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Details

Stereochemistry ACHIRAL
Molecular Formula C21H27N3O3.ClH
Molecular Weight 405.918
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of ANIDOXIME HYDROCHLORIDE

SMILES

Cl.CCN(CC)CCC(=NOC(=O)NC1=CC=C(OC)C=C1)C2=CC=CC=C2

InChI

InChIKey=BXYLCIMGDIDYPP-UHFFFAOYSA-N
InChI=1S/C21H27N3O3.ClH/c1-4-24(5-2)16-15-20(17-9-7-6-8-10-17)23-27-21(25)22-18-11-13-19(26-3)14-12-18;/h6-14H,4-5,15-16H2,1-3H3,(H,22,25);1H

HIDE SMILES / InChI
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C21H27N3O3
Molecular Weight 369.4574
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

Description

Anidoxime is unrelated to other analgesic agents in clinical use. It is the hydrochloride salt of 0-(4-methoxyphenyl-carboxyl)-3-diethylamino-propiophenone oxime, with an empirical formula C21H27N3O3 HCl. It was in clinical trial as an oral analgesic agent.

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
Comparative analgesic, behavioral, and dependence properties of morphine and O-(4-methoxylphenylcarbamoyl)-3-diethylaminopropiophenone oxime hydrochloride.
1980 Feb
Patents

Patents

EP2255184A2
2

Sample Use Guides

In Vivo Use Guide
The new oral analgesic drug anidoxime was compared with dihydrocodeine. There were no side-effects, and no significant differences between the effects of dihydrocodeine 50 mg, anidoxime 75 mg or anidoxime 100 mg.
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:48:57 GMT 2023
Edited
by admin
on Fri Dec 15 15:48:57 GMT 2023
Record UNII
70QM1XR26G
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ANIDOXIME HYDROCHLORIDE
Common Name English
1-PROPANONE, 3-(DIETHYLAMINO)-1-PHENYL-, O-(((4-METHOXYPHENYL)AMINO)CARBONYL)OXIME, MONOHYDROCHLORIDE
Systematic Name English
O-(4-METHOXYPHENYLCARBAMOYL)-3-DIETHYLAMINOPROPIOPHENONE OXIME HYDROCHLORIDE
Systematic Name English
Code System Code Type Description
CAS
31729-11-0
Created by admin on Fri Dec 15 15:48:57 GMT 2023 , Edited by admin on Fri Dec 15 15:48:57 GMT 2023
PRIMARY
FDA UNII
70QM1XR26G
Created by admin on Fri Dec 15 15:48:57 GMT 2023 , Edited by admin on Fri Dec 15 15:48:57 GMT 2023
PRIMARY
PUBCHEM
35883
Created by admin on Fri Dec 15 15:48:57 GMT 2023 , Edited by admin on Fri Dec 15 15:48:57 GMT 2023
PRIMARY
Related Record Type Details
Structure of ANIDOXIME
PARENT -> SALT/SOLVATE
NIH
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