Vilastobart

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 18:37:20 GMT 2023` Edited by `admin` on `Sat Dec 16 18:37:20 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Type	COMPLETE
Record UNII	8FUE2D4G82
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Vilastobart

Official Name

English

immunoglobulin G1-fused prodomain kappa, anti-[Homo sapiens CTLA4 (cytotoxic T-lymphocyte associated protein 4, CTLA-4, CD152)], humanized monoclonal antibody

Common Name

English

vilastobart [INN]

Common Name

English

gamma1 heavy chain humanized (1-449) [VH (Homo sapiens IGHV1-69*08 (84.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT[8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, D12, L14, G1v7 CH2 D3, E117 (CH1 K120 (216) (120-217), hinge 1-

Common Name

English

Code System Code Type Description

CAS

2760549-50-4

Created by admin on Sat Dec 16 18:37:20 GMT 2023 , Edited by admin on Sat Dec 16 18:37:20 GMT 2023

PRIMARY

INN

12761

Created by admin on Sat Dec 16 18:37:20 GMT 2023 , Edited by admin on Sat Dec 16 18:37:20 GMT 2023

PRIMARY

FDA UNII

8FUE2D4G82

Created by admin on Sat Dec 16 18:37:20 GMT 2023 , Edited by admin on Sat Dec 16 18:37:20 GMT 2023

PRIMARY

From	To
4_161	4_221
4_51	4_115
4_2	4_10
3_161	3_221
3_51	3_115
3_2	3_10
2_369	2_427
2_263	2_323
2_222	4_241
2_146	2_202
2_22	2_96
1_369	1_427
1_263	1_323
1_231	2_231
1_228	2_228
1_222	3_241
1_146	1_202
1_22	1_96

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_299
N	2_299

Related Record Type Details


					8FUE2D4G82

Vilastobart

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL