:03:05 UTC 2023 , Edited by admin on Sat Dec 16 18:03:05 UTC 2023

PRIMARY

DRUG CENTRAL

50

Created by admin on Sat Dec 16 18:03:05 UTC 2023 , Edited by admin on Sat Dec 16 18:03:05 UTC 2023

PRIMARY

MESH

C021280

Created by admin on Sat Dec 16 18:03:05 UTC 2023 , Edited by admin on Sat Dec 16 18:03:05 UTC 2023

PRIMARY

CAS

13461-01-3

Created by admin on Sat Dec 16 18:03:05 UTC 2023 , Edited by admin on Sat Dec 16 18:03:05 UTC 2023

PRIMARY

WIKIPEDIA

ACEPROMETAZINE

Created by admin on Sat Dec 16 18:03:05 UTC 2023 , Edited by admin on Sat Dec 16 18:03:05 UTC 2023

PRIMARY

FDA UNII

984N9YTM4Y

Created by admin on Sat Dec 16 18:03:05 UTC 2023 , Edited by admin on Sat Dec 16 18:03:05 UTC 2023

PRIMARY

NCI_THESAURUS

C72678

Created by admin on Sat Dec 16 18:03:05 UTC 2023 , Edited by admin on Sat Dec 16 18:03:05 UTC 2023

PRIMARY

Related Record Type Details


					TJ08QTQ1E8

ACEPROMETAZINE, (S)-

ENANTIOMER -> RACEMATE


					919V0YJO5O

ACEPROMETAZINE, (R)-

ENANTIOMER -> RACEMATE


					A462855RC7

ACEPROMETAZINE MALEATE

SALT/SOLVATE -> PARENT

Related Record Type Details


					984N9YTM4Y

ACTIVE MOIETY