PEPA

NC(=O)COC1=C(F)C=C(SCCNS(=O)(=O)C2=CC=CC=C2)C=C1F

InChIKey=GTACSIONMHMRPD-UHFFFAOYSA-N

InChI=1S/C16H16F2N2O4S2/c17-13-8-11(9-14(18)16(13)24-10-15(19)21)25-7-6-20-26(22,23)12-4-2-1-3-5-12/h1-5,8-9,20H,6-7,10H2,(H2,19,21)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Potency
Glutamate receptor ionotropic AMPA 41 Target ID: CHEMBL2096670 Sources: https://www.ncbi.nlm.nih.gov/pubmed/9221774	Positive Allosteric Modulator 179
Glutamate receptor ionotropic, AMPA 3 4 Target ID: CHEMBL3504 Sources: https://www.ncbi.nlm.nih.gov/pubmed/9221774	Positive Allosteric Modulator 179	50.0 µM [EC50]
Glutamate receptor ionotropic, AMPA 2 6 Target ID: CHEMBL3503 Sources: https://www.ncbi.nlm.nih.gov/pubmed/20199107	Positive Allosteric Modulator 179

Substance Class	Chemical Created by `admin` on `Sat Dec 16 19:04:18 GMT 2023` Edited by `admin` on `Sat Dec 16 19:04:18 GMT 2023`
Record UNII	8S4PR7A8JS
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

PEPA

Code

English

2-(2,6-DIFLUORO-4-((2-((PHENYLSULFONYL)AMINO)ETHYL)THIO)PHENOXY)ACETAMIDE

Systematic Name

English

PEPA (DRUG)

Code

English

Code System Code Type Description

WIKIPEDIA

PEPA_(drug)