ETYMEMAZINE HYDROCHLORIDE

Possibly Marketed Outside US

Details

Stereochemistry	RACEMIC
Molecular Formula	C20H26N2S.ClH
Molecular Weight	362.96
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CCC1=CC2=C(SC3=C(C=CC=C3)N2CC(C)CN(C)C)C=C1

InChI

InChIKey=ZVSKDFRXWJPINY-UHFFFAOYSA-N

InChI=1S/C20H26N2S.ClH/c1-5-16-10-11-20-18(12-16)22(14-15(2)13-21(3)4)17-8-6-7-9-19(17)23-20;/h6-12,15H,5,13-14H2,1-4H3;1H

HIDE SMILES / InChI

Molecular Formula	C20H26N2S
Molecular Weight	326.499
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.drugs.com/international/etymemazine.html | https://www.drugfuture.com/chemdata/etymemazine.html | https://www.ncbi.nlm.nih.gov/pubmed/14493669 | https://www.ncbi.nlm.nih.gov/pubmed/14099369 | https://www.ncbi.nlm.nih.gov/pubmed/5668177

Etymemazine (RP-6484), a phenothiazine derivative, is a sedative and neuroleptic agent. It is a histamine H₁-receptor antagonist. It was used to treat dementia. It was also used in veterinary.

Originator

Approval Year

PubMed

Title	Date	PubMed
[Clinical study of a new phenothiazine derivative, RP-6484].	1960 Jun 11	14436567
[On the clinical use in neuropsychiatry of 3-ethyl-10-(2-methyl-3-dimethylaminopropyl)-phenothiazine HCl (RP-6484), new phenothiazine neuroleptic].	1962 Jun 2	14493669
[DEMENTIA PRAECOX. CURE BY RP-6484].	1963 Dec	14099369

Sample Use Guides

In Vivo Use Guide

Pigs: Ethyl isobutrazine (Etymemazine) and pethidine were each administered at a dose rate of 5 mg/kg

Route of Administration: Intramuscular

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:06:47 GMT 2023` Edited by `admin` on `Fri Dec 15 16:06:47 GMT 2023`
Record UNII	A7002E7T2Z
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ETYMEMAZINE HYDROCHLORIDE

Common Name

English

10-(3-(DIMETHYLAMINO)-2-METHYLPROPYL)-2-ETHYLPHENOTHIAZINE HYDROCHLORIDE

Systematic Name

English

ETHYLISOBUTRAZINE HYDROCHLORIDE

Common Name

English

PHENOTHIAZINE, 10-(3-(DIMETHYLAMINO)-2-METHYLPROPYL)-2-ETHYL-, MONOHYDROCHLORIDE

Common Name

English

(±)-ETYMEMAZINE HYDROCHLORIDE

Common Name

English

NSC-169471

Code

English

ETYMEMAZINE HCL

Common Name

English

RP 6484

Code

English

ETYMEMAZINE HYDROCHLORIDE, (±)-

Common Name

English

ETHYMEMAZINE MONOHYDROCHLORIDE

Common Name

English

RP-6484

Code

English

10H-PHENOTHIAZINE-10-PROPANAMINE, 2-ETHYL-N,N,.BETA.-TRIMETHYL-,HYDROCHLORIDE (1:1)

Common Name

English

ETYMEMAZINE HYDROCHLORIDE [GREEN BOOK]

Common Name

English

SERGETYL

Brand Name

English

NUITAL

Brand Name

English

ETYMEMAZINE HYDROCHLORIDE [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29578