Vilastobart

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 11:47:26 GMT 2025` Edited by `admin` on `Wed Apr 02 11:47:26 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Type	COMPLETE
Record UNII	8FUE2D4G82
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Immunoglobulin G1 [241-aspartic acid,334-glutamic acid], anti-(human cytotoxic T-lymphocyte-associated protein 4) (human-Rattus norvegicus monoclonal XTX101 ?1-chain), disulfide with prodomain protein (synthetic masking moiety and protease-cleavable moie

Preferred Name

English

Vilastobart

Official Name

English

vilastobart [INN]

Common Name

English

XTX-101

Code

English

XTX101

Code

English

VILASTOBART [USAN]

Common Name

English

gamma1 heavy chain humanized (1-449) [VH (Homo sapiens IGHV1-69*08 (84.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT[8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, D12, L14, G1v7 CH2 D3, E117 (CH1 K120 (216) (120-217), hinge 1-

Common Name

English

CTLA4 (cytotoxic T-lymphocyte associated protein 4, CTLA-4, CD152)], humanized monoclonal antibody; gamma1 heavy chain humanized (1-449) [VH (Homo sapiens IGHV1-69*08 (84.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Hom

Systematic Name

English

Code System Code Type Description

NCI_THESAURUS

C203034