Details
Stereochemistry | ACHIRAL |
Molecular Formula | C22H18I6N2O9 |
Molecular Weight | 1215.8131 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)C1=C(I)C=C(I)C(NC(=O)COCCOCCOCC(=O)NC2=C(I)C=C(I)C(C(O)=O)=C2I)=C1I
InChI
InChIKey=JXMIBUGMYLQZGO-UHFFFAOYSA-N
InChI=1S/C22H18I6N2O9/c23-9-5-11(25)19(17(27)15(9)21(33)34)29-13(31)7-38-3-1-37-2-4-39-8-14(32)30-20-12(26)6-10(24)16(18(20)28)22(35)36/h5-6H,1-4,7-8H2,(H,29,31)(H,30,32)(H,33,34)(H,35,36)
Molecular Formula | C22H18I6N2O9 |
Molecular Weight | 1215.8131 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Iotroxic acid (INN), also known as meglumine iotroxate (BAN) (Biliscopin) for infusion is indicated for radiological examination of the hepatic and biliary ducts and gallbladder when examination by oral technique is unsuccessful or inappropriate. Following intravenous administration Biliscopin is rapidly excreted, mainly by the liver into the bile. Visualisation of the hepatic and common bile ducts and the gallbladder can, therefore, be achieved. Visualisation of the biliary ducts is usually possible 30-60 minutes after completion of administration. In vitro meglumine iotroxate binds to plasma proteins to the extent of 60-90% depending on concentration. In animals it crosses the placental barrier. This agent is the single intravenous cholangiographic agent, which is currently available in Australia.
Approval Year
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:37:16 GMT 2023
by
admin
on
Fri Dec 15 16:37:16 GMT 2023
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Record UNII |
84C5PTP9X6
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Record Status |
Validated (UNII)
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Record Version |
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Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C28500
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admin on Fri Dec 15 16:37:16 GMT 2023 , Edited by admin on Fri Dec 15 16:37:16 GMT 2023
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WHO-VATC |
QV08AC02
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admin on Fri Dec 15 16:37:16 GMT 2023 , Edited by admin on Fri Dec 15 16:37:16 GMT 2023
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WHO-ATC |
V08AC02
Created by
admin on Fri Dec 15 16:37:16 GMT 2023 , Edited by admin on Fri Dec 15 16:37:16 GMT 2023
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Code System | Code | Type | Description | ||
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Iotroxic acid
Created by
admin on Fri Dec 15 16:37:16 GMT 2023 , Edited by admin on Fri Dec 15 16:37:16 GMT 2023
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CHEMBL1651905
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3740
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100000083115
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84C5PTP9X6
Created by
admin on Fri Dec 15 16:37:16 GMT 2023 , Edited by admin on Fri Dec 15 16:37:16 GMT 2023
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3652
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SUB08261MIG
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51022-74-3
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DB08945
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C72080
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3991
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DTXSID3048782
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IOTROXIC ACID
Created by
admin on Fri Dec 15 16:37:16 GMT 2023 , Edited by admin on Fri Dec 15 16:37:16 GMT 2023
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PRIMARY | Description: An almost white powder. Solubility: Practically insoluble in water, benzene R, and ether R; freely soluble in methanol R and dimethylformamide R; dissolves in solutions of alkali hydroxides. Category: Used in the preparation of meglumine iotroxate as a radiocontrast medium. Storage: Iotroxic acid should be kept in a well-closed container, protected from light. Requirements: Iotroxic acid contains not less than 98.0% and not more than the equivalent of 102.0% of C22H18I6N2O9, calculated with reference to the anhydrous substance. | ||
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256-917-3
Created by
admin on Fri Dec 15 16:37:16 GMT 2023 , Edited by admin on Fri Dec 15 16:37:16 GMT 2023
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PRIMARY |
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SALT/SOLVATE -> PARENT |
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ACTIVE MOIETY |