DACEMAZINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H16N2OS
Molecular Weight	284.376
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN(C)CC(=O)N1C2=CC=CC=C2SC3=C1C=CC=C3

InChI

InChIKey=HKUCYAHWPVLPFN-UHFFFAOYSA-N

InChI=1S/C16H16N2OS/c1-17(2)11-16(19)18-12-7-3-5-9-14(12)20-15-10-6-4-8-13(15)18/h3-10H,11H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C16H16N2OS
Molecular Weight	284.376
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://actachemscand.org/pdf/acta_vol_05_p0102-0114.pdf | https://books.google.ru/books?id=0vXTBwAAQBAJ&pg=RA1-PA432&dq=Codopectyl

Dacemazine is a derivative of phenothiazine which acts as an antagonist of a histamine H1 receptor. The compound demonstrates local anesthetic activity and reduced the spasms produced by acetylcholine and histamine. In combination with di-tert-butylnaphthalenesulfonate, dacemazine was marketed under tradename Codopectyl as a spasmolytic and antitussive agent.

Approval Year

PubMed

Title	Date	PubMed
[Disturbing effect of N-dimethylamino acetylphenothiazide in layer chromatographic determination of pregnanediol isomers].	1972	5023028

Patents

Substance Class	Chemical Created by `admin` on `Wed Apr 02 07:07:46 GMT 2025` Edited by `admin` on `Wed Apr 02 07:07:46 GMT 2025`
Record UNII	88D34UY0QI
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

AHISTAN

Preferred Name

English

DACEMAZINE

Official Name

English

10-(N,N-DIMETHYLGLYCYL)PHENOTHIAZINE

Systematic Name

English

AHISTAN [MI]

Common Name

English

dacemazine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29578