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Details

Stereochemistry ACHIRAL
Molecular Formula C9H9Cl2NO2
Molecular Weight 234.079
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DILOXANIDE

SMILES

CN(C(=O)C(Cl)Cl)C1=CC=C(O)C=C1

InChI

InChIKey=GZZZSOOGQLOEOB-UHFFFAOYSA-N
InChI=1S/C9H9Cl2NO2/c1-12(9(14)8(10)11)6-2-4-7(13)5-3-6/h2-5,8,13H,1H3

HIDE SMILES / InChI

Molecular Formula C9H9Cl2NO2
Molecular Weight 234.079
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Diloxanide (used in the form of furoate) was developed for the treatment of intestinal amoebiasis. The effectiveness of the drug was proved in clinical trials, however, the mechanism of its action is unknown. The drug is not marketed in the United States, athough it is available in India.

Originator

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
DILOXANIDE FUROATE

PubMed

Sample Use Guides

In Vivo Use Guide
500mg 3 times daily for 5 days or 20mg/kg/daily divided into 3 daily doses for 10 days.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
89134SCM7M
Record Status Validated (UNII)
Record Version