Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C22H18I6N2O9.C7H17NO5 |
Molecular Weight | 1411.0267 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 4 / 4 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC(=O)C1=C(I)C=C(I)C(NC(=O)COCCOCCOCC(=O)NC2=C(I)C(C(O)=O)=C(I)C=C2I)=C1I
InChI
InChIKey=WLQIGBUDSUVJCO-WZTVWXICSA-N
InChI=1S/C22H18I6N2O9.C7H17NO5/c23-9-5-11(25)19(17(27)15(9)21(33)34)29-13(31)7-38-3-1-37-2-4-39-8-14(32)30-20-12(26)6-10(24)16(18(20)28)22(35)36;1-8-2-4(10)6(12)7(13)5(11)3-9/h5-6H,1-4,7-8H2,(H,29,31)(H,30,32)(H,33,34)(H,35,36);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1
Molecular Formula | C22H18I6N2O9 |
Molecular Weight | 1215.8131 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Molecular Formula | C7H17NO5 |
Molecular Weight | 195.2136 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 4 / 4 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Iotroxic acid (INN), also known as meglumine iotroxate (BAN) (Biliscopin) for infusion is indicated for radiological examination of the hepatic and biliary ducts and gallbladder when examination by oral technique is unsuccessful or inappropriate. Following intravenous administration Biliscopin is rapidly excreted, mainly by the liver into the bile. Visualisation of the hepatic and common bile ducts and the gallbladder can, therefore, be achieved. Visualisation of the biliary ducts is usually possible 30-60 minutes after completion of administration. In vitro meglumine iotroxate binds to plasma proteins to the extent of 60-90% depending on concentration. In animals it crosses the placental barrier. This agent is the single intravenous cholangiographic agent, which is currently available in Australia.
Approval Year
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 18:05:35 GMT 2023
by
admin
on
Fri Dec 15 18:05:35 GMT 2023
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Record UNII |
389136RRO0
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Record Status |
Validated (UNII)
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Record Version |
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-
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CHEMBL2110616
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C012386
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DBSALT002658
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68890-05-1
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119297
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389136RRO0
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SUB02755MIG
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52527
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admin on Fri Dec 15 18:05:35 GMT 2023 , Edited by admin on Fri Dec 15 18:05:35 GMT 2023
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DTXSID80218969
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admin on Fri Dec 15 18:05:35 GMT 2023 , Edited by admin on Fri Dec 15 18:05:35 GMT 2023
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100000092771
Created by
admin on Fri Dec 15 18:05:35 GMT 2023 , Edited by admin on Fri Dec 15 18:05:35 GMT 2023
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Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE | |||
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PARENT -> SALT/SOLVATE |