ETYMEMAZINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Possibly Marketed Outside US

Details

Stereochemistry	RACEMIC
Molecular Formula	C20H26N2S
Molecular Weight	326.499
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ETYMEMAZINE

Structure Search

SMILES

CCC1=CC2=C(SC3=C(C=CC=C3)N2CC(C)CN(C)C)C=C1

InChI

InChIKey=USKHCLAXJXCWMO-UHFFFAOYSA-N

InChI=1S/C20H26N2S/c1-5-16-10-11-20-18(12-16)22(14-15(2)13-21(3)4)17-8-6-7-9-19(17)23-20/h6-12,15H,5,13-14H2,1-4H3

HIDE SMILES / InChI

Molecular Formula	C20H26N2S
Molecular Weight	326.499
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.drugs.com/international/etymemazine.html | https://www.drugfuture.com/chemdata/etymemazine.html | https://www.ncbi.nlm.nih.gov/pubmed/14493669 | https://www.ncbi.nlm.nih.gov/pubmed/14099369 | https://www.ncbi.nlm.nih.gov/pubmed/5668177

Etymemazine (RP-6484), a phenothiazine derivative, is a sedative and neuroleptic agent. It is a histamine H₁-receptor antagonist. It was used to treat dementia. It was also used in veterinary.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
[DEMENTIA PRAECOX. CURE BY RP-6484].	1963 Dec	14099369

Sample Use Guides

In Vivo Use Guide

Pigs: Ethyl isobutrazine (Etymemazine) and pethidine were each administered at a dose rate of 5 mg/kg

Route of Administration: Intramuscular

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:44:19 GMT 2023` Edited by `admin` on `Fri Dec 15 18:44:19 GMT 2023`
Record UNII	861J4K81C7
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ETYMEMAZINE

Official Name

English

ETHYLISOBUTRAZINE

Common Name

English

ETHOTRIMEPRAZINE

Common Name

English

etymemazine [INN]

Common Name

English

ETYMEMAZINE [MI]

Common Name

English

10-(3-(DIMETHYLAMINO)-2-METHYLPROPYL)-2-ETHYLPHENOTHIAZINE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29756

Created by admin on Fri Dec 15 18:44:19 GMT 2023 , Edited by admin on Fri Dec 15 18:44:19 GMT 2023

CFR

21 CFR 520.863

Created by admin on Fri Dec 15 18:44:19 GMT 2023 , Edited by admin on Fri Dec 15 18:44:19 GMT 2023

NCI_THESAURUS

C29578

Created by admin on Fri Dec 15 18:44:19 GMT 2023 , Edited by admin on Fri Dec 15 18:44:19 GMT 2023

CFR

21 CFR 522.863

Created by admin on Fri Dec 15 18:44:19 GMT 2023 , Edited by admin on Fri Dec 15 18:44:19 GMT 2023

Code System Code Type Description

FDA UNII

861J4K81C7

Created by admin on Fri Dec 15 18:44:19 GMT 2023 , Edited by admin on Fri Dec 15 18:44:19 GMT 2023

PRIMARY

DRUG CENTRAL

3742

Created by admin on Fri Dec 15 18:44:19 GMT 2023 , Edited by admin on Fri Dec 15 18:44:19 GMT 2023

PRIMARY

SMS_ID

100000082117

Created by admin on Fri Dec 15 18:44:19 GMT 2023 , Edited by admin on Fri Dec 15 18:44:19 GMT 2023

PRIMARY

EVMPD

SUB07349MIG

Created by admin on Fri Dec 15 18:44:19 GMT 2023 , Edited by admin on Fri Dec 15 18:44:19 GMT 2023

PRIMARY

INN

1391

Created by admin on Fri Dec 15 18:44:19 GMT 2023 , Edited by admin on Fri Dec 15 18:44:19 GMT 2023

PRIMARY

CAS

523-54-6

Created by admin on Fri Dec 15 18:44:19 GMT 2023 , Edited by admin on Fri Dec 15 18:44:19 GMT 2023

PRIMARY

ChEMBL

CHEMBL2008544

Created by admin on Fri Dec 15 18:44:19 GMT 2023 , Edited by admin on Fri Dec 15 18:44:19 GMT 2023

PRIMARY

DRUG BANK

DB11517

Created by admin on Fri Dec 15 18:44:19 GMT 2023 , Edited by admin on Fri Dec 15 18:44:19 GMT 2023

PRIMARY

PUBCHEM

71823

Created by admin on Fri Dec 15 18:44:19 GMT 2023 , Edited by admin on Fri Dec 15 18:44:19 GMT 2023

PRIMARY

NCI_THESAURUS

C73062

Created by admin on Fri Dec 15 18:44:19 GMT 2023 , Edited by admin on Fri Dec 15 18:44:19 GMT 2023

PRIMARY

EPA CompTox

DTXSID0046935

Created by admin on Fri Dec 15 18:44:19 GMT 2023 , Edited by admin on Fri Dec 15 18:44:19 GMT 2023

PRIMARY

MERCK INDEX

m728

Created by admin on Fri Dec 15 18:44:19 GMT 2023 , Edited by admin on Fri Dec 15 18:44:19 GMT 2023

PRIMARY

Merck Index

WIKIPEDIA

ETYMEMAZINE

Created by admin on Fri Dec 15 18:44:19 GMT 2023 , Edited by admin on Fri Dec 15 18:44:19 GMT 2023

PRIMARY

Related Record Type Details


					69826NE6QS

EVANDAMINE, (R)-

ENANTIOMER -> RACEMATE


					A7002E7T2Z

ETYMEMAZINE HYDROCHLORIDE

SALT/SOLVATE -> PARENT


					Z141N352WY

ETYMEMAZINE, (S)-

ENANTIOMER -> RACEMATE

Related Record Type Details


					861J4K81C7

ACTIVE MOIETY