GSK-554418A

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H19ClN4O2
Molecular Weight	370.833
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1C=CC2=C(NC3=CC=CC(Cl)=C3)N=CC(C(=O)N4CCOCC4)=C12

InChI

InChIKey=VARGWBUXBMFVJN-UHFFFAOYSA-N

InChI=1S/C19H19ClN4O2/c1-23-6-5-15-17(23)16(19(25)24-7-9-26-10-8-24)12-21-18(15)22-14-4-2-3-13(20)11-14/h2-6,11-12H,7-10H2,1H3,(H,21,22)

HIDE SMILES / InChI

Molecular Formula	C19H19ClN4O2
Molecular Weight	370.833
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Discovery of 1-[4-(3-chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridin-7-yl]-1-morpholin-4-ylmethanone (GSK554418A), a brain penetrant 5-azaindole CB2 agonist for the treatment of chronic pain.	2009-10-08	19743867

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:38:30 GMT 2025` Edited by `admin` on `Mon Mar 31 22:38:30 GMT 2025`
Record UNII	9132NB1UJR
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

GSK-554418A

Common Name

English

METHANONE, (4-((3-CHLOROPHENYL)AMINO)-1-METHYL-1H-PYRROLO(3,2-C)PYRIDIN-7-YL)-4-MORPHOLINYL-

Preferred Name

English

MORPHOLINE, 4-((4-((3-CHLOROPHENYL)AMINO)-1-METHYL-1H-PYRROLO(3,2-C)PYRIDIN-7-YL)CARBONYL)-

Systematic Name

English

Code System Code Type Description

CAS

871819-90-8

Created by admin on Mon Mar 31 22:38:30 GMT 2025 , Edited by admin on Mon Mar 31 22:38:30 GMT 2025

PRIMARY

FDA UNII

9132NB1UJR

Created by admin on Mon Mar 31 22:38:30 GMT 2025 , Edited by admin on Mon Mar 31 22:38:30 GMT 2025

PRIMARY

PUBCHEM

11501580

Created by admin on Mon Mar 31 22:38:30 GMT 2025 , Edited by admin on Mon Mar 31 22:38:30 GMT 2025

PRIMARY

Related Record Type Details


					SKEU5X23RI

CANNABINOID RECEPTOR 2

TARGET -> AGONIST

Interaction Type:

AGONIST

Qualification:

EC50

Amount:

Related Record Type Details


					9132NB1UJR

GSK-554418A

ACTIVE MOIETY