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Details

Stereochemistry ACHIRAL
Molecular Formula C16H16N2OS.ClH
Molecular Weight 320.837
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DACEMAZINE HYDROCHLORIDE

SMILES

Cl.CN(C)CC(=O)N1C2=CC=CC=C2SC3=C1C=CC=C3

InChI

InChIKey=AZYRYQJAXSKKEK-UHFFFAOYSA-N
InChI=1S/C16H16N2OS.ClH/c1-17(2)11-16(19)18-12-7-3-5-9-14(12)20-15-10-6-4-8-13(15)18;/h3-10H,11H2,1-2H3;1H

HIDE SMILES / InChI

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C16H16N2OS
Molecular Weight 284.376
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Dacemazine is a derivative of phenothiazine which acts as an antagonist of a histamine H1 receptor. The compound demonstrates local anesthetic activity and reduced the spasms produced by acetylcholine and histamine. In combination with di-tert-butylnaphthalenesulfonate, dacemazine was marketed under tradename Codopectyl as a spasmolytic and antitussive agent.

Approval Year

PubMed

PubMed

TitleDatePubMed
[Disturbing effect of N-dimethylamino acetylphenothiazide in layer chromatographic determination of pregnanediol isomers].
1972
Patents
Substance Class Chemical
Created
by admin
on Sat Dec 16 11:24:26 GMT 2023
Edited
by admin
on Sat Dec 16 11:24:26 GMT 2023
Record UNII
DK78VKA001
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DACEMAZINE HYDROCHLORIDE
Common Name English
PHENOTHIAZINE, 10-(N,N-DIMETHYLGLYCYL)-, MONOHYDROCHLORIDE
Systematic Name English
10-(N,N-DIMETHYLGLYCYL)PHENOTHIAZINE HYDROCHLORIDE
Systematic Name English
AHISTAN HYDROCHLORIDE [MI]
Common Name English
ETHANONE, 2-(DIMETHYLAMINO)-1-(10H-PHENOTHIAZIN-10-YL)-, HYDROCHLORIDE (1:1)
Systematic Name English
AHISTAN HYDROCHLORIDE
MI  
Common Name English
Code System Code Type Description
FDA UNII
DK78VKA001
Created by admin on Sat Dec 16 11:24:26 GMT 2023 , Edited by admin on Sat Dec 16 11:24:26 GMT 2023
PRIMARY
CAS
25384-29-6
Created by admin on Sat Dec 16 11:24:26 GMT 2023 , Edited by admin on Sat Dec 16 11:24:26 GMT 2023
PRIMARY
MERCK INDEX
m546
Created by admin on Sat Dec 16 11:24:26 GMT 2023 , Edited by admin on Sat Dec 16 11:24:26 GMT 2023
PRIMARY Merck Index
PUBCHEM
90479044
Created by admin on Sat Dec 16 11:24:26 GMT 2023 , Edited by admin on Sat Dec 16 11:24:26 GMT 2023
PRIMARY
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ACTIVE MOIETY