CHLORPROETHAZINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H23ClN2S
Molecular Weight	346.917
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of CHLORPROETHAZINE

Structure Search

SMILES

CCN(CC)CCCN1C2=CC(Cl)=CC=C2SC3=C1C=CC=C3

InChI

InChIKey=DBOUGBAQLIXZLV-UHFFFAOYSA-N

InChI=1S/C19H23ClN2S/c1-3-21(4-2)12-7-13-22-16-8-5-6-9-18(16)23-19-11-10-15(20)14-17(19)22/h5-6,8-11,14H,3-4,7,12-13H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C19H23ClN2S
Molecular Weight	346.917
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.drugs.com/international/chlorproethazine.html | https://www.ncbi.nlm.nih.gov/pubmed/13958556 | https://www.ncbi.nlm.nih.gov/pubmed/5324919 | https://www.ncbi.nlm.nih.gov/pubmed/18201351

Chlorproethazine (Neuriplege) is a neuroleptic, antipsychotic and muscle relaxant. Neuriplege® cream was available as a non‐prescription medication in France until its withdrawal from the market by regulatory authorities in January 2007. Neuriplege caused phototoxicity and photocontact allergy.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
Contact sensitization to chlorproethazine can induce persistent light reaction and cross-photoreactions to other phenothiazines.	2001 Jun	11417527
Combined quinacrine and chlorpromazine therapy in fatal familial insomnia.	2004 Jul-Aug	15319710
Photocontact allergic and phototoxic studies of chlorproethazine.	2008 Feb	18201351
Comparative effects of cationic triarylmethane, phenoxazine and phenothiazine dyes on horse serum butyrylcholinesterase.	2008 Oct 15	18656440

Patents

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:52:21 GMT 2023` Edited by `admin` on `Sat Dec 16 16:52:21 GMT 2023`
Record UNII	960NX27Z07
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CHLORPROETHAZINE

Official Name

English

chlorproethazine [INN]

Common Name

English

Chlorproethazine [WHO-DD]

Common Name

English

CHLORPROETHAZINE [MI]

Common Name

English

2-CHLORO-10-(3-DIETHYLAMINOPROPYL)PHENOTHIAZINE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66880

Created by admin on Sat Dec 16 16:52:21 GMT 2023 , Edited by admin on Sat Dec 16 16:52:21 GMT 2023

WHO-VATC

QN05AA07

Created by admin on Sat Dec 16 16:52:21 GMT 2023 , Edited by admin on Sat Dec 16 16:52:21 GMT 2023

WHO-ATC

N05AA07

Created by admin on Sat Dec 16 16:52:21 GMT 2023 , Edited by admin on Sat Dec 16 16:52:21 GMT 2023

Code System Code Type Description

INN

1147

Created by admin on Sat Dec 16 16:52:21 GMT 2023 , Edited by admin on Sat Dec 16 16:52:21 GMT 2023

PRIMARY

ECHA (EC/EINECS)

201-510-8

Created by admin on Sat Dec 16 16:52:21 GMT 2023 , Edited by admin on Sat Dec 16 16:52:21 GMT 2023

PRIMARY

SMS_ID

100000081893

Created by admin on Sat Dec 16 16:52:21 GMT 2023 , Edited by admin on Sat Dec 16 16:52:21 GMT 2023

PRIMARY

DRUG CENTRAL

619

Created by admin on Sat Dec 16 16:52:21 GMT 2023 , Edited by admin on Sat Dec 16 16:52:21 GMT 2023

PRIMARY

CAS

84-01-5

Created by admin on Sat Dec 16 16:52:21 GMT 2023 , Edited by admin on Sat Dec 16 16:52:21 GMT 2023

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DRUG BANK

DB13382

Created by admin on Sat Dec 16 16:52:21 GMT 2023 , Edited by admin on Sat Dec 16 16:52:21 GMT 2023

PRIMARY

WIKIPEDIA

CHLORPROETHAZINE

Created by admin on Sat Dec 16 16:52:21 GMT 2023 , Edited by admin on Sat Dec 16 16:52:21 GMT 2023

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FDA UNII

960NX27Z07

Created by admin on Sat Dec 16 16:52:21 GMT 2023 , Edited by admin on Sat Dec 16 16:52:21 GMT 2023

PRIMARY

NCI_THESAURUS

C79580

Created by admin on Sat Dec 16 16:52:21 GMT 2023 , Edited by admin on Sat Dec 16 16:52:21 GMT 2023

PRIMARY

ChEMBL

CHEMBL52125

Created by admin on Sat Dec 16 16:52:21 GMT 2023 , Edited by admin on Sat Dec 16 16:52:21 GMT 2023

PRIMARY

MESH

C054028

Created by admin on Sat Dec 16 16:52:21 GMT 2023 , Edited by admin on Sat Dec 16 16:52:21 GMT 2023

PRIMARY

PUBCHEM

65750

Created by admin on Sat Dec 16 16:52:21 GMT 2023 , Edited by admin on Sat Dec 16 16:52:21 GMT 2023

PRIMARY

EPA CompTox

DTXSID80232882

Created by admin on Sat Dec 16 16:52:21 GMT 2023 , Edited by admin on Sat Dec 16 16:52:21 GMT 2023

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MERCK INDEX

m3459

Created by admin on Sat Dec 16 16:52:21 GMT 2023 , Edited by admin on Sat Dec 16 16:52:21 GMT 2023

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Merck Index

RXCUI

59860

Created by admin on Sat Dec 16 16:52:21 GMT 2023 , Edited by admin on Sat Dec 16 16:52:21 GMT 2023

PRIMARY

RxNorm

EVMPD

SUB06206MIG

Created by admin on Sat Dec 16 16:52:21 GMT 2023 , Edited by admin on Sat Dec 16 16:52:21 GMT 2023

PRIMARY

Related Record Type Details


					520P4U8V2Z

CHLORPROETHAZINE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Related Record Type Details


					960NX27Z07

CHLORPROETHAZINE

ACTIVE MOIETY