ANIDOXIME

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H27N3O3
Molecular Weight	369.4574
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCN(CC)CCC(=NOC(=O)NC1=CC=C(OC)C=C1)C2=CC=CC=C2

InChI

InChIKey=XPHBRTNHVJSEQD-UHFFFAOYSA-N

InChI=1S/C21H27N3O3/c1-4-24(5-2)16-15-20(17-9-7-6-8-10-17)23-27-21(25)22-18-11-13-19(26-3)14-12-18/h6-14H,4-5,15-16H2,1-3H3,(H,22,25)

HIDE SMILES / InChI

Molecular Formula	C21H27N3O3
Molecular Weight	369.4574
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/334207

Anidoxime is unrelated to other analgesic agents in clinical use. It is the hydrochloride salt of 0-(4-methoxyphenyl-carboxyl)-3-diethylamino-propiophenone oxime, with an empirical formula C21H27N3O3 HCl. It was in clinical trial as an oral analgesic agent.

Approval Year

PubMed

Title	Date	PubMed
Anidoxime: a clinical trial of an oral analgesic agent.	1977 Mar	334207
Comparative analgesic, behavioral, and dependence properties of morphine and O-(4-methoxylphenylcarbamoyl)-3-diethylaminopropiophenone oxime hydrochloride.	1980 Feb	7188962

Patents

Sample Use Guides

In Vivo Use Guide

The new oral analgesic drug anidoxime was compared with dihydrocodeine. There were no side-effects, and no significant differences between the effects of dihydrocodeine 50 mg, anidoxime 75 mg or anidoxime 100 mg.

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:20:55 GMT 2023` Edited by `admin` on `Sat Dec 16 16:20:55 GMT 2023`
Record UNII	88ETS2Q7LZ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ANIDOXIME

Official Name

English

ANIDOXIME [USAN]

Common Name

English

anidoxime [INN]

Common Name

English

1-PROPANONE, 3-(DIETHYLAMINO)-1-PHENYL-, O-(((4-METHOXYPHENYL)AMINO)CARBONYL)OXIME

Common Name

English

3-(DIETHYLAMINO)PROPIOPHENONE O-((P-METHOXYPHENYL)CARBAMOYL)OXIME

Common Name

English

ANDIOXIME

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C241