U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C12H10N4O2
Molecular Weight 242.2339
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of S-8510 FREE BASE

SMILES

C1COCc2c1ncc3c2nc(-c4ccon4)[nH]3

InChI

InChIKey=ITPFSYAYHHPKRT-UHFFFAOYSA-N
InChI=1S/C12H10N4O2/c1-3-17-6-7-8(1)13-5-10-11(7)15-12(14-10)9-2-4-18-16-9/h2,4-5H,1,3,6H2,(H,14,15)

HIDE SMILES / InChI

Molecular Formula C12H10N4O2
Molecular Weight 242.2339
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Substance Class Chemical
Created
by admin
on Sat Jun 26 10:52:26 UTC 2021
Edited
by admin
on Sat Jun 26 10:52:26 UTC 2021
Record UNII
92SP8RX873
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
S-8510 FREE BASE
Common Name English
IMIDAZO(4,5-D)PYRANO(4,3-B)PYRIDINE, 1,6,7,9-TETRAHYDRO-2-(3-ISOXAZOLYL)-
Systematic Name English
IMIDAZO(4,5-D)PYRANO(4,3-B)PYRIDINE, 3,6,7,9-TETRAHYDRO-2-(3-ISOXAZOLYL)-
Systematic Name English
IMIDAZO(4,5-D)PYRANO(4,3-B)PYRIDINE, 1,6,7,9-TETRAHYDRO-2-(3-ISOXAZOLYL)-(ANHYDROUS)
Common Name English
Code System Code Type Description
FDA UNII
92SP8RX873
Created by admin on Sat Jun 26 10:52:26 UTC 2021 , Edited by admin on Sat Jun 26 10:52:26 UTC 2021
PRIMARY
PUBCHEM
135409387
Created by admin on Sat Jun 26 10:52:26 UTC 2021 , Edited by admin on Sat Jun 26 10:52:26 UTC 2021
PRIMARY
CAS
151224-83-8
Created by admin on Sat Jun 26 10:52:26 UTC 2021 , Edited by admin on Sat Jun 26 10:52:26 UTC 2021
PRIMARY
Related Record Type Details
TARGET->INVERSE AGONIST
Non selective GABAA inverse agonist. Therapeutic potential is limited by severe side effects (anxiogenic, convulsant, and proconvulsant).
ALLOSTERIC
Related Record Type Details
ACTIVE MOIETY