ACEPROMETAZINE MALEATE

Possibly Marketed Outside US

Details

Stereochemistry	RACEMIC
Molecular Formula	C19H22N2OS.C4H4O4
Molecular Weight	442.528
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)\C=C/C(O)=O.CC(CN1C2=C(SC3=C1C=C(C=C3)C(C)=O)C=CC=C2)N(C)C

InChI

InChIKey=BACHEZCVYSHWLT-BTJKTKAUSA-N

InChI=1S/C19H22N2OS.C4H4O4/c1-13(20(3)4)12-21-16-7-5-6-8-18(16)23-19-10-9-15(14(2)22)11-17(19)21;5-3(6)1-2-4(7)8/h5-11,13H,12H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

HIDE SMILES / InChI

Molecular Formula	C4H4O4
Molecular Weight	116.0722
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Molecular Formula	C19H22N2OS
Molecular Weight	326.456
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.bocsci.com/aceprometazine-cas-13461-01-3-item-245044.html | https://www.has-sante.fr/portail/upload/docs/application/pdf/2011-06/mepronizine_-_ct-8952.pdf | Plunkett, S.J. (2013) Emergency Procedures for the Small Animal Veterinarian, page 127, retrieved from: https://books.google.ru/books?id=XvwK4gU_VCcC | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 4, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ

Aceprometazine is neuroleptic agent, sedative and antitussive drug. It is a Histamine H1 receptor antagonist as an approved drug. It can be used in combination with meprobamate for the treatment of sleep disorders such as Insomnia. Acepromazine can cause venodilation and hypotension.

Approval Year

PubMed

Title	Date	PubMed

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 20:16:33 GMT 2023` Edited by `admin` on `Fri Dec 15 20:16:33 GMT 2023`
Record UNII	A462855RC7
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ACEPROMETAZINE MALEATE

Common Name

English

Aceprometazine maleate [WHO-DD]

Common Name

English

ACEPROMETAZINE MALEATE COMPONENT OF CLINDORM

Brand Name

English

MEPRONIZINE, ACEPROMETAZINE MALEATE COMPONENT

Brand Name

English

SUPPONIZINE, ACEPROMETAZINE MALEATE COMPONENT

Brand Name

English

CLINDORM, ACEPROMETAZINE MALEATE COMPONENT

Brand Name

English

ETHANONE, 1-(10-(2-(DIMETHYLAMINO)PROPYL)-10H-PHENOTHIAZIN-2-YL)-, (2Z)-2-BUTENEDIOATE (1:1)

Systematic Name

English

Code System Code Type Description

PUBCHEM

25087112