IRON DEXTRAN

Description

Ferric chloride is a compound used as a food additive, a haemostatic or treatment for hypochromic anaemia. Ferric chloride induced vascular injury is a widely used model of occlusive thrombosis that reports platelet activation and aggregation in the context of an aseptic closed vascular system. Iron i.v. ferric chloride (960 mg) has being shown to be effective in correcting anaemia in HD patients with iron deficiency.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
transformed cell apoptotic process 108	Activator 1,430
Phosphate 44	Chelating Agent 142

Conditions

Condition	Modality	Highest Phase	Product
Unknown 2,578
Unknown 2,578
Parenteral Nutrition 50	Primary	Approved 8,429	Additrace N
Iron deficiency 80	Preventing	Approved 8,429	Parmirin
Dental diseases 45	Primary	Basic research	Unknown
Iron deficiency anemia 56	Primary	Approved 8,429	SANFEROL
Unknown 2,578
Pain 614	Inactive ingredient	Approved 8,429	Oxycontin
Unknown 2,578
Radioactive cesium and/or radioactive or non-radioactive thallium internal contamination 44	Curative	Approved 8,429	RADIOGARDASE
Chronic kidney disease 56	Palliative	Approved 8,429	AURYXIA

PubMed

Show entries

Title	Date	PubMed
[Effects of ferric fluoride compounds on dental enamel].	1954 Nov 15	13224146
The formation of ferritin from apoferritin. Kinetics and mechanism of iron uptake.	1972 Jan	5075227
The formation of ferritin from apoferritin. Catalytic action of apoferritin.	1973 Oct	4797166
Contact dermatitis to yellow iron oxide.	1985 Aug	4064645
Carcinogenicity studies on natural and man-made fibres with the intraperitoneal test in rats.	1989	2744824

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Patents

Sample Use Guides

In Vivo Use Guide

Ferric sodium citrate is an additive used in various foods such as baby milk powder, school and hospital food, beverages, cereals and supplements. It is administered orally.

Route of Administration: Oral

In Vitro Use Guide

Unknown