Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C19H23ClN2S.ClH |
| Molecular Weight | 383.378 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CCN(CC)CCCN1C2=CC=CC=C2SC3=C1C=C(Cl)C=C3
InChI
InChIKey=XXQMDKCWUYZXOF-UHFFFAOYSA-N
InChI=1S/C19H23ClN2S.ClH/c1-3-21(4-2)12-7-13-22-16-8-5-6-9-18(16)23-19-11-10-15(20)14-17(19)22;/h5-6,8-11,14H,3-4,7,12-13H2,1-2H3;1H
| Molecular Formula | C19H23ClN2S |
| Molecular Weight | 346.917 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Chlorproethazine (Neuriplege) is a neuroleptic, antipsychotic and muscle relaxant. Neuriplege® cream was available as a non‐prescription medication in France until its withdrawal from the market by regulatory authorities in January 2007. Neuriplege caused phototoxicity and photocontact allergy.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Contact sensitization to chlorproethazine can induce persistent light reaction and cross-photoreactions to other phenothiazines. | 2001 Jun |
|
| Combined quinacrine and chlorpromazine therapy in fatal familial insomnia. | 2004 Jul-Aug |
|
| Photocontact allergic and phototoxic studies of chlorproethazine. | 2008 Feb |
|
| Toxic effects of chlorpromazine on Carassius auratus and its oxidative stress. | 2008 Nov |
|
| Comparative effects of cationic triarylmethane, phenoxazine and phenothiazine dyes on horse serum butyrylcholinesterase. | 2008 Oct 15 |
|
| Hypothermia increases interleukin-6 and interleukin-10 in juvenile endotoxemic mice. | 2010 Jan |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:32:53 GMT 2023
by
admin
on
Fri Dec 15 16:32:53 GMT 2023
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| Record UNII |
520P4U8V2Z
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| Record Status |
Validated (UNII)
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NCI_THESAURUS |
C66880
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C054028
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CHEMBL52125
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ACTIVE MOIETY |