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Details

Stereochemistry ACHIRAL
Molecular Formula C21H27N3O3.ClH
Molecular Weight 405.918
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of ANIDOXIME HYDROCHLORIDE

SMILES

Cl.CCN(CC)CCC(=NOC(=O)NC1=CC=C(OC)C=C1)C2=CC=CC=C2

InChI

InChIKey=BXYLCIMGDIDYPP-UHFFFAOYSA-N
InChI=1S/C21H27N3O3.ClH/c1-4-24(5-2)16-15-20(17-9-7-6-8-10-17)23-27-21(25)22-18-11-13-19(26-3)14-12-18;/h6-14H,4-5,15-16H2,1-3H3,(H,22,25);1H

HIDE SMILES / InChI
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C21H27N3O3
Molecular Weight 369.4574
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

Description

Anidoxime is unrelated to other analgesic agents in clinical use. It is the hydrochloride salt of 0-(4-methoxyphenyl-carboxyl)-3-diethylamino-propiophenone oxime, with an empirical formula C21H27N3O3 HCl. It was in clinical trial as an oral analgesic agent.

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
Anidoxime: a clinical trial of an oral analgesic agent.
1977 Mar
Comparative analgesic, behavioral, and dependence properties of morphine and O-(4-methoxylphenylcarbamoyl)-3-diethylaminopropiophenone oxime hydrochloride.
1980 Feb
Patents

Patents

EP2255184A2
2

Sample Use Guides

In Vivo Use Guide
The new oral analgesic drug anidoxime was compared with dihydrocodeine. There were no side-effects, and no significant differences between the effects of dihydrocodeine 50 mg, anidoxime 75 mg or anidoxime 100 mg.
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:48:57 GMT 2023
Edited
by admin
on Fri Dec 15 15:48:57 GMT 2023
Record UNII
70QM1XR26G
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ANIDOXIME HYDROCHLORIDE
Common Name English
1-PROPANONE, 3-(DIETHYLAMINO)-1-PHENYL-, O-(((4-METHOXYPHENYL)AMINO)CARBONYL)OXIME, MONOHYDROCHLORIDE
Systematic Name English
O-(4-METHOXYPHENYLCARBAMOYL)-3-DIETHYLAMINOPROPIOPHENONE OXIME HYDROCHLORIDE
Systematic Name English
Code System Code Type Description
CAS
31729-11-0
Created by admin on Fri Dec 15 15:48:57 GMT 2023 , Edited by admin on Fri Dec 15 15:48:57 GMT 2023
PRIMARY
FDA UNII
70QM1XR26G
Created by admin on Fri Dec 15 15:48:57 GMT 2023 , Edited by admin on Fri Dec 15 15:48:57 GMT 2023
PRIMARY
PUBCHEM
35883
Created by admin on Fri Dec 15 15:48:57 GMT 2023 , Edited by admin on Fri Dec 15 15:48:57 GMT 2023
PRIMARY
Related Record Type Details
Structure of ANIDOXIME
PARENT -> SALT/SOLVATE
NIH
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